Vampiric Rites

{1}{B}, Sacrifice a creature: You gain 1 life and draw a card.

Sweettooth Witch

When this creature enters, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this token: You gain 3 life.")
{2}, Sacrifice a Food: Target player loses 2 life.

Unstoppable Slasher

Deathtouch
Whenever this creature deals combat damage to a player, they lose half their life, rounded up.
When this creature dies, if it had no counters on it, return it to the battlefield tapped under its owner's control with two stun counters on it.

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Grievous Wound

Enchant player
Enchanted player can't gain life.
Whenever enchanted player is dealt damage, they lose half their life, rounded up.

Lich's Mastery

Hexproof
You can't lose the game.
Whenever you gain life, draw that many cards.
Whenever you lose life, for each 1 life you lost, exile a permanent you control or a card from your hand or graveyard.
When Lich's Mastery leaves the battlefield, you lose the game.

Dread Presence

Whenever a Swamp you control enters, choose one —
• You draw a card and you lose 1 life.
• This creature deals 2 damage to any target and you gain 2 life.

Liliana, Dreadhorde General

Whenever a creature you control dies, draw a card.
+1: Create a 2/2 black Zombie creature token.
−4: Each player sacrifices two creatures of their choice.
−9: Each opponent chooses a permanent they control of each permanent type and sacrifices the rest.

Demogorgon's Clutches

Target opponent discards two cards, mills two cards, and loses 2 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Orcish Bowmasters

Flash
When this creature enters and whenever an opponent draws a card except the first one they draw in each of their draw steps, this creature deals 1 damage to any target. Then amass Orcs 1.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: This artifact deals 50 damage to any target.

Vampire Nighthawk

Flying
Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Arbiter of Woe

As an additional cost to cast this spell, sacrifice a creature.
Flying
When this creature enters, each opponent discards a card and loses 2 life. You draw a card and gain 2 life.

Rise of the Dark Realms

Put all creature cards from all graveyards onto the battlefield under your control.

Swamp

Underworld Dreams

Whenever an opponent draws a card, this enchantment deals 1 damage to that player.

Acolyte of Aclazotz

{T}, Sacrifice another creature or artifact: Each opponent loses 1 life and you gain 1 life.

Overwhelming Forces

Destroy all creatures target opponent controls. Draw a card for each creature destroyed this way.

Blood Artist

Whenever this creature or another creature dies, target player loses 1 life and you gain 1 life.

Sanguine Syphoner

Whenever this creature attacks, each opponent loses 1 life and you gain 1 life.

Winter's Intervention

Winter's Intervention deals 2 damage to target creature. You gain 2 life.

Jet Medallion

Black spells you cast cost {1} less to cast.

Necrodominance

Skip your draw step.
At the beginning of your end step, you may pay any amount of life. If you do, draw that many cards.
Your maximum hand size is five.
If a card or token would be put into your graveyard from anywhere, exile it instead.

Murder

Cabal Stronghold

{T}: Add {C}.
{3}, {T}: Add {B} for each basic Swamp you control.

Shoot the Sheriff

Destroy target non-outlaw creature. (Assassins, Mercenaries, Pirates, Rogues, and Warlocks are outlaws. Everyone else is fair game.)

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Tinybones, the Pickpocket

Deathtouch
Whenever Tinybones deals combat damage to a player, you may cast target nonland permanent card from that player's graveyard, and mana of any type can be spent to cast that spell.

Vengeful Bloodwitch

Whenever this creature or another creature you control dies, target opponent loses 1 life and you gain 1 life.

Savage Gorger

Flying
At the beginning of your end step, if an opponent lost life this turn, put a +1/+1 counter on this creature. (Damage causes loss of life.)

Dark Ritual

Fountain of Renewal

At the beginning of your upkeep, you gain 1 life.
{3}, Sacrifice this artifact: Draw a card.

Let's Play a Game

Delirium — Choose one. If there are four or more card types among cards in your graveyard, choose one or more instead.
• Creatures your opponents control get -1/-1 until end of turn.
• Each opponent discards two cards.
• Each opponent loses 3 life and you gain 3 life.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Nightmare

Flying (This creature can't be blocked except by creatures with flying or reach.)
Nightmare's power and toughness are each equal to the number of Swamps you control.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Dark Nourishment

Dark Nourishment deals 3 damage to any target. You gain 3 life.

Black Market

Whenever a creature dies, put a charge counter on this enchantment.
At the beginning of your first main phase, add {B} for each charge counter on this enchantment.

Polluted Bonds

Whenever a land an opponent controls enters, that player loses 2 life and you gain 2 life.

Ob Nixilis, the Hate-Twisted

Whenever an opponent draws a card, Ob Nixilis deals 1 damage to that player.
−2: Destroy target creature. Its controller draws two cards.

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Starscape Cleric

Offspring {2}{B} (You may pay an additional {2}{B} as you cast this spell. If you do, when this creature enters, create a 1/1 token copy of it.)
Flying
This creature can't block.
Whenever you gain life, each opponent loses 1 life.

Skeleton Archer

When this creature enters, it deals 1 damage to any target.

Scrawling Crawler

At the beginning of your upkeep, each player draws a card.
Whenever an opponent draws a card, that player loses 1 life.

Epicure of Blood

Moment of Craving

Target creature gets -2/-2 until end of turn. You gain 2 life.

Mind's Eye

Whenever an opponent draws a card, you may pay {1}. If you do, draw a card.

Blood Pact

Target player draws two cards and loses 2 life.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Collective Brutality

Escalate—Discard a card. (Pay this cost for each mode chosen beyond the first.)
Choose one or more —
• Target opponent reveals their hand. You choose an instant or sorcery card from it. That player discards that card.
• Target creature gets -2/-2 until end of turn.
• Target opponent loses 2 life and you gain 2 life.