Exocrine

Ravenous (This creature enters the battlefield with X +1/+1 counters on it. If X is 5 or more, draw a card when it enters.)
Bio-plasmic Barrage — When Exocrine enters the battlefield, it deals X damage to each player and each other creature.

Their Number Is Legion

Create X tapped 2/2 black Necron Warrior artifact creature tokens, then you gain life equal to the number of artifacts you control. Exile Their Number Is Legion.
You may cast Their Number Is Legion from your graveyard.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Fake Your Own Death

Until end of turn, target creature gets +2/+0 and gains "When this creature dies, return it to the battlefield tapped under its owner's control and you create a Treasure token." (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Night's Whisper

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Infernal Grasp

Destroy target creature. You lose 2 life.

Moltensteel Dragon

({R/P} can be paid with either {R} or 2 life.)
Flying
{R/P}: Moltensteel Dragon gets +1/+0 until end of turn.

Stonesplitter Bolt

Bargain (You may sacrifice an artifact, enchantment, or token as you cast this spell.)
Stonesplitter Bolt deals X damage to target creature or planeswalker. If this spell was bargained, it deals twice X damage to that permanent instead.

Foreboding Ruins

As Foreboding Ruins enters the battlefield, you may reveal a Swamp or Mountain card from your hand. If you don't, Foreboding Ruins enters the battlefield tapped.
{T}: Add {B} or {R}.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Defiler of Instinct

First strike
As an additional cost to cast red permanent spells, you may pay 2 life. Those spells cost {R} less to cast if you paid life this way. This effect reduces only the amount of red mana you pay.
Whenever you cast a red permanent spell, Defiler of Instinct deals 1 damage to any target.

Fire Covenant

As an additional cost to cast this spell, pay X life.
Fire Covenant deals X damage divided as you choose among any number of target creatures.

Razaketh's Rite

Search your library for a card, put that card into your hand, then shuffle.
Cycling {B} ({B}, Discard this card: Draw a card.)

Call of the Ring

At the beginning of your upkeep, the Ring tempts you.
Whenever you choose a creature as your Ring-bearer, you may pay 2 life. If you do, draw a card.

Ambition's Cost

You draw three cards and you lose 3 life.

Swamp

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Sol Ring

Treasonous Ogre

Dethrone (Whenever this creature attacks the player with the most life or tied for most life, put a +1/+1 counter on it.)
Pay 3 life: Add {R}.

Twinflame

Strive — This spell costs {2}{R} more to cast for each target beyond the first.
Choose any number of target creatures you control. For each of them, create a token that's a copy of that creature, except it has haste. Exile those tokens at the beginning of the next end step.

Blood Pact

Target player draws two cards and loses 2 life.

Damnable Pact

Target player draws X cards and loses X life.

Bojuka Bog

Bojuka Bog enters the battlefield tapped.
When Bojuka Bog enters the battlefield, exile target player's graveyard.
{T}: Add {B}.

Descent into Avernus

At the beginning of your upkeep, put two descent counters on Descent into Avernus. Then each player creates X Treasure tokens and Descent into Avernus deals X damage to each player, where X is the number of descent counters on Descent into Avernus.

Arco-Flagellant

Squad {2} (As an additional cost to cast this spell, you may pay {2} any number of times. When this creature enters the battlefield, create that many tokens that are copies of it.)
Arco-Flagellant can't block.
Endurant — Pay 3 life: Arco-Flagellant gains indestructible until end of turn.

Barbarian Ring

{T}: Add {R}. Barbarian Ring deals 1 damage to you.
Threshold — {R}, {T}, Sacrifice Barbarian Ring: It deals 2 damage to any target. Activate only if seven or more cards are in your graveyard.

Swallowing Plague

Swallowing Plague deals X damage to target creature and you gain X life.

Crackle with Power

Crackle with Power deals five times X damage to each of up to X targets.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Dragonskull Summit

Dragonskull Summit enters the battlefield tapped unless you control a Swamp or a Mountain.
{T}: Add {B} or {R}.

Apex of Power

Exile the top seven cards of your library. Until end of turn, you may cast spells from among them.
If this spell was cast from your hand, add ten mana of any one color.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Rowan's Grim Search

Bargain (You may sacrifice an artifact, enchantment, or token as you cast this spell.)
If this spell was bargained, look at the top four cards of your library, then put up to two of them back on top of your library in any order and the rest into your graveyard.
You draw two cards and you lose 2 life.

Battle at the Bridge

Improvise (Your artifacts can help cast this spell. Each artifact you tap after you're done activating mana abilities pays for {1}.)
Target creature gets -X/-X until end of turn. You gain X life.

Defiler of Flesh

Menace
As an additional cost to cast black permanent spells, you may pay 2 life. Those spells cost {B} less to cast if you paid life this way. This effect reduces only the amount of black mana you pay.
Whenever you cast a black permanent spell, target creature you control gets +1/+1 and gains menace until end of turn.

Vendetta

Destroy target nonblack creature. It can't be regenerated. You lose life equal to that creature's toughness.

City on Fire

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
If a source you control would deal damage to a permanent or player, it deals triple that damage instead.

Profane Transfusion

Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.

Solphim, Mayhem Dominus

If a source you control would deal noncombat damage to an opponent or a permanent an opponent controls, it deals double that damage to that player or permanent instead.
{1}{R/P}{R/P}, Discard two cards: Put an indestructible counter on Solphim, Mayhem Dominus. ({R/P} can be paid with either {R} or 2 life.)

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

Bolt Bend

This spell costs {3} less to cast if you control a creature with power 4 or greater.
Change the target of target spell or ability with a single target.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent or discards a card.

Fervent Mastery

You may pay {2}{R}{R} rather than pay this spell's mana cost.
If the {2}{R}{R} cost was paid, an opponent discards any number of cards, then draws that many cards.
Search your library for up to three cards, put them into your hand, shuffle, then discard three cards at random.

Myr Convert

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
{T}, Pay 2 life: Add one mana of any color.

Ramunap Ruins

{T}: Add {C}.
{T}, Pay 1 life: Add {R}.
{2}{R}{R}, {T}, Sacrifice a Desert: Ramunap Ruins deals 2 damage to each opponent.

Diabolic Revelation

Search your library for up to X cards, put those cards into your hand, then shuffle.

Tainted Peak

{T}: Add {C}.
{T}: Add {B} or {R}. Activate only if you control a Swamp.

Read the Bones

Scry 2, then draw two cards. You lose 2 life.

Jaya's Immolating Inferno

(You may cast a legendary sorcery only if you control a legendary creature or planeswalker.)
Jaya's Immolating Inferno deals X damage to each of up to three targets.

Snuff Out

If you control a Swamp, you may pay 4 life rather than pay this spell's mana cost.
Destroy target nonblack creature. It can't be regenerated.

March of Reckless Joy

As an additional cost to cast this spell, you may exile any number of red cards from your hand. This spell costs {2} less to cast for each card exiled this way.
Exile the top X cards of your library. You may play up to two of those cards until the end of your next turn.

Rakdos Signet

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Not Dead After All

Until end of turn, target creature you control gains "When this creature dies, return it to the battlefield tapped under its owner's control, then create a Wicked Role token attached to it." (Enchanted creature gets +1/+1. When this Aura is put into a graveyard, each opponent loses 1 life.)

Mountain

Tavern Swindler

{T}, Pay 3 life: Flip a coin. If you win the flip, you gain 6 life.

Smoldering Marsh

({T}: Add {B} or {R}.)
Smoldering Marsh enters the battlefield tapped unless you control two or more basic lands.

Stormfist Crusader

Menace
At the beginning of your upkeep, each player draws a card and loses 1 life.

Arcane Signet

Fellwar Stone

Judith, Carnage Connoisseur

Whenever you cast an instant or sorcery spell, choose one —
• That spell gains deathtouch and lifelink.
• Create a 2/2 red Imp creature token with "When this creature dies, it deals 2 damage to each opponent."

Shadowblood Ridge

War Room

{T}: Add {C}.
{3}, {T}, Pay life equal to the number of colors in your commanders' color identity: Draw a card.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Greed

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Storm King's Thunder

When you next cast an instant or sorcery spell this turn, copy that spell X times. You may choose new targets for the copies.

Tibalt's Trickery

Counter target spell. Choose 1, 2, or 3 at random. Its controller mills that many cards, then exiles cards from the top of their library until they exile a nonland card with a different name than that spell. They may cast that card without paying its mana cost. Then they put the exiled cards on the bottom of their library in a random order.

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: Wall of Blood gets +1/+1 until end of turn.

Delete

Delete deals X damage to each nonartifact creature and each player.

Hell to Pay

Hell to Pay deals X damage to target creature. Create a number of tapped Treasure tokens equal to the amount of excess damage dealt to that creature this way.

Talisman of Indulgence

{T}: Add {C}.
{T}: Add {B} or {R}. Talisman of Indulgence deals 1 damage to you.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters the battlefield, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Noxious Gearhulk

Menace
When Noxious Gearhulk enters the battlefield, you may destroy another target creature. If a creature is destroyed this way, you gain life equal to its toughness.

Doom Whisperer

Flying, trample
Pay 2 life: Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Cabal Pit

{T}: Add {B}. Cabal Pit deals 1 damage to you.
Threshold — {B}, {T}, Sacrifice Cabal Pit: Target creature gets -2/-2 until end of turn. Activate only if seven or more cards are in your graveyard.

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Rowan, Scion of War

Menace
{T}: Spells you cast this turn that are black and/or red cost {X} less to cast, where X is the amount of life you lost this turn. Activate only as a sorcery.

Rune-Scarred Demon

Flying
When Rune-Scarred Demon enters the battlefield, search your library for a card, put it into your hand, then shuffle.