Pristine Talisman

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Black Market Connections

At the beginning of your precombat main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It has every creature type.)

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Amalia Benavides Aguirre

Ward—Pay 3 life.
Whenever you gain life, Amalia Benavides Aguirre explores. Then destroy all other creatures if its power is exactly 20. (To have this creature explore, reveal the top card of your library. Put that card into your hand if it's a land. Otherwise, put a +1/+1 counter on this creature, then put the card back or put it into your graveyard.)

Celestine, the Living Saint

Flying, lifelink
Healing Tears — At the beginning of your end step, return target creature card with mana value X or less from your graveyard to the battlefield, where X is the amount of life you gained this turn.

Elenda's Hierophant

Flying
Whenever you gain life, put a +1/+1 counter on Elenda's Hierophant.
When Elenda's Hierophant dies, create X 1/1 white Vampire creature tokens with lifelink, where X is its power.

Serra Avatar

Serra Avatar's power and toughness are each equal to your life total.
When Serra Avatar is put into a graveyard from anywhere, shuffle it into its owner's library.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter the battlefield tapped.

Cyclonic Rift

Return target nonland permanent you don't control to its owner's hand.
Overload {6}{U} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Arcane Sanctum

Arcane Sanctum enters the battlefield tapped.
{T}: Add {W}, {U}, or {B}.

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.

Dimir Signet

Felidar Sovereign

Vigilance, lifelink
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Vault of Champions

Vault of Champions enters the battlefield tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Soul Warden

Whenever another creature enters the battlefield, you gain 1 life.

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, Serra Ascendant gets +5/+5 and has flying.

Propaganda

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Ghostly Prison

Hallowed Fountain

({T}: Add {W} or {U}.)
As Hallowed Fountain enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Esper Sentinel

Whenever an opponent casts their first noncreature spell each turn, draw a card unless that player pays {X}, where X is Esper Sentinel's power.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Drogskol Reaver

Flying, double strike, lifelink
Whenever you gain life, draw a card.

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Boon Reflection

If you would gain life, you gain twice that much life instead.

Heliod, Sun-Crowned

Indestructible
As long as your devotion to white is less than five, Heliod isn't a creature.
Whenever you gain life, put a +1/+1 counter on target creature or enchantment you control.
{1}{W}: Another target creature gains lifelink until end of turn.

Sea of Clouds

Sea of Clouds enters the battlefield tapped unless you have two or more opponents.
{T}: Add {W} or {U}.

Karlov of the Ghost Council

Whenever you gain life, put two +1/+1 counters on Karlov of the Ghost Council.
{W}{B}, Remove six +1/+1 counters from Karlov of the Ghost Council: Exile target creature.

Morphic Pool

Morphic Pool enters the battlefield tapped unless you have two or more opponents.
{T}: Add {U} or {B}.

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Crawlspace

No more than two creatures can attack you each combat.

Queza, Augur of Agonies

Whenever you draw a card, target opponent loses 1 life and you gain 1 life.

Soul's Attendant

Whenever another creature enters the battlefield, you may gain 1 life.

Command Tower

Orzhov Signet

Talisman of Progress

{T}: Add {C}.
{T}: Add {W} or {U}. Talisman of Progress deals 1 damage to you.

Oloro, Ageless Ascetic

At the beginning of your upkeep, you gain 2 life.
Whenever you gain life, you may pay {1}. If you do, draw a card and each opponent loses 1 life.
At the beginning of your upkeep, if Oloro, Ageless Ascetic is in the command zone, you gain 2 life.

The Gaffer

At the beginning of each end step, if you gained 3 or more life this turn, draw a card.

Will, Scion of Peace

Vigilance
{T}: Spells you cast this turn that are white and/or blue cost {X} less to cast, where X is the amount of life you gained this turn. Activate only as a sorcery.

Sol Ring

Azorius Signet

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Voice of the Blessed

Whenever you gain life, put a +1/+1 counter on Voice of the Blessed.
As long as Voice of the Blessed has four or more +1/+1 counters on it, it has flying and vigilance.
As long as Voice of the Blessed has ten or more +1/+1 counters on it, it has indestructible.

Authority of the Consuls

Creatures your opponents control enter the battlefield tapped.
Whenever a creature enters the battlefield under an opponent's control, you gain 1 life.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Raffine's Tower

({T}: Add {W}, {U}, or {B}.)
Raffine's Tower enters the battlefield tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Lotho, Corrupt Shirriff

Whenever a player casts their second spell each turn, you lose 1 life and create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Watery Grave

({T}: Add {U} or {B}.)
As Watery Grave enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Sensei's Divining Top

{1}: Look at the top three cards of your library, then put them back in any order.
{T}: Draw a card, then put Sensei's Divining Top on top of its owner's library.

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature and you return up to one target creature card from your graveyard to your hand.

Loxodon Warhammer

Equipped creature gets +3/+0 and has trample and lifelink.
Equip {3}

Trouble in Pairs

If an opponent would begin an extra turn, that player skips that turn instead.
Whenever an opponent attacks you with two or more creatures, draws their second card each turn, or casts their second spell each turn, you draw a card.

Crested Sunmare

Other Horses you control have indestructible.
At the beginning of each end step, if you gained life this turn, create a 5/5 white Horse creature token.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Exotic Orchard

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life.