Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Agent of the Iron Throne

Commander creatures you own have "Whenever an artifact or creature you control is put into a graveyard from the battlefield, each opponent loses 1 life."

Mage Hunter

Whenever an opponent casts or copies an instant or sorcery spell, they lose 1 life.

Spitfire Lagac

Landfall — Whenever a land you control enters, this creature deals 1 damage to each opponent.

Sphere of Purity

If an artifact would deal damage to you, prevent 1 of that damage.

Ill-Gotten Inheritance

At the beginning of your upkeep, Ill-Gotten Inheritance deals 1 damage to each opponent and you gain 1 life.
{5}{B}, Sacrifice Ill-Gotten Inheritance: It deals 4 damage to target opponent and you gain 4 life.

Consuming Sepulcher

At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Tithing Blade

When Tithing Blade enters, each opponent sacrifices a creature of their choice.
Craft with creature {4}{B} ({4}{B}, Exile this artifact, Exile a creature you control or a creature card from your graveyard: Return this card transformed under its owner's control. Craft only as a sorcery.)

Tithing Blade // Consuming Sepulcher

Ghyrson Starn, Kelermorph

Ward {2} (Whenever this creature becomes the target of a spell or ability an opponent controls, counter it unless that player pays {2}.)
Three Autostubs — Whenever another source you control deals exactly 1 damage to a permanent or player, Ghyrson Starn, Kelermorph deals 2 damage to that permanent or player.

Plague Spitter

At the beginning of your upkeep, Plague Spitter deals 1 damage to each creature and each player.
When Plague Spitter dies, it deals 1 damage to each creature and each player.

Scholar of Athreos

{2}{B}: Each opponent loses 1 life. You gain life equal to the life lost this way.

Steam Clean

Return target nonland permanent to its owner's hand. (Then exile this card. You may cast the creature later from exile.)

Scalding Viper

Whenever an opponent casts a spell with mana value 3 or less, Scalding Viper deals 1 damage to that player.

Scalding Viper // Steam Clean

Royal Decree

Cumulative upkeep {W} (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
Whenever a Swamp, Mountain, black permanent, or red permanent becomes tapped, Royal Decree deals 1 damage to that permanent's controller.

God-Pharaoh's Statue

Spells your opponents cast cost {2} more to cast.
At the beginning of your end step, each opponent loses 1 life.

Faerie Tauntings

Whenever you cast a spell during an opponent's turn, you may have each opponent lose 1 life.

Spiteful Visions

At the beginning of each player's draw step, that player draws an additional card.
Whenever a player draws a card, Spiteful Visions deals 1 damage to that player.

Pyrohemia

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pyrohemia.
{R}: Pyrohemia deals 1 damage to each creature and each player.

Sardian Avenger

First strike, trample
Whenever Sardian Avenger attacks, it gets +X/+0 until end of turn, where X is the number of artifacts your opponents control.
Whenever an artifact an opponent controls is put into a graveyard from the battlefield, Sardian Avenger deals 1 damage to that player.

Squallmonger

{2}: Squallmonger deals 1 damage to each creature with flying and each player. Any player may activate this ability.

Razortip Whip

{1}, {T}: Razortip Whip deals 1 damage to target opponent or planeswalker.

Oloro, Ageless Ascetic

At the beginning of your upkeep, you gain 2 life.
Whenever you gain life, you may pay {1}. If you do, draw a card and each opponent loses 1 life.
At the beginning of your upkeep, if Oloro, Ageless Ascetic is in the command zone, you gain 2 life.

Battle Strain

Whenever a creature blocks, Battle Strain deals 1 damage to that creature's controller.

Soul Bleed

Enchant creature
At the beginning of the upkeep of enchanted creature's controller, that player loses 1 life.

Spawn of Mayhem

Spectacle {1}{B}{B} (You may cast this spell for its spectacle cost rather than its mana cost if an opponent lost life this turn.)
Flying, trample
At the beginning of your upkeep, Spawn of Mayhem deals 1 damage to each player. Then if you have 10 or less life, put a +1/+1 counter on Spawn of Mayhem.

Scald

Whenever a player taps an Island for mana, Scald deals 1 damage to that player.

Blood Tyrant

Flying, trample
At the beginning of your upkeep, each player loses 1 life. Put a +1/+1 counter on Blood Tyrant for each 1 life lost this way.
Whenever a player loses the game, put five +1/+1 counters on Blood Tyrant.

Nightshade Harvester

Whenever a land an opponent controls enters, that player loses 1 life. Put a +1/+1 counter on Nightshade Harvester.

Dreadhound

When Dreadhound enters, mill three cards. (Put the top three cards of your library into your graveyard.)
Whenever a creature dies or a creature card is put into a graveyard from a library, each opponent loses 1 life.

Barbed Wire

At the beginning of each player's upkeep, Barbed Wire deals 1 damage to that player.
{2}: Prevent the next 1 damage that would be dealt by Barbed Wire this turn.

Davros, Dalek Creator

Menace
At the beginning of your end step, create a 3/3 black Dalek artifact creature token with menace if an opponent lost 3 or more life this turn. Then each opponent who lost 3 or more life this turn faces a villainous choice — You draw a card, or that player discards a card.

Gonti's Machinations

Whenever you lose life for the first time each turn, you get {E}. (You get an energy counter. Damage causes loss of life.)
Pay {E}{E}, Sacrifice Gonti's Machinations: Each opponent loses 3 life. You gain life equal to the life lost this way.

Curse of the Pierced Heart

Enchant player
At the beginning of enchanted player's upkeep, Curse of the Pierced Heart deals 1 damage to that player or a planeswalker that player controls.

Feedback

Enchant enchantment
At the beginning of the upkeep of enchanted enchantment's controller, Feedback deals 1 damage to that player.

Deathbringer Thoctar

Whenever another creature dies, you may put a +1/+1 counter on Deathbringer Thoctar.
Remove a +1/+1 counter from Deathbringer Thoctar: It deals 1 damage to any target.

Yawgmoth's Edict

Whenever an opponent casts a white spell, that player loses 1 life and you gain 1 life.

Dina, Soul Steeper

Whenever you gain life, each opponent loses 1 life.
{1}, Sacrifice another creature: Dina, Soul Steeper gets +X/+0 until end of turn, where X is the sacrificed creature's power.

Clawing Torment

Enchant artifact or creature
As long as enchanted permanent is a creature, it gets -1/-1 and can't block.
Enchanted permanent has "At the beginning of your upkeep, you lose 1 life."

Ob Nixilis, Captive Kingpin

Flying, trample
Whenever one or more opponents each lose exactly 1 life, put a +1/+1 counter on Ob Nixilis, Captive Kingpin. Exile the top card of your library. Until your next end step, you may play that card.

Heaven Sent

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I, II — Investigate.
III — Heaven Sent deals 1 damage to each opponent. Then if an opponent has 0 or less life, draw seven cards. Otherwise, exile Heaven Sent and you may cast it this turn.

Oath of Mages

At the beginning of each player's upkeep, that player chooses target player who has more life than they do and is their opponent. The first player may have Oath of Mages deal 1 damage to the second player.

Lambholt Ravager

Whenever you cast a noncreature spell, Lambholt Ravager deals 2 damage to each opponent.
Nightbound (If a player casts at least two spells during their own turn, it becomes day next turn.)

Lambholt Raconteur

Whenever you cast a noncreature spell, Lambholt Raconteur deals 1 damage to each opponent.
Daybound (If a player casts no spells during their own turn, it becomes night next turn.)

Lambholt Raconteur // Lambholt Ravager

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Reckless Assault

{1}, Pay 2 life: Reckless Assault deals 1 damage to any target.

Aether Sting

Whenever an opponent casts a creature spell, Aether Sting deals 1 damage to that player.

Tower of Calamities

{8}, {T}: Tower of Calamities deals 12 damage to target creature.

Etherwrought Page

At the beginning of your upkeep, choose one —
• You gain 2 life.
• Surveil 1. (Look at the top card of your library. You may put that card into your graveyard.)
• Each opponent loses 1 life.

Pillory of the Sleepless

Enchant creature
Enchanted creature can't attack or block.
Enchanted creature has "At the beginning of your upkeep, you lose 1 life."

Drana's Emissary

Flying
At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Cindervines

Whenever an opponent casts a noncreature spell, Cindervines deals 1 damage to that player.
{1}, Sacrifice Cindervines: Destroy target artifact or enchantment. Cindervines deals 2 damage to that permanent's controller.

Mardu Shadowspear

Whenever Mardu Shadowspear attacks, each opponent loses 1 life.
Dash {1}{B} (You may cast this spell for its dash cost. If you do, it gains haste, and it's returned from the battlefield to its owner's hand at the beginning of the next end step.)

Missy

Whenever another nonartifact creature dies, return it to the battlefield under your control face down and tapped. It's a 2/2 Cyberman artifact creature.
At the beginning of your end step, each opponent faces a villainous choice — Each artifact creature you control deals 1 damage to that opponent, or you draw a card and chaos ensues.

Wispdrinker Vampire

Flying
Whenever another creature you control with power 2 or less enters, each opponent loses 1 life and you gain 1 life.
{5}{W}{B}: Creatures you control with power 2 or less gain deathtouch and lifelink until end of turn.

Enslave

Enchant creature
You control enchanted creature.
At the beginning of your upkeep, enchanted creature deals 1 damage to its owner.

Numbing Dose

Enchant artifact or creature
Enchanted permanent doesn't untap during its controller's untap step.
At the beginning of the upkeep of enchanted permanent's controller, that player loses 1 life.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Gimli, Counter of Kills

Trample
Whenever a creature an opponent controls dies, Gimli, Counter of Kills deals 1 damage to that creature's controller.

Tunneling Geopede

Landfall — Whenever a land you control enters, Tunneling Geopede deals 1 damage to each opponent.

Flameblade Angel

Flying
Whenever a source an opponent controls deals damage to you or a permanent you control, you may have Flameblade Angel deal 1 damage to that source's controller.

Triskaidekaphobia

At the beginning of your upkeep, choose one —
• Each player with exactly 13 life loses the game, then each player gains 1 life.
• Each player with exactly 13 life loses the game, then each player loses 1 life.

Disciples of the Inferno

Prowess (Whenever you cast a noncreature spell, this creature gets +1/+1 until end of turn.)
If a noncreature source you control would deal damage to a creature, battle, or opponent, it deals that much damage plus 2 instead.

Invasion of Regatha

(As a Siege enters, choose an opponent to protect it. You and others can attack it. When it's defeated, exile it, then cast it transformed.)
When Invasion of Regatha enters, it deals 4 damage to another target battle or opponent and 1 damage to up to one target creature.

Invasion of Regatha // Disciples of the Inferno

Daunting Defender

If a source would deal damage to a Cleric creature you control, prevent 1 of that damage.

Hissing Miasma

Whenever a creature attacks you, its controller loses 1 life.

Shivan Gorge

{T}: Add {C}.
{2}{R}, {T}: Shivan Gorge deals 1 damage to each opponent.

Rampaging Ferocidon

Menace
Players can't gain life.
Whenever another creature enters, Rampaging Ferocidon deals 1 damage to that creature's controller.

Relic Bind

Enchant artifact an opponent controls
Whenever enchanted artifact becomes tapped, choose one —
• Relic Bind deals 1 damage to target player or planeswalker.
• Target player gains 1 life.

Urborg Stalker

At the beginning of each player's upkeep, if that player controls a nonblack, nonland permanent, Urborg Stalker deals 1 damage to that player.

Blood Reckoning

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life.

Haunting Wind

Whenever an artifact becomes tapped or a player activates an artifact's ability without {T} in its activation cost, Haunting Wind deals 1 damage to that artifact's controller.

Gibbering Descent

At the beginning of each player's upkeep, that player loses 1 life and discards a card.
Hellbent — Skip your upkeep step if you have no cards in hand.
Madness {2}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Warlock Class

(Gain the next level as a sorcery to add its ability.)
At the beginning of your end step, if a creature died this turn, each opponent loses 1 life.
{1}{B}: Level 2
When this Class becomes level 2, look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.
{6}{B}: Level 3
At the beginning of your end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Heat of Battle

Whenever a creature blocks, Heat of Battle deals 1 damage to that creature's controller.

Spiteflame Witch

Orbs of Warding

You have hexproof. (You can't be the target of spells or abilities your opponents control.)
If a creature would deal damage to you, prevent 1 of that damage.

Agent of Masks

At the beginning of your upkeep, each opponent loses 1 life. You gain life equal to the life lost this way.

Shepherd of Rot

{T}: Each player loses 1 life for each Zombie on the battlefield.

Grim Guardian

Constellation — Whenever Grim Guardian or another enchantment you control enters, each opponent loses 1 life.

Infectious Curse

Enchant player
Spells you cast that target enchanted player cost {1} less to cast.
At the beginning of enchanted player's upkeep, that player loses 1 life and you gain 1 life.

Accursed Witch

Spells your opponents cast that target Accursed Witch cost {1} less to cast.
When Accursed Witch dies, return it to the battlefield transformed under your control attached to target opponent.

Accursed Witch // Infectious Curse

Lim-Dûl's Hex

At the beginning of your upkeep, for each player, Lim-Dûl's Hex deals 1 damage to that player unless they pay {B} or {3}.

Caltrops

Whenever a creature attacks, Caltrops deals 1 damage to it.

Trespasser's Curse

Enchant player
Whenever a creature enchanted player controls enters, that player loses 1 life and you gain 1 life.

Carnage Gladiator

Whenever a creature blocks, that creature's controller loses 1 life.
{1}{B}{R}: Regenerate Carnage Gladiator.

Collapsing Borders

Domain — At the beginning of each player's upkeep, that player gains 1 life for each basic land type among lands they control. Then Collapsing Borders deals 3 damage to that player.

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

Subversion

Retreat to Hagra

Landfall — Whenever a land you control enters, choose one —
• Target creature gets +1/+0 and gains deathtouch until end of turn.
• Each opponent loses 1 life and you gain 1 life.

Raka Sanctuary

At the beginning of your upkeep, if you control a white or blue permanent, Raka Sanctuary deals 1 damage to target creature. If you control a white permanent and a blue permanent, Raka Sanctuary deals 3 damage instead.

Soul Enervation

Flash
When Soul Enervation enters, target creature gets -4/-4 until end of turn.
Whenever one or more creature cards leave your graveyard, each opponent loses 1 life and you gain 1 life.

Patron of the Nezumi

Rat offering (You may cast this spell any time you could cast an instant by sacrificing a Rat and paying the difference in mana costs between this and the sacrificed Rat. Mana cost includes color.)
Whenever a permanent is put into an opponent's graveyard, that player loses 1 life.

Commander Mustard

Vigilance
Other Soldiers you control have vigilance, trample, and haste.
{2}{R}{W}: Until end of turn, Soldiers you control gain "Whenever this creature attacks, it deals 1 damage to defending player."

Mount Doom

{T}, Pay 1 life: Add {B} or {R}.
{1}{B}{R}, {T}: Mount Doom deals 1 damage to each opponent.
{5}{B}{R}, {T}, Sacrifice Mount Doom and a legendary artifact: Choose up to two creatures, then destroy the rest. Activate only as a sorcery.

Valkmira, Protector's Shield

If a source an opponent controls would deal damage to you or a permanent you control, prevent 1 of that damage.
Whenever you or another permanent you control becomes the target of a spell or ability an opponent controls, counter that spell or ability unless its controller pays {1}.

Reidane, God of the Worthy

Flying, vigilance
Snow lands your opponents control enter tapped.
Noncreature spells your opponents cast with mana value 4 or greater cost {2} more to cast.

Reidane, God of the Worthy // Valkmira, Protector's Shield

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Smoldering Tar

At the beginning of your upkeep, target player loses 1 life.
Sacrifice Smoldering Tar: It deals 4 damage to target creature. Activate only as a sorcery.