Grow Extra Arms

This spell costs {1} less to cast if it targets a Spider.
Target creature gets +4/+4 until end of turn.

Kraven's Cats

{2}{G}: This creature gets +2/+2 until end of turn. Activate only once each turn.

Electro, Assaulting Battery

Flying
You don't lose unspent red mana as steps and phases end.
Whenever you cast an instant or sorcery spell, add {R}.
When Electro leaves the battlefield, you may pay {X}. When you do, he deals X damage to target player.

Hobgoblin, Mantled Marauder

Flying, haste
Whenever you discard a card, Hobgoblin gets +2/+0 until end of turn.

Costume Closet

This artifact enters with two +1/+1 counters on it.
{T}: Move a +1/+1 counter from this artifact onto target creature you control. Activate only as a sorcery.
Whenever a modified creature you control leaves the battlefield, put a +1/+1 counter on this artifact. (Equipment, Auras you control, and counters are modifications.)

Ezekiel Sims, Spider-Totem

Reach
At the beginning of combat on your turn, target Spider you control gets +2/+2 until end of turn.

Black Cat, Cunning Thief

When Black Cat enters, look at the top nine cards of target opponent's library, exile two of them face down, then put the rest on the bottom of their library in a random order. You may play the exiled cards for as long as they remain exiled. Mana of any type can be spent to cast spells this way.

Electro's Bolt

Electro's Bolt deals 4 damage to target creature.
Mayhem {1}{R} (You may cast this card from your graveyard for {1}{R} if you discarded it this turn. Timing rules still apply.)

Behold the Sinister Six!

Return up to six target creature cards with different names from your graveyard to the battlefield.

Guy in the Chair

{T}: Add one mana of any color.
Web Support — {2}{G}, {T}: Put a +1/+1 counter on target Spider. Activate only as a sorcery.

Kraven the Hunter

Trample
Whenever a creature an opponent controls with the greatest power among creatures that player controls dies, draw a card and put a +1/+1 counter on Kraven the Hunter.

Kapow!

Put a +1/+1 counter on target creature you control. It fights target creature an opponent controls. (Each deals damage equal to its power to the other.)

Doc Ock's Tentacles

Whenever a creature you control with mana value 5 or greater enters, you may attach this Equipment to it.
Equipped creature gets +4/+4.
Equip {5}

Green Goblin, Revenant

Flying, deathtouch
Whenever Green Goblin attacks, discard a card. Then draw a card for each card you've discarded this turn.

Interdimensional Web Watch

When this artifact enters, exile the top two cards of your library. Until the end of your next turn, you may play those cards.
{T}: Add two mana in any combination of colors. Spend this mana only to cast spells from exile.

Venom, Lethal Protector

Menace, trample, haste
Whenever Venom attacks, you may sacrifice another creature. If you do, draw X cards, then you may put a permanent card with mana value X or less from your hand onto the battlefield, where X is the sacrificed creature's mana value.

Eddie Brock

When Eddie Brock enters, return target creature card with mana value 1 or less from your graveyard to the battlefield.
{3}{B}{R}{G}: Transform Eddie Brock. Activate only as a sorcery.

Eddie Brock // Venom, Lethal Protector

City Pigeon

Flying
When this creature leaves the battlefield, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this token: You gain 3 life.")

Beetle, Legacy Criminal

Flying
{1}{U}, Exile this card from your graveyard: Put a +1/+1 counter on target creature. It gains flying until end of turn. Activate only as a sorcery.

Biorganic Carapace

When this Equipment enters, attach it to target creature you control.
Equipped creature gets +2/+2 and has "Whenever this creature deals combat damage to a player, draw a card for each modified creature you control." (Equipment, Auras you control, and counters are modifications.)
Equip {2}

Kraven, Proud Predator

Vigilance
Top of the Food Chain — Kraven's power is equal to the greatest mana value among permanents you control.

Chameleon, Master of Disguise

You may have Chameleon enter as a copy of a creature you control, except his name is Chameleon, Master of Disguise.
Mayhem {2}{U} (You may cast this card from your graveyard for {2}{U} if you discarded it this turn. Timing rules still apply.)

Hide on the Ceiling

Exile X target artifacts and/or creatures. Return the exiled cards to the battlefield under their owners' control at the beginning of the next end step.

Inner Demons Gangsters

Discard a card: This creature gets +1/+0 and gains menace until end of turn. Activate only as a sorcery. (It can't be blocked except by two or more creatures.)

Angry Rabble

Trample
Whenever you cast a spell with mana value 4 or greater, this creature deals 1 damage to each opponent.
{5}{R}: Put two +1/+1 counters on this creature. Activate only as a sorcery.

Cheering Crowd

At the beginning of each player's first main phase, that player may put a +1/+1 counter on this creature. If they do, they add {C} for each counter on it.

Daily Bugle Building

{T}: Add {C}.
{1}, {T}: Add one mana of any color.
Smear Campaign — {1}, {T}: Target legendary creature gains menace until end of turn. Activate only as a sorcery.

Amazing Acrobatics

Choose one or both —
• Counter target spell.
• Tap one or two target creatures.

Doc Ock, Sinister Scientist

As long as there are eight or more cards in your graveyard, Doc Ock has base power and toughness 8/8.
As long as you control another Villain, Doc Ock has hexproof. (He can't be the target of spells or abilities your opponents control.)

Ghost-Spider

Flying, vigilance, haste
Whenever you play a land from exile or cast a spell from exile, put a +1/+1 counter on Ghost-Spider.
Remove two counters from Ghost-Spider: Exile the top card of your library. You may play that card this turn.

Gwen Stacy

When Gwen Stacy enters, exile the top card of your library. You may play that card for as long as you control this creature.
{2}{U}{R}{W}: Transform Gwen Stacy. Activate only as a sorcery.

Gwen Stacy // Ghost-Spider

Iron Spider, Stark Upgrade

Vigilance
{T}: Put a +1/+1 counter on each artifact creature and/or Vehicle you control.
{2}, Remove two +1/+1 counters from among artifacts you control: Draw a card.

Common Crook

When this creature dies, create a Treasure token. (It's an artifact with "{T}, Sacrifice this token: Add one mana of any color.")

Daily Bugle Reporters

When this creature enters, choose one —
• Puff Piece — Put a +1/+1 counter on each of up to two target creatures.
• Investigative Journalism — Return target creature card with mana value 2 or less from your graveyard to your hand.

Doctor Octopus, Master Planner

Other Villains you control get +2/+2.
Your maximum hand size is eight.
At the beginning of your end step, if you have fewer than eight cards in hand, draw cards equal to the difference.

J. Jonah Jameson

When J. Jonah Jameson enters, suspect up to one target creature. (A suspected creature has menace and can't block.)
Whenever a creature you control with menace attacks, create a Treasure token.

Hot Dog Cart

When this artifact enters, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this token: You gain 3 life.")
{T}: Add one mana of any color.

Flying Octobot

Flying
Whenever another Villain you control enters, put a +1/+1 counter on this creature. This ability triggers only once each turn.

Arachne, Psionic Weaver

Web-slinging {W} (You may cast this spell for {W} if you also return a tapped creature you control to its owner's hand.)
As Arachne enters, look at an opponent's hand, then choose a card type other than creature.
Spells of the chosen type cost {1} more to cast.

Bagel and Schmear

Share — {W}, {T}, Sacrifice this artifact: Put a +1/+1 counter on up to one target creature. Draw a card. Activate only as a sorcery.
Nosh — {2}, {T}, Sacrifice this artifact: You gain 3 life and draw a card.

Gwenom, Remorseless

Deathtouch, lifelink
Whenever Gwenom attacks, until end of turn, you may look at the top card of your library any time and you may play cards from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.

Impostor Syndrome

Whenever a nontoken creature you control deals combat damage to a player, create a token that's a copy of it, except it isn't legendary.

Cosmic Spider-Man

Flying, first strike, trample, lifelink, haste
At the beginning of combat on your turn, other Spiders you control gain flying, first strike, trample, lifelink, and haste until end of turn.

Damage Control Crew

When this creature enters, choose one —
• Repair — Return target card with mana value 4 or greater from your graveyard to your hand.
• Impound — Exile target artifact or enchantment.

Heroes' Hangout

Choose one —
• Date Night — Exile the top two cards of your library. Choose one of them. Until the end of your next turn, you may play that card.
• Patrol Night — One or two target creatures each get +1/+0 and gain first strike until end of turn.

Jackal, Genius Geneticist

Trample
Whenever you cast a creature spell with mana value equal to Jackal's power, copy that spell, except the copy isn't legendary. Then put a +1/+1 counter on Jackal. (The copy becomes a token.)

Hydro-Man, Fluid Felon

Whenever you cast a blue spell, if Hydro-Man is a creature, he gets +1/+1 until end of turn.
At the beginning of your end step, untap Hydro-Man. Until your next turn, he becomes a land and gains "{T}: Add {U}." (He's not a creature during that time.)

Eerie Gravestone

When this artifact enters, draw a card.
{1}{B}, Sacrifice this artifact: Mill four cards. You may put a creature card from among them into your hand. (To mill four cards, put the top four cards of your library into your graveyard.)

Anti-Venom, Horrifying Healer

When Anti-Venom enters, if he was cast, return target creature card from your graveyard to the battlefield.
If damage would be dealt to Anti-Venom, prevent that damage and put that many +1/+1 counters on him.

Agent Venom

Flash
Menace
Whenever another nontoken creature you control dies, you draw a card and lose 1 life.

Alien Symbiosis

Enchant creature
Enchanted creature gets +1/+1, has menace, and is a Symbiote in addition to its other types.
You may cast this card from your graveyard by discarding a card in addition to paying its other costs.

Gallant Citizen

Carnage, Crimson Chaos

Trample
When Carnage enters, return target creature card with mana value 3 or less from your graveyard to the battlefield. It gains "This creature attacks each combat if able" and "When this creature deals combat damage to a player, sacrifice it."
Mayhem {B}{R}

Kraven's Last Hunt

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Mill five cards. When you do, this Saga deals damage equal to the greatest power among creature cards in your graveyard to target creature.
II — Target creature you control gets +2/+2 until end of turn.
III — Return target creature card from your graveyard to your hand.

Araña, Heart of the Spider

Whenever you attack, put a +1/+1 counter on target attacking creature.
Whenever a modified creature you control deals combat damage to a player, exile the top card of your library. You may play that card this turn. (Equipment, Auras you control, and counters are modifications.)

Doc Ock's Henchmen

Flash
Whenever this creature attacks, it connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on this creature.)

Aunt May

Whenever another creature you control enters, you gain 1 life. If it's a Spider, put a +1/+1 counter on it.

Flash Thompson, Spider-Fan

Flash
When Flash Thompson enters, choose one or both —
• Heckle — Tap target creature.
• Hero Worship — Untap target creature.

Friendly Neighborhood

Enchant land
When this Aura enters, create three 1/1 green and white Human Citizen creature tokens.
Enchanted land has "{1}, {T}: Target creature gets +1/+1 until end of turn for each creature you control. Activate only as a sorcery."