Feast of Sanity

Whenever you discard a card, Feast of Sanity deals 1 damage to any target and you gain 1 life.

Mortiphobia

{1}{B}, Discard a card: Exile target card from a graveyard.
{1}{B}, Sacrifice Mortiphobia: Exile target card from a graveyard.

Dogged Pursuit

At the beginning of your end step, each opponent loses 1 life and you gain 1 life.

Assassinate

Deathspore Thallid

At the beginning of your upkeep, put a spore counter on Deathspore Thallid.
Remove three spore counters from Deathspore Thallid: Create a 1/1 green Saproling creature token.
Sacrifice a Saproling: Target creature gets -1/-1 until end of turn.

Swamp

Bushmeat Poacher

{1}, {T}, Sacrifice another creature: You gain life equal to the sacrificed creature's toughness. Draw a card.

Manalith

Faith of the Devoted

Whenever you cycle or discard a card, you may pay {1}. If you do, each opponent loses 2 life and you gain 2 life.

Gilt-Blade Prowler

{1}, {T}, Pay 1 life: Draw a card. Activate only if you've discarded a card this turn.

Skirge Familiar

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters the battlefield, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Mage Hunters' Onslaught

Destroy target creature or planeswalker.
Whenever a creature blocks this turn, its controller loses 1 life.

Skirsdag Supplicant

{B}, {T}, Discard a card: Each player loses 2 life.

Bag of Holding

Whenever you discard a card, exile that card from your graveyard.
{2}, {T}: Draw a card, then discard a card.
{4}, {T}, Sacrifice Bag of Holding: Return all cards exiled with Bag of Holding to their owner's hand.

Charcoal Diamond

Charcoal Diamond enters the battlefield tapped.
{T}: Add {B}.

Mortarpod

Living weapon (When this Equipment enters the battlefield, create a 0/0 black Phyrexian Germ creature token, then attach this to it.)
Equipped creature gets +0/+1 and has "Sacrifice this creature: This creature deals 1 damage to any target."
Equip {2}

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Daring Demolition

Staff of the Death Magus

Whenever you cast a black spell or a Swamp enters the battlefield under your control, you gain 1 life.

Dreadhorde Invasion

At the beginning of your upkeep, you lose 1 life and amass Zombies 1. (Put a +1/+1 counter on an Army you control. It's also a Zombie. If you don't control an Army, create a 0/0 black Zombie Army creature token first.)
Whenever a Zombie token you control with power 6 or greater attacks, it gains lifelink until end of turn.

Vendetta

Destroy target nonblack creature. It can't be regenerated. You lose life equal to that creature's toughness.

Urborg Syphon-Mage

{2}{B}, {T}, Discard a card: Each other player loses 2 life. You gain life equal to the life lost this way.

Spinning Wheel

{T}: Add one mana of any color.
{5}, {T}: Tap target creature.

Mutual Destruction

This spell has flash as long as you control a permanent with flash.
As an additional cost to cast this spell, sacrifice a creature.
Destroy target creature.

Viscera Seer

Sacrifice a creature: Scry 1. (Look at the top card of your library. You may put that card on the bottom of your library.)

Magus of the Mirror

{T}, Sacrifice Magus of the Mirror: Exchange life totals with target opponent. Activate only during your upkeep.

Ghastly Demise

Destroy target nonblack creature if its toughness is less than or equal to the number of cards in your graveyard.

Infectious Horror

Whenever Infectious Horror attacks, each opponent loses 2 life.

Impale

Flay Essence

Exile target creature or planeswalker. You gain life equal to the number of counters on it.

Warlock Class

(Gain the next level as a sorcery to add its ability.)
At the beginning of your end step, if a creature died this turn, each opponent loses 1 life.
{1}{B}: Level 2
When this Class becomes level 2, look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.
{6}{B}: Level 3
At the beginning of your end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Dingus Staff

Whenever a creature dies, Dingus Staff deals 2 damage to that creature's controller.

Pontiff of Blight

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Other creatures you control have extort. (If a creature has multiple instances of extort, each triggers separately.)

Bloodsoaked Altar

{T}, Pay 2 life, Discard a card, Sacrifice a creature: Create a 5/5 black Demon creature token with flying. Activate only as a sorcery.

Demon's Horn

Whenever a player casts a black spell, you may gain 1 life.

Spectral Searchlight

{T}: Choose a player. That player adds one mana of any color they choose.

Mage Hunter

Whenever an opponent casts or copies an instant or sorcery spell, they lose 1 life.

Gonti's Machinations

Whenever you lose life for the first time each turn, you get {E}. (You get an energy counter. Damage causes loss of life.)
Pay {E}{E}, Sacrifice Gonti's Machinations: Each opponent loses 3 life. You gain life equal to the life lost this way.

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Eviscerate

Opaline Unicorn

Disciple of Bolas

When Disciple of Bolas enters the battlefield, sacrifice another creature. You gain X life and draw X cards, where X is that creature's power.

Gnawing Zombie

{1}{B}, Sacrifice a creature: Target player loses 1 life and you gain 1 life.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Hand of Vecna

At the beginning of combat on your turn, equipped creature or a creature you control named Vecna gets +X/+X until end of turn, where X is the number of cards in your hand.
Equip—Pay 1 life for each card in your hand.
Equip {2}

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Destroy target creature.

Finishing Blow

Zombie Infestation

Discard two cards: Create a 2/2 black Zombie creature token.

Asmodeus the Archfiend

Binding Contract — If you would draw a card, exile the top card of your library face down instead.
{B}{B}{B}: Draw seven cards.
{B}: Return all cards exiled with Asmodeus the Archfiend to their owner's hand and you lose that much life.

Letter of Acceptance

{T}: Add one mana of any color.
{2}, {T}, Sacrifice Letter of Acceptance: Draw a card.

Malakir Blood-Priest

When Malakir Blood-Priest enters the battlefield, each opponent loses X life and you gain X life, where X is the number of creatures in your party. (Your party consists of up to one each of Cleric, Rogue, Warrior, and Wizard.)

Call the Bloodline

{1}, Discard a card: Create a 1/1 black Vampire Knight creature token with lifelink. Activate only once each turn.

Disciple of Griselbrand

{1}, Sacrifice a creature: You gain life equal to the sacrificed creature's toughness.

Eye of Vecna

When Eye of Vecna enters the battlefield, you draw a card and you lose 2 life.
At the beginning of your upkeep, you may pay {2}. If you do, you draw a card and you lose 2 life.

Vesper Ghoul

{T}, Pay 1 life: Add one mana of any color.

Fountain of Ichor

{T}: Add one mana of any color.
{3}: Fountain of Ichor becomes a 3/3 Dinosaur artifact creature until end of turn.

Zulaport Cutthroat

Whenever Zulaport Cutthroat or another creature you control dies, each opponent loses 1 life and you gain 1 life.

Scuttlemutt

{T}: Add one mana of any color.
{T}: Target creature becomes the color or colors of your choice until end of turn.

Bubbling Cauldron

{1}, {T}, Sacrifice a creature: You gain 4 life.
{1}, {T}, Sacrifice a creature named Festering Newt: Each opponent loses 4 life. You gain life equal to the life lost this way.

Vermin Gorger

{T}, Sacrifice another creature: Each opponent loses 2 life and you gain 2 life.

Lampad of Death's Vigil

{1}, Sacrifice a creature: Each opponent loses 1 life and you gain 1 life.

Profane Transfusion

Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.

Hecatomb

When Hecatomb enters the battlefield, sacrifice Hecatomb unless you sacrifice four creatures.
Tap an untapped Swamp you control: Hecatomb deals 1 damage to any target.