Bloodhall Priest

Whenever this creature enters or attacks, if you have no cards in hand, this creature deals 2 damage to any target.
Madness {1}{B}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Terminal Agony

Destroy target creature.
Madness {B}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Glint-Horn Buccaneer

Haste
Whenever you discard a card, this creature deals 1 damage to each opponent.
{1}{R}, Discard a card: Draw a card. Activate only if this creature is attacking.

Ivora, Insatiable Heir

Trample
When Ivora enters and whenever it deals combat damage to a player, create a Blood token. (It's an artifact with "{1}, {T}, Discard a card, Sacrifice this token: Draw a card.")
Whenever you discard a card, put a +1/+1 counter on Ivora.

Body Launderer

Deathtouch
Whenever another nontoken creature you control dies, this creature connives.
When this creature dies, return another target non-Rogue creature card with equal or lesser power from your graveyard to the battlefield.

Hobgoblin, Mantled Marauder

Flying, haste
Whenever you discard a card, Hobgoblin gets +2/+0 until end of turn.

Brallin, Skyshark Rider

Partner with Shabraz, the Skyshark (When this creature enters, target player may put Shabraz into their hand from their library, then shuffle.)
Whenever you discard a card, put a +1/+1 counter on Brallin and it deals 1 damage to each opponent.
{R}: Target Shark gains trample until end of turn.

Feast of Sanity

Whenever you discard a card, this enchantment deals 1 damage to any target and you gain 1 life.

Anje Falkenrath

Haste
{T}, Discard a card: Draw a card.
Whenever you discard a card, if it has madness, untap Anje Falkenrath.

Ultimate Green Goblin

At the beginning of your upkeep, discard a card, then create a Treasure token.
Mayhem {2}{B/R} (You may cast this card from your graveyard for {2}{B/R} if you discarded it this turn. Timing rules still apply.)