Phyrexian Etchings

Cumulative upkeep {B} (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
At the beginning of your end step, draw a card for each age counter on this enchantment.
When this enchantment is put into a graveyard from the battlefield, you lose 2 life for each age counter on it.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Barren Moor

This land enters tapped.
{T}: Add {B}.
Cycling {B} ({B}, Discard this card: Draw a card.)

Bellowing Mauler

At the beginning of your end step, each player loses 4 life unless they sacrifice a nontoken creature of their choice.

Bojuka Bog

This land enters tapped.
When this land enters, exile target player's graveyard.
{T}: Add {B}.

Hand of Vecna

At the beginning of combat on your turn, equipped creature or a creature you control named Vecna gets +X/+X until end of turn, where X is the number of cards in your hand.
Equip—Pay 1 life for each card in your hand.
Equip {2}

Seizan, Perverter of Truth

At the beginning of each player's upkeep, that player loses 2 life and draws two cards.

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Kiku, Night's Flower

{2}{B}{B}, {T}: Target creature deals damage to itself equal to its power.

Thrashing Mudspawn

Whenever this creature is dealt damage, you lose that much life.
Morph {1}{B}{B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Imp's Mischief

Change the target of target spell with a single target. You lose life equal to that spell's mana value.

Serpent Warrior

When this creature enters, you lose 3 life.

Herald of Torment

Bestow {3}{B}{B} (If you cast this card for its bestow cost, it's an Aura spell with enchant creature. It becomes a creature again if it's not attached to a creature.)
Flying
At the beginning of your upkeep, you lose 1 life.
Enchanted creature gets +3/+3 and has flying.

Polluted Mire

This land enters tapped.
{T}: Add {B}.
Cycling {2} ({2}, Discard this card: Draw a card.)

Platinum Emperion

Your life total can't change. (You can't gain or lose life. You can't pay any amount of life except 0.)

Bellowing Saddlebrute

Raid — When this creature enters, you lose 4 life unless you attacked this turn.

Stunning Reversal

The next time you would lose the game this turn, instead draw seven cards and your life total becomes 1.
Exile Stunning Reversal.

Archdemon of Greed

Flying, trample
At the beginning of your upkeep, sacrifice a Human. If you can't, tap this creature and it deals 9 damage to you.

Ravenous Demon

Sacrifice a Human: Transform this creature. Activate only as a sorcery.

Ravenous Demon // Archdemon of Greed

Atrocious Experiment

Target player mills two cards, draws two cards, and loses 2 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Sarevok, Deathbringer

At the beginning of each player's end step, if no permanents left the battlefield this turn, that player loses X life, where X is Sarevok's power.
Choose a Background (You can have a Background as a second commander.)

Malakir Mire

Malakir Rebirth

Choose target creature. You lose 2 life. Until end of turn, that creature gains "When this creature dies, return it to the battlefield tapped under its owner's control."

Malakir Rebirth // Malakir Mire

Kezzerdrix

First strike
At the beginning of your upkeep, if your opponents control no creatures, this creature deals 4 damage to you.

Dakmor Salvage

This land enters tapped.
{T}: Add {B}.
Dredge 2 (If you would draw a card, you may mill two cards instead. If you do, return this card from your graveyard to your hand.)

Bellowing Fiend

Flying
Whenever this creature deals damage to a creature, this creature deals 3 damage to that creature's controller and 3 damage to you.

Toshiro Umezawa

Bushido 1 (Whenever this creature blocks or becomes blocked, it gets +1/+1 until end of turn.)
Whenever a creature an opponent controls dies, you may cast target instant card from your graveyard. If that spell would be put into a graveyard, exile it instead.

Doomsday

Search your library and graveyard for five cards and exile the rest. Put the chosen cards on top of your library in any order. You lose half your life, rounded up.

Stab Wound

Enchant creature
Enchanted creature gets -2/-2.
At the beginning of the upkeep of enchanted creature's controller, that player loses 2 life.

Spawn of Mayhem

Spectacle {1}{B}{B} (You may cast this spell for its spectacle cost rather than its mana cost if an opponent lost life this turn.)
Flying, trample
At the beginning of your upkeep, this creature deals 1 damage to each player. Then if you have 10 or less life, put a +1/+1 counter on this creature.

Phyrexian Gargantua

When this creature enters, you draw two cards and you lose 2 life.

Withercrown

Enchant creature
Enchanted creature has base power 0 and has "At the beginning of your upkeep, you lose 1 life unless you sacrifice this creature."

Lord of the Pit

Flying, trample
At the beginning of your upkeep, sacrifice a creature other than this creature. If you can't, this creature deals 7 damage to you.

Embalmed Brawler

Amplify 1 (As this creature enters, put a +1/+1 counter on it for each Zombie card you reveal in your hand.)
Whenever this creature attacks or blocks, you lose 1 life for each +1/+1 counter on it.

Lich's Mirror

If you would lose the game, instead shuffle your hand, your graveyard, and all permanents you own into your library, then draw seven cards and your life total becomes 20.

Eye of Vecna

When Eye of Vecna enters, you draw a card and you lose 2 life.
At the beginning of your upkeep, you may pay {2}. If you do, you draw a card and you lose 2 life.

Treacherous Blessing

When this enchantment enters, draw three cards.
Whenever you cast a spell, you lose 1 life.
When this enchantment becomes the target of a spell or ability, sacrifice it.

Ambition's Cost

You draw three cards and you lose 3 life.

Torment of Scarabs

Enchant player
At the beginning of enchanted player's upkeep, that player loses 3 life unless they sacrifice a nonland permanent of their choice or discard a card.

Spoils of the Vault

Choose a card name. Reveal cards from the top of your library until you reveal a card with that name, then put that card into your hand. Exile all other cards revealed this way, and you lose 1 life for each of the exiled cards.

Night's Whisper

Leechridden Swamp

({T}: Add {B}.)
This land enters tapped.
{B}, {T}: Each opponent loses 1 life. Activate only if you control two or more black permanents.

Blood Scrivener

If you would draw a card while you have no cards in hand, instead you draw two cards and you lose 1 life.

Demon's Due

Scry 2, then draw two cards. You lose 2 life.

Bitter Revelation

Look at the top four cards of your library. Put two of them into your hand and the rest into your graveyard. You lose 2 life.

Priest of the Blood Rite

When this creature enters, create a 5/5 black Demon creature token with flying.
At the beginning of your upkeep, you lose 2 life.

Graf Reaver

Exploit (When this creature enters, you may sacrifice a creature.)
When this creature exploits a creature, destroy target planeswalker.
At the beginning of your upkeep, this creature deals 1 damage to you.

Acererak the Archlich

When Acererak the Archlich enters, if you haven't completed Tomb of Annihilation, return Acererak the Archlich to its owner's hand and venture into the dungeon.
Whenever Acererak the Archlich attacks, for each opponent, you create a 2/2 black Zombie creature token unless that player sacrifices a creature of their choice.

Cruel Bargain

Draw four cards. You lose half your life, rounded up.

Dark Tutelage

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Soul Bleed

Enchant creature
At the beginning of the upkeep of enchanted creature's controller, that player loses 1 life.

Shadows of the Past

Whenever a creature dies, scry 1. (Look at the top card of your library. You may put that card on the bottom.)
{4}{B}: Each opponent loses 2 life and you gain 2 life. Activate only if there are four or more creature cards in your graveyard.

Pitiless Horde

At the beginning of your upkeep, you lose 2 life.
Dash {2}{B}{B} (You may cast this spell for its dash cost. If you do, it gains haste, and it's returned from the battlefield to its owner's hand at the beginning of the next end step.)

Dark Bargain

Look at the top three cards of your library. Put two of them into your hand and the other into your graveyard. Dark Bargain deals 2 damage to you.

Wretched Anurid

Whenever another creature enters, you lose 1 life.

Keen Duelist

At the beginning of your upkeep, you and target opponent each reveal the top card of your library. You each lose life equal to the mana value of the card revealed by the other player. You each put the card you revealed into your hand.

Sygg, River Cutthroat

At the beginning of each end step, if an opponent lost 3 or more life this turn, you may draw a card. (Damage causes loss of life.)

Wicked Pact

Destroy two target nonblack creatures. You lose 5 life.

Blessing of Leeches

Flash
Enchant creature
At the beginning of your upkeep, you lose 1 life.
{0}: Regenerate enchanted creature.

Scourge of Numai

At the beginning of your upkeep, you lose 2 life if you don't control an Ogre.

Ancient Craving

Lim-Dûl's Hex

At the beginning of your upkeep, for each player, this enchantment deals 1 damage to that player unless they pay {B} or {3}.

The Golden Throne

Arcane Life-support — If you would lose the game, instead exile The Golden Throne and your life total becomes 1.
A Thousand Souls Die Every Day — {T}, Sacrifice a creature: Add three mana in any combination of colors.

Sarcomancy

When this enchantment enters, create a 2/2 black Zombie creature token.
At the beginning of your upkeep, if there are no Zombies on the battlefield, this enchantment deals 1 damage to you.

Morinfen

Flying
Cumulative upkeep—Pay 1 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Hoarder's Greed

You lose 2 life and draw two cards, then clash with an opponent. If you win, repeat this process. (Each clashing player reveals the top card of their library, then puts that card on the top or bottom. A player wins if their card had a higher mana value.)

Funeral Rites

You draw two cards, lose 2 life, then mill two cards.

Deadly Dispute

As an additional cost to cast this spell, sacrifice an artifact or creature.
Draw two cards and create a Treasure token. (It's an artifact with "{T}, Sacrifice this token: Add one mana of any color.")

Dusk Legion Zealot

When this creature enters, you draw a card and you lose 1 life.

Vampire Lacerator

At the beginning of your upkeep, you lose 1 life unless an opponent has 10 or less life.

Takenuma, Abandoned Mire

{T}: Add {B}.
Channel — {3}{B}, Discard this card: Mill three cards, then return a creature or planeswalker card from your graveyard to your hand. This ability costs {1} less to activate for each legendary creature you control.

Rain of Daggers

Destroy all creatures target opponent controls. You lose 2 life for each creature destroyed this way.

Reaver Drone

Devoid (This card has no color.)
At the beginning of your upkeep, you lose 1 life unless you control another colorless creature.

Vampiric Spirit

Flying
When this creature enters, you lose 4 life.

Infernal Grasp

Destroy target creature. You lose 2 life.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Raving Oni-Slave

When this creature enters or leaves the battlefield, you lose 3 life if you don't control a Demon.

Fledgling Djinn

Flying
At the beginning of your upkeep, this creature deals 1 damage to you.

Castle Locthwain

This land enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Swamp

Profane Transfusion

Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.

Cosmic Horror

First strike
At the beginning of your upkeep, destroy this creature unless you pay {3}{B}{B}{B}. If this creature is destroyed this way, it deals 7 damage to you.

Cut of the Profits

Casualty 3 (As you cast this spell, you may sacrifice a creature with power 3 or greater. When you do, copy this spell.)
You draw X cards and you lose X life.

Piranha Marsh

This land enters tapped.
When this land enters, target player loses 1 life.
{T}: Add {B}.

Magus of the Mirror

{T}, Sacrifice this creature: Exchange life totals with target opponent. Activate only during your upkeep.

Mindwrack Demon

Flying, trample
When this creature enters, mill four cards.
Delirium — At the beginning of your upkeep, you lose 4 life unless there are four or more card types among cards in your graveyard.

Strongarm Tactics

Each player discards a card. Then each player who didn't discard a creature card this way loses 4 life.

Painful Lesson

Target player draws two cards and loses 2 life.

Triskaidekaphobia

At the beginning of your upkeep, choose one —
• Each player with exactly 13 life loses the game, then each player gains 1 life.
• Each player with exactly 13 life loses the game, then each player loses 1 life.

Gravepurge

Put any number of target creature cards from your graveyard on top of your library.
Draw a card.

Hideous End

Destroy target nonblack creature. Its controller loses 2 life.

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Mutilate

All creatures get -1/-1 until end of turn for each Swamp you control.

Chainer's Torment

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I, II — This Saga deals 2 damage to each opponent and you gain 2 life.
III — Create an X/X black Nightmare Horror creature token, where X is half your life total, rounded up. It deals X damage to you.

Liege of the Pit

Flying, trample
At the beginning of your upkeep, sacrifice a creature other than this creature. If you can't, this creature deals 7 damage to you.
Morph {B}{B}{B}{B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Flesh Reaver

Whenever this creature deals damage to a creature or opponent, this creature deals that much damage to you.

Xathrid Demon

Flying, trample
At the beginning of your upkeep, sacrifice a creature other than this creature, then each opponent loses life equal to the sacrificed creature's power. If you can't sacrifice a creature, tap this creature and you lose 7 life.

Ulcerate

Target creature gets -3/-3 until end of turn. You lose 3 life.

Nim Abomination

At the beginning of your end step, if this creature is untapped, you lose 3 life.

Phyrexian Delver

When this creature enters, return target creature card from your graveyard to the battlefield. You lose life equal to that card's mana value.

Fathom Fleet Boarder

When this creature enters, you lose 2 life unless you control another Pirate.