Ob Nixilis of the Black Oath

+2: Each opponent loses 1 life. You gain life equal to the life lost this way.
−2: Create a 5/5 black Demon creature token with flying. You lose 2 life.
−8: You get an emblem with "{1}{B}, Sacrifice a creature: You gain X life and draw X cards, where X is the sacrificed creature's power."
Ob Nixilis of the Black Oath can be your commander.

Have

Boon Reflection

If you would gain life, you gain twice that much life instead.

The Shire

The Shire enters the battlefield tapped unless you control a legendary creature.
{T}: Add {G}.
{1}{G}, {T}, Tap an untapped creature you control: Create a Food token.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Kitchen Finks

When Kitchen Finks enters the battlefield, you gain 2 life.
Persist (When this creature dies, if it had no -1/-1 counters on it, return it to the battlefield under its owner's control with a -1/-1 counter on it.)

Gollum, Obsessed Stalker

Skulk (This creature can't be blocked by creatures with greater power.)
At the beginning of your end step, each opponent dealt combat damage this game by a creature named Gollum, Obsessed Stalker loses life equal to the amount of life you gained this turn.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Evolving Wilds

{T}, Sacrifice Evolving Wilds: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Terramorphic Expanse

{T}, Sacrifice Terramorphic Expanse: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Tablet of the Guilds

As Tablet of the Guilds enters the battlefield, choose two colors.
Whenever you cast a spell, if it's at least one of the chosen colors, you gain 1 life for each of the chosen colors it is.

Righteous Cause

Whenever a creature attacks, you gain 1 life.

Knight of Dawn's Light

First strike
If you would gain life, you gain that much life plus 1 instead.
{1}{W}: Knight of Dawn's Light gets +1/+1 until end of turn.

Plains

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Triskelion

Triskelion enters the battlefield with three +1/+1 counters on it.
Remove a +1/+1 counter from Triskelion: It deals 1 damage to any target.

Soul Warden

Whenever another creature enters the battlefield, you gain 1 life.

Frodo, Adventurous Hobbit

Partner with Sam, Loyal Attendant
Vigilance
Whenever Frodo, Adventurous Hobbit attacks, if you gained 3 or more life this turn, the Ring tempts you. Then if Frodo is your Ring-bearer and the Ring has tempted you two or more times this game, draw a card.

Vish Kal, Blood Arbiter

Flying, lifelink
Sacrifice a creature: Put X +1/+1 counters on Vish Kal, Blood Arbiter, where X is the sacrificed creature's power.
Remove all +1/+1 counters from Vish Kal: Target creature gets -1/-1 until end of turn for each +1/+1 counter removed this way.

Bilbo, Birthday Celebrant

If you would gain life, you gain that much life plus 1 instead.
{2}{W}{B}{G}, {T}, Exile Bilbo, Birthday Celebrant: Search your library for any number of creature cards, put them onto the battlefield, then shuffle. Activate only if you have 111 or more life.

Ajani, Mentor of Heroes

+1: Distribute three +1/+1 counters among one, two, or three target creatures you control.
+1: Look at the top four cards of your library. You may reveal an Aura, creature, or planeswalker card from among them and put it into your hand. Put the rest on the bottom of your library in any order.
−8: You gain 100 life.

Essence Warden

Selesnya Sanctuary

Selesnya Sanctuary enters the battlefield tapped.
When Selesnya Sanctuary enters the battlefield, return a land you control to its owner's hand.
{T}: Add {G}{W}.

Agent of Masks

At the beginning of your upkeep, each opponent loses 1 life. You gain life equal to the life lost this way.

Shielded by Faith

Enchant creature
Enchanted creature has indestructible.
Whenever a creature enters the battlefield, you may attach Shielded by Faith to that creature.

Lifegift

Whenever a land enters the battlefield, you may gain 1 life.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Blighted Steppe

{T}: Add {C}.
{3}{W}, {T}, Sacrifice Blighted Steppe: You gain 2 life for each creature you control.

Revenge of Ravens

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life and you gain 1 life.

Resplendent Angel

Flying
At the beginning of each end step, if you gained 5 or more life this turn, create a 4/4 white Angel creature token with flying and vigilance.
{3}{W}{W}{W}: Until end of turn, Resplendent Angel gets +2/+2 and gains lifelink.

Sanctum of the Sun

(Transforms from Azor's Gateway.)
{T}: Add X mana of any one color, where X is your life total.

Azor's Gateway

{1}, {T}: Draw a card, then exile a card from your hand. If cards with five or more different mana values are exiled with Azor's Gateway, you gain 5 life, untap Azor's Gateway, and transform it.

Azor's Gateway // Sanctum of the Sun

Angel of Destiny

Flying, double strike
Whenever a creature you control deals combat damage to a player, you and that player each gain that much life.
At the beginning of your end step, if you have at least 15 life more than your starting life total, each player Angel of Destiny attacked this turn loses the game.

The Gaffer

At the beginning of each end step, if you gained 3 or more life this turn, draw a card.

Treebeard, Gracious Host

Trample, ward {2}
When Treebeard, Gracious Host enters the battlefield, create two Food tokens.
Whenever you gain life, put that many +1/+1 counters on target Halfling or Treefolk.

Mazemind Tome

{T}, Put a page counter on Mazemind Tome: Scry 1.
{2}, {T}, Put a page counter on Mazemind Tome: Draw a card.
When there are four or more page counters on Mazemind Tome, exile it. If you do, you gain 4 life.

Brokers Hideout

When Brokers Hideout enters the battlefield, sacrifice it. When you do, search your library for a basic Forest, Plains, or Island card, put it onto the battlefield tapped, then shuffle and you gain 1 life.

Pippin, Warden of Isengard

Partner with Merry, Warden of Isengard (When this creature enters the battlefield, target player may put Merry into their hand from their library, then shuffle.)
{1}, {T}: Create a Food token.
{T}, Sacrifice four Foods: Other creatures you control get +3/+3 and gain haste until end of turn. Activate only as a sorcery.

Ajani, Wise Counselor

+2: You gain 1 life for each creature you control.
−3: Creatures you control get +2/+2 until end of turn.
−9: Put X +1/+1 counters on target creature, where X is your life total.

Mask of Avacyn

Equipped creature gets +1/+2 and has hexproof. (It can't be the target of spells or abilities your opponents control.)
Equip {3}

Cleric Class

(Gain the next level as a sorcery to add its ability.)
If you would gain life, you gain that much life plus 1 instead.
{3}{W}: Level 2
Whenever you gain life, put a +1/+1 counter on target creature you control.
{4}{W}: Level 3
When this Class becomes level 3, return target creature card from your graveyard to the battlefield. You gain life equal to that creature's toughness.

Restless Fortress

Restless Fortress enters the battlefield tapped.
{T}: Add {W} or {B}.
{2}{W}{B}: Restless Fortress becomes a 1/4 white and black Nightmare creature until end of turn. It's still a land.
Whenever Restless Fortress attacks, defending player loses 2 life and you gain 2 life.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Selesnya Guildgate

Selesnya Guildgate enters the battlefield tapped.
{T}: Add {G} or {W}.

Gilded Goose

Flying
When Gilded Goose enters the battlefield, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")
{1}{G}, {T}: Create a Food token.
{T}, Sacrifice a Food: Add one mana of any color.

Field-Tested Frying Pan

When Field-Tested Frying Pan enters the battlefield, create a Food token, then create a 1/1 white Halfling creature token and attach Field-Tested Frying Pan to it.
Equipped creature has "Whenever you gain life, this creature gets +X/+X until end of turn, where X is the amount of life you gained."
Equip {2}

Isolated Chapel

Isolated Chapel enters the battlefield tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Soul's Attendant

Whenever another creature enters the battlefield, you may gain 1 life.

Sandsteppe Citadel

Sandsteppe Citadel enters the battlefield tapped.
{T}: Add {W}, {B}, or {G}.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Obscura Storefront

When Obscura Storefront enters the battlefield, sacrifice it. When you do, search your library for a basic Plains, Island, or Swamp card, put it onto the battlefield tapped, then shuffle and you gain 1 life.

Mikaeus, the Unhallowed

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
Whenever a Human deals damage to you, destroy it.
Other non-Human creatures you control get +1/+1 and have undying. (When a creature with undying dies, if it had no +1/+1 counters on it, return it to the battlefield under its owner's control with a +1/+1 counter on it.)

Ajani, Valiant Protector

+2: Put two +1/+1 counters on up to one target creature.
+1: Reveal cards from the top of your library until you reveal a creature card. Put that card into your hand and the rest on the bottom of your library in a random order.
−11: Put X +1/+1 counters on target creature, where X is your life total. That creature gains trample until end of turn.

Arcane Encyclopedia

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Canopy Vista

({T}: Add {G} or {W}.)
Canopy Vista enters the battlefield tapped unless you control two or more basic lands.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Orzhov Basilica

Orzhov Basilica enters the battlefield tapped.
When Orzhov Basilica enters the battlefield, return a land you control to its owner's hand.
{T}: Add {W}{B}.

Blossoming Sands

Blossoming Sands enters the battlefield tapped.
When Blossoming Sands enters the battlefield, you gain 1 life.
{T}: Add {G} or {W}.

Pristine Talisman

Honor Troll

Vigilance
If you would gain life, you gain that much life plus 1 instead.
Honor Troll gets +2/+1 as long as you have 25 or more life.

Scoured Barrens

Scoured Barrens enters the battlefield tapped.
When Scoured Barrens enters the battlefield, you gain 1 life.
{T}: Add {W} or {B}.

Sun Droplet

Whenever you're dealt damage, put that many charge counters on Sun Droplet.
At the beginning of each upkeep, you may remove a charge counter from Sun Droplet. If you do, you gain 1 life.

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Jungle Hollow

Jungle Hollow enters the battlefield tapped.
When Jungle Hollow enters the battlefield, you gain 1 life.
{T}: Add {B} or {G}.

Samwise Gamgee

Whenever another nontoken creature enters the battlefield under your control, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")
Sacrifice three Foods: Return target historic card from your graveyard to your hand. (Artifacts, legendaries, and Sagas are historic.)

Sol Ring

Sunscorch Regent

Flying
Whenever an opponent casts a spell, put a +1/+1 counter on Sunscorch Regent and you gain 1 life.

Temple of Silence

Temple of Silence enters the battlefield tapped.
When Temple of Silence enters the battlefield, scry 1.
{T}: Add {W} or {B}.

Celestial Mantle

Enchant creature
Enchanted creature gets +3/+3.
Whenever enchanted creature deals combat damage to a player, double its controller's life total.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Heron of Hope

Flying
If you would gain life, you gain that much life plus 1 instead.
{1}{W}: Heron of Hope gains lifelink until end of turn.

Ghost-Lit Redeemer

{W}, {T}: You gain 2 life.
Channel — {1}{W}, Discard Ghost-Lit Redeemer: You gain 4 life.

Tower of Eons

Sakura-Tribe Elder

Sacrifice Sakura-Tribe Elder: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Orzhov Guildgate

Orzhov Guildgate enters the battlefield tapped.
{T}: Add {W} or {B}.

Elspeth Tirel

+2: You gain 1 life for each creature you control.
−2: Create three 1/1 white Soldier creature tokens.
−5: Destroy all other permanents except for lands and tokens.

Myriad Landscape

Myriad Landscape enters the battlefield tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Recumbent Bliss

Enchant creature
Enchanted creature can't attack or block.
At the beginning of your upkeep, you may gain 1 life.

Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Whispersilk Cloak

Equipped creature can't be blocked and has shroud. (It can't be the target of spells or abilities.)
Equip {2}

Swamp

Golgari Guildgate

Golgari Guildgate enters the battlefield tapped.
{T}: Add {B} or {G}.

Cabaretti Courtyard

When Cabaretti Courtyard enters the battlefield, sacrifice it. When you do, search your library for a basic Mountain, Forest, or Plains card, put it onto the battlefield tapped, then shuffle and you gain 1 life.

Dawn of Hope

Whenever you gain life, you may pay {2}. If you do, draw a card.
{3}{W}: Create a 1/1 white Soldier creature token with lifelink.

Angel of Vitality

Flying
If you would gain life, you gain that much life plus 1 instead.
Angel of Vitality gets +2/+2 as long as you have 25 or more life.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Temple of Plenty

Temple of Plenty enters the battlefield tapped.
When Temple of Plenty enters the battlefield, scry 1.
{T}: Add {G} or {W}.

Gift of Immortality

Enchant creature
When enchanted creature dies, return that card to the battlefield under its owner's control. Return Gift of Immortality to the battlefield attached to that creature at the beginning of the next end step.

Forest

Ajani, Strength of the Pride

+1: You gain life equal to the number of creatures you control plus the number of planeswalkers you control.
−2: Create a 2/2 white Cat Soldier creature token named Ajani's Pridemate with "Whenever you gain life, put a +1/+1 counter on Ajani's Pridemate."
0: If you have at least 15 life more than your starting life total, exile Ajani, Strength of the Pride and each artifact and creature your opponents control.