Niv-Mizzet, Guildpact

Flying, hexproof from multicolored
Whenever Niv-Mizzet, Guildpact deals combat damage to a player, it deals X damage to any target, target player draws X cards, and you gain X life, where X is the number of different color pairs among permanents you control that are exactly two colors.

Inga and Esika

Creatures you control have vigilance and "{T}: Add one mana of any color. Spend this mana only to cast a creature spell."
Whenever you cast a creature spell, if three or more mana from creatures was spent to cast it, draw a card.

Ephara, Ever-Sheltering

Ephara, Ever-Sheltering has lifelink and indestructible as long as you control at least three other enchantments.
Whenever another enchantment you control enters, draw a card.

Invasion of Theros

(As a Siege enters, choose an opponent to protect it. You and others can attack it. When it's defeated, exile it, then cast it transformed.)
When Invasion of Theros enters, search your library for an Aura, God, or Demigod card, reveal it, put it into your hand, then shuffle.

Invasion of Theros // Ephara, Ever-Sheltering

Iroas, God of Victory

Indestructible
As long as your devotion to red and white is less than seven, Iroas isn't a creature.
Creatures you control have menace.
Prevent all damage that would be dealt to attacking creatures you control.

Sol Ring

Tyrite Sanctum

{T}: Add {C}.
{2}, {T}: Target legendary creature becomes a God in addition to its other types. Put a +1/+1 counter on it.
{4}, {T}, Sacrifice Tyrite Sanctum: Put an indestructible counter on target God.

Karametra, God of Harvests

Indestructible
As long as your devotion to green and white is less than seven, Karametra isn't a creature.
Whenever you cast a creature spell, you may search your library for a Forest or Plains card, put it onto the battlefield tapped, then shuffle.

Soulherder

Whenever a creature is exiled from the battlefield, put a +1/+1 counter on Soulherder.
At the beginning of your end step, you may exile another target creature you control, then return that card to the battlefield under its owner's control.

Time Wipe

Return a creature you control to its owner's hand, then destroy all creatures.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Sythis, Harvest's Hand

Whenever you cast an enchantment spell, you gain 1 life and draw a card.

Kruphix, God of Horizons

Indestructible
As long as your devotion to green and blue is less than seven, Kruphix isn't a creature.
You have no maximum hand size.
If you would lose unspent mana, that mana becomes colorless instead.

Child of Alara

Trample
When Child of Alara dies, destroy all nonland permanents. They can't be regenerated.

Keranos, God of Storms

Indestructible
As long as your devotion to blue and red is less than seven, Keranos isn't a creature.
Reveal the first card you draw on each of your turns. Whenever you reveal a land card this way, draw a card. Whenever you reveal a nonland card this way, Keranos deals 3 damage to any target.

Klothys, God of Destiny

Indestructible
As long as your devotion to red and green is less than seven, Klothys isn't a creature.
At the beginning of your first main phase, exile target card from a graveyard. If it was a land card, add {R} or {G}. Otherwise, you gain 2 life and Klothys deals 2 damage to each opponent.

Birds of Paradise

Growth Spiral

Draw a card. You may put a land card from your hand onto the battlefield.

Supreme Verdict

This spell can't be countered.
Destroy all creatures.

Wrath of God

Destroy all creatures. They can't be regenerated.

Xenagos, God of Revels

Indestructible
As long as your devotion to red and green is less than seven, Xenagos isn't a creature.
At the beginning of combat on your turn, another target creature you control gains haste and gets +X/+X until end of turn, where X is that creature's power.

The World Tree

The World Tree enters tapped.
{T}: Add {G}.
As long as you control six or more lands, lands you control have "{T}: Add one mana of any color."
{W}{W}{U}{U}{B}{B}{R}{R}{G}{G}, {T}, Sacrifice The World Tree: Search your library for any number of God cards, put them onto the battlefield, then shuffle.

Djeru and Hazoret

As long as you have one or fewer cards in hand, Djeru and Hazoret has vigilance and haste.
Whenever Djeru and Hazoret attacks, look at the top six cards of your library. You may exile a legendary creature card from among them. Put the rest on the bottom of your library in a random order. Until end of turn, you may cast the exiled card without paying its mana cost.

Azorius Charm

Choose one —
• Creatures you control gain lifelink until end of turn.
• Draw a card.
• Put target attacking or blocking creature on top of its owner's library.

The Apprentice's Folly

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I, II — Choose target nontoken creature you control that doesn't have the same name as a token you control. Create a token that's a copy of it, except it isn't legendary, is a Reflection in addition to its other types, and has haste.
III — Sacrifice all Reflections you control.

Golgari Charm

Choose one —
• All creatures get -1/-1 until end of turn.
• Destroy target enchantment.
• Regenerate each creature you control.

Uro, Titan of Nature's Wrath

When Uro enters, sacrifice it unless it escaped.
Whenever Uro enters or attacks, you gain 3 life and draw a card, then you may put a land card from your hand onto the battlefield.
Escape—{G}{G}{U}{U}, Exile five other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Dovin's Veto

This spell can't be countered.
Counter target noncreature spell.

Relic of Legends

{T}: Add one mana of any color.
Tap an untapped legendary creature you control: Add one mana of any color.

Faeburrow Elder

Vigilance
Faeburrow Elder gets +1/+1 for each color among permanents you control.
{T}: For each color among permanents you control, add one mana of that color.

Guildpact Paragon

Whenever you cast a spell that's exactly two colors, look at the top six cards of your library. You may reveal a card that's exactly two colors from among them and put it into your hand. Put the rest on the bottom of your library in a random order.

Invasion of Ravnica

(As a Siege enters, choose an opponent to protect it. You and others can attack it. When it's defeated, exile it, then cast it transformed.)
When Invasion of Ravnica enters, exile target nonland permanent an opponent controls that isn't exactly two colors.

Invasion of Ravnica // Guildpact Paragon

Command Tower

Niv-Mizzet Reborn

Flying
When Niv-Mizzet Reborn enters, reveal the top ten cards of your library. For each color pair, choose a card that's exactly those colors from among them. Put the chosen cards into your hand and the rest on the bottom of your library in a random order.

Mogis, God of Slaughter

Indestructible
As long as your devotion to black and red is less than seven, Mogis isn't a creature.
At the beginning of each opponent's upkeep, Mogis deals 2 damage to that player unless they sacrifice a creature of their choice.

Enchantress's Presence

Whenever you cast an enchantment spell, draw a card.

Herald of the Pantheon

Enchantment spells you cast cost {1} less to cast.
Whenever you cast an enchantment spell, you gain 1 life.

Athreos, Shroud-Veiled

Indestructible
As long as your devotion to white and black is less than seven, Athreos isn't a creature.
At the beginning of your end step, put a coin counter on another target creature.
Whenever a creature with a coin counter on it dies or is put into exile, return that card to the battlefield under your control.

Altar of the Pantheon

Your devotion to each color and each combination of colors is increased by one.
{T}: Add one mana of any color. If you control a God, a Demigod, or a legendary enchantment, you gain 1 life.

Ephara, God of the Polis

Indestructible
As long as your devotion to white and blue is less than seven, Ephara isn't a creature.
At the beginning of each upkeep, if you had another creature enter the battlefield under your control last turn, draw a card.

Tome of the Guildpact

Whenever you cast a multicolored spell, draw a card.
{T}: Add one mana of any color.