Terminate

Destroy target creature. It can't be regenerated.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Kaervek the Merciless

Whenever an opponent casts a spell, Kaervek deals damage equal to that spell's mana value to any target.

Vandalblast

Destroy target artifact you don't control.
Overload {4}{R} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Angrath, the Flame-Chained

+1: Each opponent discards a card and loses 2 life.
−3: Gain control of target creature until end of turn. Untap it. It gains haste until end of turn. Sacrifice it at the beginning of the next end step if it has mana value 3 or less.
−8: Each opponent loses life equal to the number of cards in their graveyard.

Dreadbore

Theater of Horrors

At the beginning of your upkeep, exile the top card of your library.
During your turn, if an opponent lost life this turn, you may play lands and cast spells from among cards exiled with this enchantment.
{3}{R}: This enchantment deals 1 damage to target opponent or planeswalker.

Rakdos Signet

Unlicensed Disintegration

Destroy target creature. If you control an artifact, Unlicensed Disintegration deals 3 damage to that creature's controller.

Vial Smasher the Fierce

Whenever you cast your first spell each turn, choose an opponent at random. Vial Smasher deals damage equal to that spell's mana value to that player or a planeswalker that player controls.
Partner (You can have two commanders if both have partner.)

Talisman of Indulgence

{T}: Add {C}.
{T}: Add {B} or {R}. This artifact deals 1 damage to you.

Tymaret, the Murder King

{1}{R}, Sacrifice another creature: Tymaret deals 2 damage to target player or planeswalker.
{1}{B}, Sacrifice a creature: Return this card from your graveyard to your hand.

Xantcha, Sleeper Agent

Xantcha enters under the control of an opponent of your choice.
Xantcha attacks each combat if able and can't attack its owner or planeswalkers its owner controls.
{3}: Xantcha's controller loses 2 life and you draw a card. Any player may activate this ability.

Olivia Voldaren

Flying
{1}{R}: Olivia Voldaren deals 1 damage to another target creature. That creature becomes a Vampire in addition to its other types. Put a +1/+1 counter on Olivia Voldaren.
{3}{B}{B}: Gain control of target Vampire for as long as you control Olivia Voldaren.

Lyzolda, the Blood Witch

{2}, Sacrifice a creature: Lyzolda deals 2 damage to any target if the sacrificed creature was red. Draw a card if the sacrificed creature was black.

Rakdos, Lord of Riots

You can't cast Rakdos unless an opponent lost life this turn.
Flying, trample
Creature spells you cast cost {1} less to cast for each 1 life your opponents have lost this turn.

The Scorpion God

Whenever a creature with a -1/-1 counter on it dies, draw a card.
{1}{B}{R}: Put a -1/-1 counter on another target creature.
When The Scorpion God dies, return it to its owner's hand at the beginning of the next end step.

Palace Siege

As this enchantment enters, choose Khans or Dragons.
• Khans — At the beginning of your upkeep, return target creature card from your graveyard to your hand.
• Dragons — At the beginning of your upkeep, each opponent loses 2 life and you gain 2 life.

Judith, the Scourge Diva

Other creatures you control get +1/+0.
Whenever a nontoken creature you control dies, Judith deals 1 damage to any target.

Havoc Festival

Players can't gain life.
At the beginning of each player's upkeep, that player loses half their life, rounded up.

Mogis, God of Slaughter

Indestructible
As long as your devotion to black and red is less than seven, Mogis isn't a creature.
At the beginning of each opponent's upkeep, Mogis deals 2 damage to that player unless they sacrifice a creature of their choice.