Go for the Throat

Twilight Prophet

Flying
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your upkeep, if you have the city's blessing, reveal the top card of your library and put it into your hand. Each opponent loses X life and you gain X life, where X is that card's mana value.

Davriel, Soul Broker

+1: Until your next turn, whenever an opponent attacks you and/or planeswalkers you control, they discard a card. If they can't, they sacrifice an attacking creature.
−2: Accept one of Davriel's offers, then accept one of Davriel's conditions.
−3: Target creature an opponent controls perpetually gets -3/-3.

Eliminate

Destroy target creature or planeswalker with mana value 3 or less.

Phyrexian Reclamation

{1}{B}, Pay 2 life: Return target creature card from your graveyard to your hand.

Soul Shatter

Each opponent sacrifices a creature or planeswalker with the highest mana value among creatures and planeswalkers they control.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

A-The Meathook Massacre

When The Meathook Massacre enters, each creature gets -X/-X until end of turn.
Whenever a creature you control dies, each opponent loses 1 life.

Fleshbag Marauder

When Fleshbag Marauder enters, each player sacrifices a creature of their choice.

Thoughtseize

Target player reveals their hand. You choose a nonland card from it. That player discards that card. You lose 2 life.

Priest of Forgotten Gods

{T}, Sacrifice two other creatures: Any number of target players each lose 2 life and sacrifice a creature of their choice. You add {B}{B} and draw a card.

Forgefire Automaton

Prototype {2}{B} — 3/2
At the beginning of your upkeep, return target creature card with power less than Forgefire Automaton's power from your graveyard to the battlefield. Its base power perpetually becomes equal to Forgefire Automaton's power.

Bastion of Remembrance

When Bastion of Remembrance enters, create a 1/1 white Human Soldier creature token.
Whenever a creature you control dies, each opponent loses 1 life and you gain 1 life.

Snow-Covered Swamp

Clattering Augur

Clattering Augur can't block.
When Clattering Augur enters, you draw a card and you lose 1 life.
{2}{B}{B}: Return Clattering Augur from your graveyard to your hand.

Extinction Event

Choose odd or even. Exile each creature with mana value of the chosen quality. (Zero is even.)

Massacre Wurm

When this creature enters, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Swift End

Destroy target creature or planeswalker. You lose 2 life. (Then exile this card. You may cast the creature later from exile.)

Murderous Rider

Lifelink
When Murderous Rider dies, put it on the bottom of its owner's library.

Murderous Rider // Swift End

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Skyclave Shade

Kicker {2}{B}
Skyclave Shade can't block.
If Skyclave Shade was kicked, it enters with two +1/+1 counters on it.
Landfall — Whenever a land you control enters, if Skyclave Shade is in your graveyard and it's your turn, you may cast it from your graveyard this turn.

Coldsteel Heart

Coldsteel Heart enters tapped.
As Coldsteel Heart enters, choose a color.
{T}: Add one mana of the chosen color.

Agadeem, the Undercrypt

As Agadeem, the Undercrypt enters, you may pay 3 life. If you don't, it enters tapped.
{T}: Add {B}.

Agadeem's Awakening

Return from your graveyard to the battlefield any number of target creature cards that each have a different mana value X or less.

Agadeem's Awakening // Agadeem, the Undercrypt

Persistent Specimen

{2}{B}: Return Persistent Specimen from your graveyard to the battlefield tapped.

Boneyard Aberration

When Boneyard Aberration dies, exile it. If you do, conjure three cards named Reassembling Skeleton into your graveyard.

Painful Bond

Draw two cards, then nonland cards in your hand with mana value 3 or less perpetually gain "When you cast this spell, you lose 1 life."

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Invoke Despair

Target opponent sacrifices a creature of their choice. If they can't, they lose 2 life and you draw a card. Then repeat this process for an enchantment and a planeswalker.

Dark Ritual

Dread Presence

Whenever a Swamp you control enters, choose one —
• You draw a card and you lose 1 life.
• Dread Presence deals 2 damage to any target and you gain 2 life.

Powerstone Fracture

As an additional cost to cast this spell, sacrifice an artifact or creature.
Destroy target creature or planeswalker.

Guardian Idol

Guardian Idol enters tapped.
{T}: Add {C}.
{2}: Guardian Idol becomes a 2/2 Golem artifact creature until end of turn.

Erebos's Intervention

Choose one —
• Target creature gets -X/-X until end of turn. You gain X life.
• Exile up to twice X target cards from graveyards.

A-Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life and scry 1.

Demon's Disciple

When Demon's Disciple enters, each player sacrifices a creature or planeswalker of their choice.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Midnight Reaper

Whenever a nontoken creature you control dies, this creature deals 1 damage to you and you draw a card.

Village Rites

As an additional cost to cast this spell, sacrifice a creature.
Draw two cards.

Hostile Negotiations

Exile the top three cards of your library in a face-down pile, then exile the top three cards of your library in another face-down pile. Look at the cards in each pile, then turn a pile of your choice face up. An opponent chooses one of those piles. Put that pile into your hand and the other into your graveyard. You lose 3 life.

Reassembling Skeleton

{1}{B}: Return this card from your graveyard to the battlefield tapped.

Soul Servitude

Target player sacrifices a nontoken creature. When they do, you may discard a card. If you do, conjure a duplicate of the sacrificed creature into your hand. It perpetually gains "You may spend mana as though it were mana of any color to cast this spell."

Sign in Blood

Target player draws two cards and loses 2 life.

Takenuma, Abandoned Mire

{T}: Add {B}.
Channel — {3}{B}, Discard Takenuma, Abandoned Mire: Mill three cards, then return a creature or planeswalker card from your graveyard to your hand. This ability costs {1} less to activate for each legendary creature you control.

Doom Blade

Jadar, Ghoulcaller of Nephalia

At the beginning of your end step, if you control no creatures with decayed, create a 2/2 black Zombie creature token with decayed. (It can't block. When it attacks, sacrifice it at end of combat.)

A-Blood Artist

Whenever Blood Artist or another creature dies, target opponent loses 1 life and you gain 1 life.

Xander's Wake

Whenever one or more creatures you control die, draft a card from Xander's Wake's spellbook. This ability triggers only once each turn.

Crux of Fate

Choose one —
• Destroy all Dragon creatures.
• Destroy all non-Dragon creatures.

Key to the Archive

Key to the Archive enters tapped.
When Key to the Archive enters, draft a card from Key to the Archive's spellbook, then discard a card.
{T}: Add two mana in any combination of colors.

Lolth, Spider Queen

Whenever a creature you control dies, put a loyalty counter on Lolth, Spider Queen.
0: You draw a card and you lose 1 life.
−3: Create two 2/1 black Spider creature tokens with menace and reach.
−8: You get an emblem with "Whenever an opponent is dealt combat damage by one or more creatures you control, if that player lost less than 8 life this turn, they lose life equal to the difference."

Rankle, Master of Pranks

Flying, haste
Whenever Rankle, Master of Pranks deals combat damage to a player, choose any number —
• Each player discards a card.
• Each player loses 1 life and draws a card.
• Each player sacrifices a creature of their choice.

Yawgmoth's Vile Offering

(You may cast a legendary sorcery only if you control a legendary creature or planeswalker.)
Put up to one target creature or planeswalker card from a graveyard onto the battlefield under your control. Destroy up to one target creature or planeswalker. Exile Yawgmoth's Vile Offering.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Blood on the Snow

Choose one —
• Destroy all creatures.
• Destroy all planeswalkers.
Then return a creature or planeswalker card with mana value X or less from your graveyard to the battlefield, where X is the amount of {S} spent to cast this spell. ({S} is mana from a snow source.)

Debt to the Kami

Choose one —
• Target opponent exiles a creature they control.
• Target opponent exiles an enchantment they control.

Morbid Opportunist

Whenever one or more other creatures die, draw a card. This ability triggers only once each turn.

Liliana, Dreadhorde General

Whenever a creature you control dies, draw a card.
+1: Create a 2/2 black Zombie creature token.
−4: Each player sacrifices two creatures of their choice.
−9: Each opponent chooses a permanent they control of each permanent type and sacrifices the rest.

Heartless Act

Choose one —
• Destroy target creature with no counters on it.
• Remove up to three counters from target creature.

Infernal Grasp

Destroy target creature. You lose 2 life.

Davriel's Withering

Target creature an opponent controls perpetually gets -1/-2.

Castle Locthwain

Castle Locthwain enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Plaguecrafter

When Plaguecrafter enters, each player sacrifices a creature or planeswalker of their choice. Each player who can't discards a card.

Crawling Barrens

{T}: Add {C}.
{4}: Put two +1/+1 counters on this land. Then you may have it become a 0/0 Elemental creature until end of turn. It's still a land.

Ayara, First of Locthwain

Whenever Ayara, First of Locthwain or another black creature you control enters, each opponent loses 1 life and you gain 1 life.
{T}, Sacrifice another black creature: Draw a card.

Kaya's Ghostform

Enchant creature or planeswalker you control
When enchanted permanent dies or is put into exile, return that card to the battlefield under your control.