Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Culling Ritual

Destroy each nonland permanent with mana value 2 or less. Add {B} or {G} for each permanent destroyed this way.

Noxious Hatchling

Noxious Hatchling enters with four -1/-1 counters on it.
Wither (This deals damage to creatures in the form of -1/-1 counters.)
Whenever you cast a black spell, remove a -1/-1 counter from Noxious Hatchling.
Whenever you cast a green spell, remove a -1/-1 counter from Noxious Hatchling.

Devoted Druid

{T}: Add {G}.
Put a -1/-1 counter on Devoted Druid: Untap Devoted Druid.

Phyrexian Hydra

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
If damage would be dealt to Phyrexian Hydra, prevent that damage. Put a -1/-1 counter on Phyrexian Hydra for each 1 damage prevented this way.

Black Sun's Zenith

Put X -1/-1 counters on each creature. Shuffle Black Sun's Zenith into its owner's library.

Necroskitter

Wither (This deals damage to creatures in the form of -1/-1 counters.)
Whenever a creature an opponent controls with a -1/-1 counter on it dies, you may return that card to the battlefield under your control.

Crumbling Ashes

At the beginning of your upkeep, destroy target creature with a -1/-1 counter on it.

Hooded Blightfang

Deathtouch
Whenever a creature you control with deathtouch attacks, each opponent loses 1 life and you gain 1 life.
Whenever a creature you control with deathtouch deals damage to a planeswalker, destroy that planeswalker.

Dusk Urchins

Whenever Dusk Urchins attacks or blocks, put a -1/-1 counter on it.
When Dusk Urchins dies, draw a card for each -1/-1 counter on it.

Midnight Banshee

Wither (This deals damage to creatures in the form of -1/-1 counters.)
At the beginning of your upkeep, put a -1/-1 counter on each nonblack creature.

Elves of Deep Shadow

{T}: Add {B}. Elves of Deep Shadow deals 1 damage to you.

Quillspike

{B/G}, Remove a -1/-1 counter from a creature you control: Quillspike gets +3/+3 until end of turn.

Tainted Strike

Target creature gets +1/+0 and gains infect until end of turn. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Skinrender

When Skinrender enters, put three -1/-1 counters on target creature.

Ammit Eternal

Afflict 3 (Whenever this creature becomes blocked, defending player loses 3 life.)
Whenever an opponent casts a spell, put a -1/-1 counter on Ammit Eternal.
Whenever Ammit Eternal deals combat damage to a player, remove all -1/-1 counters from it.

Creakwood Liege

Other black creatures you control get +1/+1.
Other green creatures you control get +1/+1.
At the beginning of your upkeep, you may create a 1/1 black and green Worm creature token.

Evolution Sage

Landfall — Whenever a land you control enters, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Viridian Longbow

Equipped creature has "{T}: This creature deals 1 damage to any target."
Equip {3} ({3}: Attach to target creature you control. Equip only as a sorcery. This card enters unattached and stays on the battlefield if the creature leaves.)

Soul Snuffers

When Soul Snuffers enters, put a -1/-1 counter on each creature.

Grim Affliction

Put a -1/-1 counter on target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Serrated Arrows

Serrated Arrows enters with three arrowhead counters on it.
At the beginning of your upkeep, if there are no arrowhead counters on Serrated Arrows, sacrifice it.
{T}, Remove an arrowhead counter from Serrated Arrows: Put a -1/-1 counter on target creature.

Wickerbough Elder

Wickerbough Elder enters with a -1/-1 counter on it.
{G}, Remove a -1/-1 counter from Wickerbough Elder: Destroy target artifact or enchantment.

Flourishing Defenses

Whenever a -1/-1 counter is put on a creature, you may create a 1/1 green Elf Warrior creature token.

Cauldron of Souls

{T}: Choose any number of target creatures. Each of those creatures gains persist until end of turn. (When it dies, if it had no -1/-1 counters on it, return it to the battlefield under its owner's control with a -1/-1 counter on it.)

Contagion Engine

When Contagion Engine enters, put a -1/-1 counter on each creature target player controls.
{4}, {T}: Proliferate twice. (Choose any number of permanents and/or players, then give each another counter of each kind already there. Then do it again.)

Persist

Return target nonlegendary creature card from your graveyard to the battlefield with a -1/-1 counter on it.

Banewhip Punisher

When Banewhip Punisher enters, you may put a -1/-1 counter on target creature.
{B}, Sacrifice Banewhip Punisher: Destroy target creature that has a -1/-1 counter on it.

Abrupt Decay

This spell can't be countered.
Destroy target nonland permanent with mana value 3 or less.

Plumb the Forbidden

As an additional cost to cast this spell, you may sacrifice one or more creatures. When you do, copy this spell for each creature sacrificed this way.
You draw a card and you lose 1 life.

Splendid Agony

Distribute two -1/-1 counters among one or two target creatures.

Liliana, Death Wielder

+2: Put a -1/-1 counter on up to one target creature.
−3: Destroy target creature with a -1/-1 counter on it.
−10: Return all creature cards from your graveyard to the battlefield.

Despair

Aftermath (Cast this spell only from your graveyard. Then exile it.)
Until end of turn, creatures you control gain menace and "Whenever this creature deals combat damage to a player, that player discards a card."

Driven

Until end of turn, creatures you control gain trample and "Whenever this creature deals combat damage to a player, draw a card."

Driven // Despair

Generous Patron

When Generous Patron enters, support 2. (Put a +1/+1 counter on each of up to two other target creatures.)
Whenever you put one or more counters on a creature you don't control, draw a card.

Hapatra, Vizier of Poisons

Whenever Hapatra, Vizier of Poisons deals combat damage to a player, you may put a -1/-1 counter on target creature.
Whenever you put one or more -1/-1 counters on a creature, create a 1/1 green Snake creature token with deathtouch.

Liliana's Influence

Put a -1/-1 counter on each creature you don't control. You may search your library and/or graveyard for a card named Liliana, Death Wielder, reveal it, and put it into your hand. If you search your library this way, shuffle.

Chatterfang, Squirrel General

Forestwalk (This creature can't be blocked as long as defending player controls a Forest.)
If one or more tokens would be created under your control, those tokens plus that many 1/1 green Squirrel creature tokens are created instead.
{B}, Sacrifice X Squirrels: Target creature gets +X/-X until end of turn.

Skullclamp

Equipped creature gets +1/-1.
Whenever equipped creature dies, draw two cards.
Equip {1}

Deathrite Shaman

{T}: Exile target land card from a graveyard. Add one mana of any color.
{B}, {T}: Exile target instant or sorcery card from a graveyard. Each opponent loses 2 life.
{G}, {T}: Exile target creature card from a graveyard. You gain 2 life.

Seshiro the Anointed

Other Snake creatures you control get +2/+2.
Whenever a Snake you control deals combat damage to a player, you may draw a card.

Ohran Frostfang

Attacking creatures you control have deathtouch.
Whenever a creature you control deals combat damage to a player, draw a card.

Nest of Scarabs

Whenever you put one or more -1/-1 counters on a creature, create that many 1/1 black Insect creature tokens.

Contagion Clasp

When Contagion Clasp enters, put a -1/-1 counter on target creature.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

End-Raze Forerunners

Vigilance, trample, haste
When End-Raze Forerunners enters, other creatures you control get +2/+2 and gain vigilance and trample until end of turn.

Fynn, the Fangbearer

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Whenever a creature you control with deathtouch deals combat damage to a player, that player gets two poison counters. (A player with ten or more poison counters loses the game.)

Sudden Spoiling

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Until end of turn, creatures target player controls lose all abilities and have base power and toughness 0/2.

Shamanic Revelation

Draw a card for each creature you control.
Ferocious — You gain 4 life for each creature you control with power 4 or greater.

Incremental Blight

Put a -1/-1 counter on target creature, two -1/-1 counters on another target creature, and three -1/-1 counters on a third target creature.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Grasping Dunes

{T}: Add {C}.
{1}, {T}, Sacrifice Grasping Dunes: Put a -1/-1 counter on target creature. Activate only as a sorcery.

Glistening Oil

Enchant creature
Enchanted creature has infect.
At the beginning of your upkeep, put a -1/-1 counter on enchanted creature.
When Glistening Oil is put into a graveyard from the battlefield, return Glistening Oil to its owner's hand.

Chord of Calling

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Search your library for a creature card with mana value X or less, put it onto the battlefield, then shuffle.

Moldervine Reclamation

Whenever a creature you control dies, you gain 1 life and draw a card.

Decimator Beetle

When Decimator Beetle enters, put a -1/-1 counter on target creature you control.
Whenever Decimator Beetle attacks, remove a -1/-1 counter from target creature you control and put a -1/-1 counter on up to one target creature defending player controls.

Vraska, Swarm's Eminence

Whenever a creature you control with deathtouch deals damage to a player or planeswalker, put a +1/+1 counter on that creature.
−2: Create a 1/1 black Assassin creature token with deathtouch and "Whenever this creature deals damage to a planeswalker, destroy that planeswalker."

Ifnir Deadlands

{T}: Add {C}.
{T}, Pay 1 life: Add {B}.
{2}{B}{B}, {T}, Sacrifice a Desert: Put two -1/-1 counters on target creature an opponent controls. Activate only as a sorcery.

Casualties of War

Choose one or more —
• Destroy target artifact.
• Destroy target creature.
• Destroy target enchantment.
• Destroy target land.
• Destroy target planeswalker.

Obelisk Spider

Reach
Whenever Obelisk Spider deals combat damage to a creature, put a -1/-1 counter on that creature.
Whenever you put one or more -1/-1 counters on a creature, each opponent loses 1 life and you gain 1 life.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Zulaport Cutthroat

Whenever Zulaport Cutthroat or another creature you control dies, each opponent loses 1 life and you gain 1 life.

Harvest Season

Search your library for up to X basic land cards, where X is the number of tapped creatures you control, put those cards onto the battlefield tapped, then shuffle.

Blowfly Infestation

Whenever a creature dies, if it had a -1/-1 counter on it, put a -1/-1 counter on target creature.

Village Rites

As an additional cost to cast this spell, sacrifice a creature.
Draw two cards.

Golgari Charm

Choose one —
• All creatures get -1/-1 until end of turn.
• Destroy target enchantment.
• Regenerate each creature you control.

Poison-Tip Archer

Reach (This creature can block creatures with flying.)
Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Whenever another creature dies, each opponent loses 1 life.

Smell Fear

Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)
Target creature you control fights up to one target creature you don't control.

Channeler Initiate

When Channeler Initiate enters, put three -1/-1 counters on target creature you control.
{T}, Remove a -1/-1 counter from Channeler Initiate: Add one mana of any color.

Vhati il-Dal

{T}: Until end of turn, target creature has base power 1 or base toughness 1.

Vraska, Golgari Queen

+2: You may sacrifice another permanent. If you do, you gain 1 life and draw a card.
−3: Destroy target nonland permanent with mana value 3 or less.
−9: You get an emblem with "Whenever a creature you control deals combat damage to a player, that player loses the game."

Corrosive Mentor

Black creatures you control have wither. (They deal damage to creatures in the form of -1/-1 counters.)

Assassin's Trophy

Destroy target permanent an opponent controls. Its controller may search their library for a basic land card, put it onto the battlefield, then shuffle.

Carnifex Demon

Flying
Carnifex Demon enters with two -1/-1 counters on it.
{B}, Remove a -1/-1 counter from Carnifex Demon: Put a -1/-1 counter on each other creature.