Sign in Blood

Target player draws two cards and loses 2 life.

Dying Wish

Enchant creature you control
When enchanted creature dies, target player loses X life and you gain X life, where X is its power.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Lich's Mastery

Hexproof
You can't lose the game.
Whenever you gain life, draw that many cards.
Whenever you lose life, for each 1 life you lost, exile a permanent you control or a card from your hand or graveyard.
When Lich's Mastery leaves the battlefield, you lose the game.

Dark Ritual

Severed Strands

As an additional cost to cast this spell, sacrifice a creature.
You gain life equal to the sacrificed creature's toughness. Destroy target creature an opponent controls.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Kokusho, the Evening Star

Flying
When Kokusho dies, each opponent loses 5 life. You gain life equal to the life lost this way.

Essence Harvest

Target player loses X life and you gain X life, where X is the greatest power among creatures you control.

Temporal Extortion

When you cast this spell, any player may pay half their life, rounded up. If a player does, counter Temporal Extortion.
Take an extra turn after this one.

Dread Shade

{B}: This creature gets +1/+1 until end of turn.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Swamp

Blood Artist

Whenever this creature or another creature dies, target player loses 1 life and you gain 1 life.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Ritual of Soot

Destroy all creatures with mana value 3 or less.

Cabal Stronghold

{T}: Add {C}.
{3}, {T}: Add {B} for each basic Swamp you control.

Chalice of Death

Chalice of Life

{T}: You gain 1 life. Then if you have at least 10 life more than your starting life total, transform this artifact.

Chalice of Life // Chalice of Death

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

Tormented Hero

This creature enters tapped.
Heroic — Whenever you cast a spell that targets this creature, each opponent loses 1 life. You gain life equal to the life lost this way.