Despark

Exile target permanent with mana value 4 or greater.

Tithe Drinker

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Leechridden Swamp

({T}: Add {B}.)
Leechridden Swamp enters tapped.
{B}, {T}: Each opponent loses 1 life. Activate only if you control two or more black permanents.

Ajani's Pridemate

Whenever you gain life, put a +1/+1 counter on Ajani's Pridemate.

Plains

Teysa, Envoy of Ghosts

Vigilance, protection from creatures
Whenever a creature deals combat damage to you, destroy that creature. Create a 1/1 white and black Spirit creature token with flying.

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Isareth the Awakener

Deathtouch
Whenever Isareth the Awakener attacks, you may pay {X}. When you do, return target creature card with mana value X from your graveyard to the battlefield with a corpse counter on it. If that creature would leave the battlefield, exile it instead of putting it anywhere else.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Drana's Emissary

Flying
At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Read the Bones

Scry 2, then draw two cards. You lose 2 life.

Ethereal Absolution

Creatures you control get +1/+1.
Creatures your opponents control get -1/-1.
{2}{W}{B}: Exile target card from an opponent's graveyard. If it was a creature card, you create a 1/1 white and black Spirit creature token with flying.

Oketra's Monument

White creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, create a 1/1 white Warrior creature token with vigilance.

One Thousand Lashes

Enchant creature
Enchanted creature can't attack or block, and its activated abilities can't be activated.
At the beginning of the upkeep of enchanted creature's controller, that player loses 1 life.

Alms of the Vein

Target opponent loses 3 life and you gain 3 life.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Temple of Silence

Temple of Silence enters tapped.
When Temple of Silence enters, scry 1.
{T}: Add {W} or {B}.

High Priest of Penance

Whenever High Priest of Penance is dealt damage, you may destroy target nonland permanent.

Kabira Crossroads

Kabira Crossroads enters tapped.
When Kabira Crossroads enters, you gain 2 life.
{T}: Add {W}.

Orzhova, the Church of Deals

{T}: Add {C}.
{3}{W}{B}, {T}: Target player loses 1 life and you gain 1 life.

Darksteel Ingot

Indestructible (Effects that say "destroy" don't destroy this artifact.)
{T}: Add one mana of any color.

Ill-Gotten Inheritance

At the beginning of your upkeep, Ill-Gotten Inheritance deals 1 damage to each opponent and you gain 1 life.
{5}{B}, Sacrifice Ill-Gotten Inheritance: It deals 4 damage to target opponent and you gain 4 life.

Basilica Bell-Haunt

When Basilica Bell-Haunt enters, each opponent discards a card and you gain 3 life.

Call to the Feast

Create three 1/1 white Vampire creature tokens with lifelink.

Font of Agonies

Whenever you pay life, put that many blood counters on Font of Agonies.
{1}{B}, Remove four blood counters from Font of Agonies: Destroy target creature.

Suture Priest

Whenever another creature you control enters, you may gain 1 life.
Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Serene Steward

Whenever you gain life, you may pay {W}. If you do, put a +1/+1 counter on target creature.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Go for the Throat

Kingpin's Pet

Flying
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)

Murder

Orzhov Signet

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Regal Bloodlord

Flying
At the beginning of each end step, if you gained life this turn, create a 1/1 black Bat creature token with flying.

Immortal Servitude

Return each creature card with mana value X from your graveyard to the battlefield.

Pillory of the Sleepless

Enchant creature
Enchanted creature can't attack or block.
Enchanted creature has "At the beginning of your upkeep, you lose 1 life."

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Felidar Sovereign

Vigilance, lifelink
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Gift of Orzhova

Enchant creature
Enchanted creature gets +1/+1 and has flying and lifelink.

Orzhov Basilica

Orzhov Basilica enters tapped.
When Orzhov Basilica enters, return a land you control to its owner's hand.
{T}: Add {W}{B}.

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter tapped.

Ritual of Rejuvenation

Revenge

Double your life total. Target opponent loses half their life, rounded up.

Revival

Return target creature card with mana value 3 or less from your graveyard to the battlefield.

Revival // Revenge

Soul Warden

Whenever another creature enters, you gain 1 life.

Death Grasp

Death Grasp deals X damage to any target. You gain X life.

Treasury Thrull

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever Treasury Thrull attacks, you may return target artifact, creature, or enchantment card from your graveyard to your hand.

Renewed Faith

You gain 6 life.
Cycling {1}{W} ({1}{W}, Discard this card: Draw a card.)
When you cycle Renewed Faith, you may gain 2 life.

Thriving Moor

Thriving Moor enters tapped. As it enters, choose a color other than black.
{T}: Add {B} or one mana of the chosen color.

Swamp

Blood Baron of Vizkopa

Lifelink, protection from white and from black
As long as you have 30 or more life and an opponent has 10 or less life, Blood Baron of Vizkopa gets +6/+6 and has flying.

Obzedat, Ghost Council

When Obzedat, Ghost Council enters, target opponent loses 2 life and you gain 2 life.
At the beginning of your end step, you may exile Obzedat. If you do, return it to the battlefield under its owner's control at the beginning of your next upkeep. It gains haste.

Consume

Target player sacrifices a creature with the greatest power among creatures they control. You gain life equal to its power.

Consecrate

Exile target card from a graveyard.
Draw a card.

Consecrate // Consume

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Trespasser's Curse

Enchant player
Whenever a creature enchanted player controls enters, that player loses 1 life and you gain 1 life.

Mortify

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Vampire Nighthawk

Dark Bargain

Look at the top three cards of your library. Put two of them into your hand and the other into your graveyard. Dark Bargain deals 2 damage to you.

Souls of the Faultless

Defender (This creature can't attack.)
Whenever Souls of the Faultless is dealt combat damage, you gain that much life and attacking player loses that much life.

Epicure of Blood

Whenever you gain life, each opponent loses 1 life.

Scoured Barrens

Scoured Barrens enters tapped.
When Scoured Barrens enters, you gain 1 life.
{T}: Add {W} or {B}.

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Torgaar, Famine Incarnate

As an additional cost to cast this spell, you may sacrifice any number of creatures. This spell costs {2} less to cast for each creature sacrificed this way.
When Torgaar, Famine Incarnate enters, up to one target player's life total becomes half their starting life total, rounded down.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Orzhov Guildgate

Orzhov Guildgate enters tapped.
{T}: Add {W} or {B}.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Alms Collector

Flash
If an opponent would draw two or more cards, instead you and that player each draw a card.

Soul of Eternity

Soul of Eternity's power and toughness are each equal to your life total.
Encore {7}{W}{W} ({7}{W}{W}, Exile this card from your graveyard: For each opponent, create a token copy that attacks that opponent this turn if able. They gain haste. Sacrifice them at the beginning of the next end step. Activate only as a sorcery.)

Pontiff of Blight

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Other creatures you control have extort. (If a creature has multiple instances of extort, each triggers separately.)

Agent of Masks

At the beginning of your upkeep, each opponent loses 1 life. You gain life equal to the life lost this way.

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Final Payment

As an additional cost to cast this spell, pay 5 life or sacrifice a creature or enchantment.
Destroy target creature.

Thriving Heath

Thriving Heath enters tapped. As it enters, choose a color other than white.
{T}: Add {W} or one mana of the chosen color.