Star of Extinction

Destroy target land. Star of Extinction deals 20 damage to each creature and each planeswalker.

Time Wipe

Return a creature you control to its owner's hand, then destroy all creatures.

Despark

Exile target permanent with mana value 4 or greater.

Imprisoned in the Moon

Enchant creature, land, or planeswalker
Enchanted permanent is a colorless land with "{T}: Add {C}" and loses all other card types and abilities.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Fell

Olórin's Searing Light

Each opponent exiles a creature with the greatest power among creatures that player controls.
Spell mastery — If there are two or more instant and/or sorcery cards in your graveyard, Olórin's Searing Light deals damage to each opponent equal to the power of the creature they exiled.

Infernal Grasp

Destroy target creature. You lose 2 life.

Ruinous Ultimatum

Destroy all nonland permanents your opponents control.

Reality Shift

Exile target creature. Its controller manifests the top card of their library. (That player puts the top card of their library onto the battlefield face down as a 2/2 creature. If it's a creature card, it can be turned face up any time for its mana cost.)

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Organic Extinction

Improvise (Your artifacts can help cast this spell. Each artifact you tap after you're done activating mana abilities pays for {1}.)
Destroy all nonartifact creatures.

Lignify

Enchant creature
Enchanted creature is a Treefolk with base power and toughness 0/4 and loses all abilities.

Generous Gift

Destroy target permanent. Its controller creates a 3/3 green Elephant creature token.

Cyber Conversion

Turn target creature face down. It's a 2/2 Cyberman artifact creature.

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Delete

Delete deals X damage to each nonartifact creature and each player.

Darksteel Mutation

Enchant creature
Enchanted creature is an Insect artifact creature with base power and toughness 0/1 and has indestructible, and it loses all other abilities, card types, and creature types.

Slash the Ranks

Destroy all creatures and planeswalkers except for commanders.

Tragic Slip

Target creature gets -1/-1 until end of turn.
Morbid — That creature gets -13/-13 until end of turn instead if a creature died this turn.

Fateful Absence

Destroy target creature or planeswalker. Its controller investigates. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")

Deathsprout

Destroy target creature. Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Ezuri's Predation

For each creature your opponents control, create a 4/4 green Phyrexian Beast creature token. Each of those tokens fights a different one of those creatures.

Mizzium Mortars

Mizzium Mortars deals 4 damage to target creature you don't control.
Overload {3}{R}{R}{R} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Eaten by Piranhas

Flash (You may cast this spell any time you could cast an instant.)
Enchant creature
Enchanted creature loses all abilities and is a black Skeleton creature with base power and toughness 1/1. (It loses all other colors, card types, and creature types.)

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Putrefy

Destroy target artifact or creature. It can't be regenerated.

Stroke of Midnight

Destroy target nonland permanent. Its controller creates a 1/1 white Human creature token.

Beast Within

Destroy target permanent. Its controller creates a 3/3 green Beast creature token.

Vindicate

Astarion's Thirst

Exile target creature. Put X +1/+1 counters on a commander creature you control, where X is the power of the creature exiled this way.

Peer Pressure

Choose a creature type. If you control more creatures of that type than each other player, you gain control of all creatures of that type. (This effect lasts indefinitely.)

Damning Verdict

Destroy all creatures with no counters on them.

Murder

Supreme Verdict

This spell can't be countered.
Destroy all creatures.

Urza's Ruinous Blast

(You may cast a legendary sorcery only if you control a legendary creature or planeswalker.)
Exile all nonland permanents that aren't legendary.

Go for the Throat

Mortify

Mortality Spear

This spell costs {2} less to cast if you gained life this turn.
Destroy target nonland permanent.

Delayed Blast Fireball

Delayed Blast Fireball deals 2 damage to each opponent and each creature they control. If this spell was cast from exile, it deals 5 damage to each opponent and each creature they control instead.
Foretell {4}{R}{R} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Baleful Mastery

You may pay {1}{B} rather than pay this spell's mana cost.
If the {1}{B} cost was paid, an opponent draws a card.
Exile target creature or planeswalker.

Oubliette

When Oubliette enters, target creature phases out until Oubliette leaves the battlefield. Tap that creature as it phases in this way. (Auras and Equipment phase out with it. While permanents are phased out, they're treated as though they don't exist.)

Sunblast Angel

Flying
When Sunblast Angel enters, destroy all tapped creatures.

Kenrith's Transformation

Enchant creature
When Kenrith's Transformation enters, draw a card.
Enchanted creature loses all abilities and is a green Elk creature with base power and toughness 3/3. (It loses all other card types and creature types.)

Maelstrom Pulse

Destroy target nonland permanent and all other permanents with the same name as that permanent.

Defile

Target creature gets -1/-1 until end of turn for each Swamp you control.

Grasp of Fate

When Grasp of Fate enters, for each opponent, exile up to one target nonland permanent that player controls until Grasp of Fate leaves the battlefield. (Those permanents return under their owners' control.)

Chandra's Ignition

Target creature you control deals damage equal to its power to each other creature and each opponent.

Curse of the Swine

Exile X target creatures. For each creature exiled this way, its controller creates a 2/2 green Boar creature token.

Council's Judgment

Will of the council — Starting with you, each player votes for a nonland permanent you don't control. Exile each permanent with the most votes or tied for most votes.

Bitter Triumph

As an additional cost to cast this spell, discard a card or pay 3 life.
Destroy target creature or planeswalker.

Wild Magic Surge

Destroy target permanent an opponent controls. Its controller reveals cards from the top of their library until they reveal a permanent card that shares a card type with that permanent. They put that card onto the battlefield and the rest on the bottom of their library in a random order.

Detention Sphere

When Detention Sphere enters, you may exile target nonland permanent not named Detention Sphere and all other permanents with the same name as that permanent.
When Detention Sphere leaves the battlefield, return the exiled cards to the battlefield under their owner's control.

Price of Fame

This spell costs {2} less to cast if it targets a legendary creature.
Destroy target creature.
Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Get Lost

Destroy target creature, enchantment, or planeswalker. Its controller creates two Map tokens. (They're artifacts with "{1}, {T}, Sacrifice this artifact: Target creature you control explores. Activate only as a sorcery.")

Echoing Truth

Return target nonland permanent and all other permanents with the same name as that permanent to their owners' hands.

Rapid Hybridization

Destroy target creature. It can't be regenerated. That creature's controller creates a 3/3 green Frog Lizard creature token.

Song of the Dryads

Enchant permanent
Enchanted permanent is a colorless Forest land.

Winds of Rath

Destroy all creatures that aren't enchanted. They can't be regenerated.

Hour of Reckoning

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Destroy all nontoken creatures.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Crux of Fate

Choose one —
• Destroy all Dragon creatures.
• Destroy all non-Dragon creatures.

Chain Reaction

Chain Reaction deals X damage to each creature, where X is the number of creatures on the battlefield.

Crippling Fear

Choose a creature type. Creatures that aren't of the chosen type get -3/-3 until end of turn.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.