Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Ob Nixilis of the Black Oath

+2: Each opponent loses 1 life. You gain life equal to the life lost this way.
−2: Create a 5/5 black Demon creature token with flying. You lose 2 life.
−8: You get an emblem with "{1}{B}, Sacrifice a creature: You gain X life and draw X cards, where X is the sacrificed creature's power."
Ob Nixilis of the Black Oath can be your commander.

Kokusho, the Evening Star

Flying
When Kokusho dies, each opponent loses 5 life. You gain life equal to the life lost this way.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Umezawa's Jitte

Whenever equipped creature deals combat damage, put two charge counters on Umezawa's Jitte.
Remove a charge counter from Umezawa's Jitte: Choose one —
• Equipped creature gets +2/+2 until end of turn.
• Target creature gets -1/-1 until end of turn.
• You gain 2 life.
Equip {2}

Servant of Tymaret

Inspired — Whenever this creature becomes untapped, each opponent loses 1 life. You gain life equal to the life lost this way.
{2}{B}: Regenerate this creature.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: This artifact deals 50 damage to any target.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Chancellor of the Dross

You may reveal this card from your opening hand. If you do, at the beginning of the first upkeep, each opponent loses 3 life, then you gain life equal to the life lost this way.
Flying, lifelink

Twilight Prophet

Flying
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your upkeep, if you have the city's blessing, reveal the top card of your library and put it into your hand. Each opponent loses X life and you gain X life, where X is that card's mana value.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Blood Tribute

Kicker—Tap an untapped Vampire you control. (You may tap a Vampire you control in addition to any other costs as you cast this spell.)
Target opponent loses half their life, rounded up. If this spell was kicked, you gain life equal to the life lost this way.

Soul Feast

Target player loses 4 life and you gain 4 life.

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on this enchantment. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if this enchantment has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Expedition Map

{2}, {T}, Sacrifice this artifact: Search your library for a land card, reveal it, put it into your hand, then shuffle.

Tendrils of Corruption

Tendrils of Corruption deals X damage to target creature and you gain X life, where X is the number of Swamps you control.

Battle at the Bridge

Improvise (Your artifacts can help cast this spell. Each artifact you tap after you're done activating mana abilities pays for {1}.)
Target creature gets -X/-X until end of turn. You gain X life.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Sorin's Vengeance

Sorin's Vengeance deals 10 damage to target player or planeswalker and you gain 10 life.

Swallowing Plague

Swallowing Plague deals X damage to target creature and you gain X life.

Vraska's Contempt

Exile target creature or planeswalker. You gain 2 life.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Curse of Vengeance

Enchant player
Whenever enchanted player casts a spell, put a spite counter on this Aura.
When enchanted player loses the game, you gain X life and draw X cards, where X is the number of spite counters on this Aura.

Syndicate Enforcer

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)

Covenant of Blood

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Covenant of Blood deals 4 damage to any target and you gain 4 life.

Whip of Erebos

Creatures you control have lifelink.
{2}{B}{B}, {T}: Return target creature card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step. If it would leave the battlefield, exile it instead of putting it anywhere else. Activate only as a sorcery.

Curse of Fool's Wisdom

Enchant player
Whenever enchanted player draws a card, they lose 2 life and you gain 2 life.
Madness {3}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Kalitas, Traitor of Ghet

Lifelink
If a nontoken creature an opponent controls would die, instead exile that card and create a 2/2 black Zombie creature token.
{2}{B}, Sacrifice another Vampire or Zombie: Put two +1/+1 counters on Kalitas.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Gilded Lotus

Extraplanar Lens

Imprint — When this artifact enters, you may exile target land you control.
Whenever a land with the same name as the exiled card is tapped for mana, its controller adds one mana of any type that land produced.

Noxious Gearhulk

Menace
When this creature enters, you may destroy another target creature. If a creature is destroyed this way, you gain life equal to its toughness.

Essence Harvest

Target player loses X life and you gain X life, where X is the greatest power among creatures you control.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Caged Sun

As this artifact enters, choose a color.
Creatures you control of the chosen color get +1/+1.
Whenever a land's ability causes you to add one or more mana of the chosen color, add an additional one mana of that color.

Darksteel Plate

Indestructible
Equipped creature has indestructible.
Equip {2}

Needlebite Trap

If an opponent gained life this turn, you may pay {B} rather than pay this spell's mana cost.
Target player loses 5 life and you gain 5 life.

Simulacrum

You gain life equal to the damage dealt to you this turn. Simulacrum deals damage to target creature you control equal to the damage dealt to you this turn.

Tower of Eons

Miren, the Moaning Well

{T}: Add {C}.
{3}, {T}, Sacrifice a creature: You gain life equal to the sacrificed creature's toughness.

Krav, the Unredeemed

Partner with Regna, the Redeemer (When this creature enters, target player may put Regna into their hand from their library, then shuffle.)
{B}, Sacrifice X creatures: Target player draws X cards and gains X life. Put X +1/+1 counters on Krav.

Suffer the Past

Exile X target cards from target player's graveyard. For each card exiled this way, that player loses 1 life and you gain 1 life.

Consume Spirit

Spend only black mana on X.
Consume Spirit deals X damage to any target and you gain X life.

Cavalier of Night

Lifelink
When this creature enters, you may sacrifice another creature. When you do, destroy target creature an opponent controls.
When this creature dies, return target creature card with mana value 3 or less from your graveyard to the battlefield.

Thran Dynamo

Corrupt

Corrupt deals damage to any target equal to the number of Swamps you control. You gain life equal to the damage dealt this way.

Pristine Talisman

Erebos's Intervention

Choose one —
• Target creature gets -X/-X until end of turn. You gain X life.
• Exile up to twice X target cards from graveyards.

Blood Tithe

Each opponent loses 3 life. You gain life equal to the life lost this way.

Pontiff of Blight

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Other creatures you control have extort. (If a creature has multiple instances of extort, each triggers separately.)

Drain Life

Spend only black mana on X.
Drain Life deals X damage to any target. You gain life equal to the damage dealt, but not more life than the player's life total before the damage was dealt, the planeswalker's loyalty before the damage was dealt, or the creature's toughness.

Basilica Screecher

Flying
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Soul Burn

Spend only black and/or red mana on X.
Soul Burn deals X damage to any target. You gain life equal to the damage dealt, but not more than the amount of {B} spent on X, the player's life total before the damage was dealt, the planeswalker's loyalty before the damage was dealt, or the creature's toughness.

Snow-Covered Swamp

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

Swift End

Destroy target creature or planeswalker. You lose 2 life. (Then exile this card. You may cast the creature later from exile.)

Murderous Rider

Lifelink
When this creature dies, put it on the bottom of its owner's library.

Murderous Rider // Swift End

Polluted Bonds

Whenever a land an opponent controls enters, that player loses 2 life and you gain 2 life.

Hammer of Nazahn

Whenever Hammer of Nazahn or another Equipment you control enters, you may attach that Equipment to target creature you control.
Equipped creature gets +2/+0 and has indestructible.
Equip {4}

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Mindcrank

Whenever an opponent loses life, that player mills that many cards. (Damage causes loss of life.)

Thrull Parasite

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
{T}, Pay 2 life: Remove a counter from target nonland permanent.

Sol Ring

Gray Merchant of Asphodel

When this creature enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)