Lotho, Corrupt Shirriff

Whenever a player casts their second spell each turn, you lose 1 life and create a Treasure token. (It's an artifact with "{T}, Sacrifice this token: Add one mana of any color.")

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: This creature gets +1/+1 until end of turn.

Night's Whisper

Mister Negative

Vigilance, lifelink
Darkforce Inversion — When Mister Negative enters, you may exchange life totals with target opponent. If you lost life this way, draw that many cards.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to that card's mana value.

Ghostly Prison

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Tainted Remedy

If an opponent would gain life, that player loses that much life instead.

Marsh Flats

{T}, Pay 1 life, Sacrifice this land: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Enduring Tenacity

Whenever you gain life, target opponent loses that much life.
When Enduring Tenacity dies, if it was a creature, return it to the battlefield under its owner's control. It's an enchantment. (It's not a creature.)

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Scrubland

Loran of the Third Path

Vigilance
When Loran enters, destroy up to one target artifact or enchantment.
{T}: You and target opponent each draw a card.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Sign in Blood

Target player draws two cards and loses 2 life.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice this artifact: Draw a card.

The Soul Stone

Indestructible
{T}: Add {B}.
{6}{B}, {T}, Exile a creature you control: Harness The Soul Stone. (Once harnessed, its ∞ ability is active.)
∞ — At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.

Teleportation Circle

At the beginning of your end step, exile up to one target artifact or creature you control, then return that card to the battlefield under its owner's control.

Sol Ring

Orzhov Signet

Platinum Angel

Flying
You can't lose the game and your opponents can't win the game.

Children of Korlis

Sacrifice this creature: You gain life equal to the life you've lost this turn. (Damage causes loss of life.)

Blood Celebrant

{B}, Pay 1 life: Add one mana of any color.

Conjurer's Closet

At the beginning of your end step, you may exile target creature you control, then return that card to the battlefield under your control.

Grimclimb Pathway

Brightclimb Pathway

Brightclimb Pathway // Grimclimb Pathway

Eerie Interlude

Exile any number of target creatures you control. Return those cards to the battlefield under their owner's control at the beginning of the next end step.

The Book of Exalted Deeds

At the beginning of your end step, if you gained 3 or more life this turn, create a 3/3 white Angel creature token with flying.
{W}{W}{W}, {T}, Exile The Book of Exalted Deeds: Put an enlightened counter on target Angel. It gains "You can't lose the game and your opponents can't win the game." Activate only as a sorcery.

Phyrexian Unlife

You don't lose the game for having 0 or less life.
As long as you have 0 or less life, all damage is dealt to you as though its source had infect. (Damage is dealt to you in the form of poison counters.)

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Shattered Sanctum

This land enters tapped unless you control two or more other lands.
{T}: Add {W} or {B}.

Flicker of Fate

Exile target creature or enchantment, then return it to the battlefield under its owner's control.

Black Market Connections

At the beginning of your first main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It is every creature type.)

Avacyn's Memorial

Indestructible
Other legendary permanents you control have indestructible.

Delaying Shield

If damage would be dealt to you, put that many delay counters on this enchantment instead.
At the beginning of your upkeep, remove all delay counters from this enchantment. For each delay counter removed this way, you lose 1 life unless you pay {1}{W}.

Deadly Rollick

If you control a commander, you may cast this spell without paying its mana cost.
Exile target creature.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with this creature's toughness.

Soul Echo

This enchantment enters with X echo counters on it.
You don't lose the game for having 0 or less life.
At the beginning of your upkeep, sacrifice this enchantment if there are no echo counters on it. Otherwise, target opponent may choose that for each 1 damage that would be dealt to you until your next upkeep, you remove an echo counter from this enchantment instead.

Cloudsteel Kirin

Flying
Equipped creature has flying and "You can't lose the game and your opponents can't win the game."
Reconfigure {5} ({5}: Attach to target creature you control; or unattach from a creature. Reconfigure only as a sorcery. While attached, this isn't a creature.)

Solemnity

Players can't get counters.
Counters can't be put on artifacts, creatures, enchantments, or lands.

Isolated Chapel

This land enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Despark

Exile target permanent with mana value 4 or greater.

Avacyn, Angel of Hope

Flying, vigilance, indestructible
Other permanents you control have indestructible.

Phelia, Exuberant Shepherd

Flash
Whenever Phelia attacks, exile up to one other target nonland permanent. At the beginning of the next end step, return that card to the battlefield under its owner's control. If it entered under your control, put a +1/+1 counter on Phelia.

Plains

Command Tower

Herald of Eternal Dawn

Flash (You may cast this spell any time you could cast an instant.)
Flying
You can't lose the game and your opponents can't win the game.

Generous Gift

Destroy target permanent. Its controller creates a 3/3 green Elephant creature token.

Tainted Field

{T}: Add {C}.
{T}: Add {W} or {B}. Activate only if you control a Swamp.

Pact Weapon

As long as this Equipment is attached to a creature, you don't lose the game for having 0 or less life.
Whenever equipped creature attacks, draw a card and reveal it. The creature gets +X/+X until end of turn and you lose X life, where X is that card's mana value.
Equip—Discard a card.

Greed

Godless Shrine

({T}: Add {W} or {B}.)
As this land enters, you may pay 2 life. If you don't, it enters tapped.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Cloudshift

Exile target creature you control, then return that card to the battlefield under your control.

Swamp

Dark Confidant

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Esper Sentinel

Whenever an opponent casts their first noncreature spell each turn, draw a card unless that player pays {X}, where X is this creature's power.

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. This artifact deals 1 damage to you.

Gideon of the Trials

+1: Until your next turn, prevent all damage target permanent would deal.
0: Until end of turn, Gideon becomes a 4/4 Human Soldier creature with indestructible that's still a planeswalker. Prevent all damage that would be dealt to him this turn.
0: You get an emblem with "As long as you control a Gideon planeswalker, you can't lose the game and your opponents can't win the game."

Parker Luck

At the beginning of your end step, two target players each reveal the top card of their library. They each lose life equal to the mana value of the card revealed by the other player. Then they each put the card they revealed into their hand.

Flickerwisp

Flying
When this creature enters, exile another target permanent. Return that card to the battlefield under its owner's control at the beginning of the next end step.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Bojuka Bog

This land enters tapped.
When this land enters, exile target player's graveyard.
{T}: Add {B}.

Ephemerate

Exile target creature you control, then return it to the battlefield under its owner's control.
Rebound (If you cast this spell from your hand, exile it as it resolves. At the beginning of your next upkeep, you may cast this card from exile without paying its mana cost.)

Bleachbone Verge

{T}: Add {B}.
{T}: Add {W}. Activate only if you control a Plains or a Swamp.

Vault of Champions

This land enters tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Angel's Grace

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
You can't lose the game this turn and your opponents can't win the game this turn. Until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Thought Vessel

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Gwenom, Remorseless

Deathtouch, lifelink
Whenever Gwenom attacks, until end of turn, you may look at the top card of your library any time and you may play cards from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.