Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Garza's Assassin

Sacrifice Garza's Assassin: Destroy target nonblack creature.
Recover—Pay half your life, rounded up. (When another creature is put into your graveyard from the battlefield, you may pay half your life, rounded up. If you do, return this card from your graveyard to your hand. Otherwise, exile this card.)

Arcane Denial

Counter target spell. Its controller may draw up to two cards at the beginning of the next turn's upkeep.
You draw a card at the beginning of the next turn's upkeep.

Bedevil

Destroy target artifact, creature, or planeswalker.

City of Brass

Whenever City of Brass becomes tapped, it deals 1 damage to you.
{T}: Add one mana of any color.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Negate

Blood Crypt

({T}: Add {B} or {R}.)
As Blood Crypt enters, you may pay 2 life. If you don't, it enters tapped.

Mountain

Marsh Flats

{T}, Pay 1 life, Sacrifice Marsh Flats: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Scalding Tarn

{T}, Pay 1 life, Sacrifice Scalding Tarn: Search your library for an Island or Mountain card, put it onto the battlefield, then shuffle.

Watery Grave

({T}: Add {U} or {B}.)
As Watery Grave enters, you may pay 2 life. If you don't, it enters tapped.

Counterspell

Training Center

Training Center enters tapped unless you have two or more opponents.
{T}: Add {U} or {R}.

Necrogen Spellbomb

{B}, Sacrifice Necrogen Spellbomb: Target player discards a card.
{1}, Sacrifice Necrogen Spellbomb: Draw a card.

Stormcarved Coast

Stormcarved Coast enters tapped unless you control two or more other lands.
{T}: Add {U} or {R}.

Dragonskull Summit

Dragonskull Summit enters tapped unless you control a Swamp or a Mountain.
{T}: Add {B} or {R}.

Jack-o'-Lantern

{1}, {T}, Sacrifice Jack-o'-Lantern: Exile up to one target card from a graveyard. Draw a card.
{1}, Exile Jack-o'-Lantern from your graveyard: Add one mana of any color.

Midnight Reaper

Whenever a nontoken creature you control dies, Midnight Reaper deals 1 damage to you and you draw a card.

Stronghold Assassin

{T}, Sacrifice a creature: Destroy target nonblack creature.

Ashnod the Uncaring

Deathtouch
Whenever you activate an ability of an artifact or creature that isn't a mana ability, if one or more permanents were sacrificed to activate it, you may copy that ability. You may choose new targets for the copy. (Sacrificing an artifact for mana to activate an ability doesn't count.)

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

An Offer You Can't Refuse

Counter target noncreature spell. Its controller creates two Treasure tokens. (They're artifacts with "{T}, Sacrifice this artifact: Add one mana of any color.")

Skullclamp

Equipped creature gets +1/-1.
Whenever equipped creature dies, draw two cards.
Equip {1}

Arid Mesa

{T}, Pay 1 life, Sacrifice Arid Mesa: Search your library for a Mountain or Plains card, put it onto the battlefield, then shuffle.

Terminate

Destroy target creature. It can't be regenerated.

Abrade

Choose one —
• Abrade deals 3 damage to target creature.
• Destroy target artifact.

Executioner's Capsule

{1}{B}, {T}, Sacrifice Executioner's Capsule: Destroy target nonblack creature.

Disdainful Stroke

Counter target spell with mana value 4 or greater.

Soul-Guide Lantern

When Soul-Guide Lantern enters, exile target card from a graveyard.
{T}, Sacrifice Soul-Guide Lantern: Exile each opponent's graveyard.
{1}, {T}, Sacrifice Soul-Guide Lantern: Draw a card.

Morphic Pool

Morphic Pool enters tapped unless you have two or more opponents.
{T}: Add {U} or {B}.

Grim Haruspex

Morph {B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)
Whenever another nontoken creature you control dies, draw a card.

Fabled Passage

{T}, Sacrifice Fabled Passage: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle. Then if you control four or more lands, untap that land.

Countersquall

Counter target noncreature spell. Its controller loses 2 life.

Pointed Discussion

You draw two cards, lose 2 life, then create a Blood token. (It's an artifact with "{1}, {T}, Discard a card, Sacrifice this artifact: Draw a card.")

Wild Magic Surge

Destroy target permanent an opponent controls. Its controller reveals cards from the top of their library until they reveal a permanent card that shares a card type with that permanent. They put that card onto the battlefield and the rest on the bottom of their library in a random order.

Luxury Suite

Luxury Suite enters tapped unless you have two or more opponents.
{T}: Add {B} or {R}.

Fire Covenant

As an additional cost to cast this spell, pay X life.
Fire Covenant deals X damage divided as you choose among any number of target creatures.

Prismatic Vista

{T}, Pay 1 life, Sacrifice Prismatic Vista: Search your library for a basic land card, put it onto the battlefield, then shuffle.

Underground River

{T}: Add {C}.
{T}: Add {U} or {B}. Underground River deals 1 damage to you.

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Scarab of the Unseen

{T}, Sacrifice Scarab of the Unseen: Return all Auras attached to target permanent you own to their owners' hands. Draw a card at the beginning of the next turn's upkeep.

Fiery Islet

{T}, Pay 1 life: Add {U} or {R}.
{1}, {T}, Sacrifice Fiery Islet: Draw a card.

Falkenrath Pit Fighter

{1}{R}, Discard a card, Sacrifice a Vampire: Draw two cards. Activate only if an opponent lost life this turn.

Resculpt

Exile target artifact or creature. Its controller creates a 4/4 blue and red Elemental creature token.

Bloodstained Mire

{T}, Pay 1 life, Sacrifice Bloodstained Mire: Search your library for a Swamp or Mountain card, put it onto the battlefield, then shuffle.

Infernal Grasp

Destroy target creature. You lose 2 life.

Aether Spellbomb

{U}, Sacrifice Aether Spellbomb: Return target creature to its owner's hand.
{1}, Sacrifice Aether Spellbomb: Draw a card.

Bloodbat Summoner

Flying
At the beginning of combat on your turn, up to one target Blood token you control becomes a 2/2 black Bat creature with flying and haste in addition to its other types.

Voldaren Bloodcaster

Flying
Whenever Voldaren Bloodcaster or another nontoken creature you control dies, create a Blood token. (It's an artifact with "{1}, {T}, Discard a card, Sacrifice this artifact: Draw a card.")
Whenever you create a Blood token, if you control five or more Blood tokens, transform Voldaren Bloodcaster.

Voldaren Bloodcaster // Bloodbat Summoner

Rapid Hybridization

Destroy target creature. It can't be regenerated. That creature's controller creates a 3/3 green Frog Lizard creature token.

Flooded Strand

{T}, Pay 1 life, Sacrifice Flooded Strand: Search your library for a Plains or Island card, put it onto the battlefield, then shuffle.

Mana Confluence

{T}, Pay 1 life: Add one mana of any color.

Trail of Evidence

Whenever you cast an instant or sorcery spell, investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")

Scrabbling Claws

{T}: Target player exiles a card from their graveyard.
{1}, Sacrifice Scrabbling Claws: Exile target card from a graveyard. Draw a card.

Tarnished Citadel

{T}: Add {C}.
{T}: Add one mana of any color. Tarnished Citadel deals 3 damage to you.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Scroll of Avacyn

{1}, Sacrifice Scroll of Avacyn: Draw a card. If you control an Angel, you gain 5 life.

Sol Ring

Mishra's Bauble

{T}, Sacrifice Mishra's Bauble: Look at the top card of target player's library. Draw a card at the beginning of the next turn's upkeep.

Wooded Foothills

{T}, Pay 1 life, Sacrifice Wooded Foothills: Search your library for a Mountain or Forest card, put it onto the battlefield, then shuffle.

Verdant Catacombs

{T}, Pay 1 life, Sacrifice Verdant Catacombs: Search your library for a Swamp or Forest card, put it onto the battlefield, then shuffle.

Phyrexian Furnace

{T}: Exile the bottom card of target player's graveyard.
{1}, Sacrifice Phyrexian Furnace: Exile target card from a graveyard. Draw a card.

Island

Conjurer's Bauble

{T}, Sacrifice Conjurer's Bauble: Put up to one target card from your graveyard on the bottom of your library. Draw a card.

Pyrite Spellbomb

{R}, Sacrifice Pyrite Spellbomb: It deals 2 damage to any target.
{1}, Sacrifice Pyrite Spellbomb: Draw a card.

Strefan, Maurer Progenitor

Flying
At the beginning of your end step, create a Blood token for each player who lost life this turn.
Whenever Strefan attacks, you may sacrifice two Blood tokens. If you do, you may put a Vampire card from your hand onto the battlefield tapped and attacking. It gains indestructible until end of turn.

Xander's Lounge

({T}: Add {U}, {B}, or {R}.)
Xander's Lounge enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Swamp

Goblin Engineer

When Goblin Engineer enters, you may search your library for an artifact card, put it into your graveyard, then shuffle.
{R}, {T}, Sacrifice an artifact: Return target artifact card with mana value 3 or less from your graveyard to the battlefield.

Delay

Counter target spell. If the spell is countered this way, exile it with three time counters on it instead of putting it into its owner's graveyard. If it doesn't have suspend, it gains suspend. (At the beginning of its owner's upkeep, they remove a time counter. When the last is removed, they may play it without paying its mana cost. If it's a creature, it has haste.)

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Steam Vents

({T}: Add {U} or {R}.)
As Steam Vents enters, you may pay 2 life. If you don't, it enters tapped.

Orazca Relic

Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
{T}: Add {C}.
{T}, Sacrifice Orazca Relic: You gain 3 life and draw a card. Activate only if you have the city's blessing.

Alchemist's Apprentice

Sacrifice Alchemist's Apprentice: Draw a card.

Fulminator Mage

Sacrifice Fulminator Mage: Destroy target nonbasic land.

Urza's Bauble

{T}, Sacrifice Urza's Bauble: Look at a card at random in target player's hand. You draw a card at the beginning of the next turn's upkeep.

Sulfur Falls

Sulfur Falls enters tapped unless you control an Island or a Mountain.
{T}: Add {U} or {R}.

Grim Hireling

Whenever one or more creatures you control deal combat damage to a player, create two Treasure tokens.
{B}, Sacrifice X Treasures: Target creature gets -X/-X until end of turn. Activate only as a sorcery.

Arterial Alchemy

When Arterial Alchemy enters, create a Blood token for each opponent you have. (It's an artifact with "{1}, {T}, Discard a card, Sacrifice this artifact: Draw a card.")
Blood tokens you control are Equipment in addition to their other types and have "Equipped creature gets +2/+0" and equip {2}.

Vampire's Kiss

Target player loses 2 life and you gain 2 life. Create two Blood tokens. (They're artifacts with "{1}, {T}, Discard a card, Sacrifice this artifact: Draw a card.")

Shipwreck Marsh

Shipwreck Marsh enters tapped unless you control two or more other lands.
{T}: Add {U} or {B}.

Bloodtithe Harvester

When Bloodtithe Harvester enters, create a Blood token. (It's an artifact with "{1}, {T}, Discard a card, Sacrifice this artifact: Draw a card.")
{T}, Sacrifice Bloodtithe Harvester: Target creature gets -X/-X until end of turn, where X is twice the number of Blood tokens you control. Activate only as a sorcery.

Insolent Neonate

Menace (This creature can't be blocked except by two or more creatures.)
Discard a card, Sacrifice Insolent Neonate: Draw a card.

Burnished Hart

{3}, Sacrifice Burnished Hart: Search your library for up to two basic land cards, put them onto the battlefield tapped, then shuffle.

Dauthi Voidwalker

Shadow (This creature can block or be blocked by only creatures with shadow.)
If a card would be put into an opponent's graveyard from anywhere, instead exile it with a void counter on it.
{T}, Sacrifice Dauthi Voidwalker: Choose an exiled card an opponent owns with a void counter on it. You may play it this turn without paying its mana cost.

Shivan Reef

{T}: Add {C}.
{T}: Add {U} or {R}. Shivan Reef deals 1 damage to you.

Polluted Delta

{T}, Pay 1 life, Sacrifice Polluted Delta: Search your library for an Island or Swamp card, put it onto the battlefield, then shuffle.

Pongify

Destroy target creature. It can't be regenerated. Its controller creates a 3/3 green Ape creature token.

Misty Rainforest

{T}, Pay 1 life, Sacrifice Misty Rainforest: Search your library for a Forest or Island card, put it onto the battlefield, then shuffle.

Goblin Cratermaker

{1}, Sacrifice Goblin Cratermaker: Choose one —
• Goblin Cratermaker deals 2 damage to target creature.
• Destroy target colorless nonland permanent.

Haunted Ridge

Haunted Ridge enters tapped unless you control two or more other lands.
{T}: Add {B} or {R}.

Lodestone Bauble

{1}, {T}, Sacrifice Lodestone Bauble: Put up to four target basic land cards from a player's graveyard on top of their library in any order. That player draws a card at the beginning of the next turn's upkeep.

Sulfurous Springs

{T}: Add {C}.
{T}: Add {B} or {R}. Sulfurous Springs deals 1 damage to you.

Drowned Catacomb

Drowned Catacomb enters tapped unless you control an Island or a Swamp.
{T}: Add {U} or {B}.

Mindslaver

{4}, {T}, Sacrifice Mindslaver: You control target player during that player's next turn. (You see all cards that player could see and make all decisions for the player.)

Professional Face-Breaker

Menace
Whenever one or more creatures you control deal combat damage to a player, create a Treasure token.
Sacrifice a Treasure: Exile the top card of your library. You may play that card this turn.