Invoke Despair

Target opponent sacrifices a creature. If they can't, they lose 2 life and you draw a card. Then repeat this process for an enchantment and a planeswalker.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Ornithopter

Gix's Command

Choose two —
• Put two +1/+1 counters on up to one creature. It gains lifelink until end of turn.
• Destroy each creature with power 2 or less.
• Return up to two creature cards from your graveyard to your hand.
• Each opponent sacrifices a creature with the highest power among creatures they control.

Night Clubber

When Night Clubber enters the battlefield, creatures your opponents control get -1/-1 until end of turn.
Blitz {2}{B} (If you cast this spell for its blitz cost, it gains haste and "When this creature dies, draw a card." Sacrifice it at the beginning of the next end step.)

Mask of Griselbrand

Equipped creature has flying and lifelink.
Whenever equipped creature dies, you may pay X life, where X is its power. If you do, draw X cards.
Equip {3}

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Howling Mine

At the beginning of each player's draw step, if Howling Mine is untapped, that player draws an additional card.

Cast Down

Blight-Breath Catoblepas

When Blight-Breath Catoblepas enters the battlefield, target creature an opponent controls gets -X/-X until end of turn, where X is your devotion to black. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Diabolic Intent

As an additional cost to cast this spell, sacrifice a creature.
Search your library for a card, put that card into your hand, then shuffle.

Cut of the Profits

Casualty 3 (As you cast this spell, you may sacrifice a creature with power 3 or greater. When you do, copy this spell.)
You draw X cards and you lose X life.

Collective Nightmare

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Target creature gets -3/-3 until end of turn.

Bladebrand

Target creature gains deathtouch until end of turn.
Draw a card.

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Gruesome Realization

Choose one —
• You draw two cards and you lose 2 life.
• Creatures your opponents control get -1/-1 until end of turn.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Don't Have

Bone Saw

Equipped creature gets +1/+0.
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Mind's Eye

Whenever an opponent draws a card, you may pay {1}. If you do, draw a card.

Go for the Throat

Sol Ring

Master of the Feast

Flying
At the beginning of your upkeep, each opponent draws a card.

Dreams of Steel and Oil

Target opponent reveals their hand. You choose an artifact or creature card from it, then choose an artifact or creature card from their graveyard. Exile the chosen cards.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Yargle, Glutton of Urborg

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Seizan, Perverter of Truth

At the beginning of each player's upkeep, that player loses 2 life and draws two cards.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

The True Scriptures

(As this Saga enters and after your draw step, add a lore counter.)
I — For each opponent, destroy up to one target creature or planeswalker that player controls.
II — Each opponent discards three cards, then mills three cards.
III — Put all creature cards from all graveyards onto the battlefield under your control. Exile The True Scriptures, then return it to the battlefield (front face up).

Sheoldred

Menace
When Sheoldred enters the battlefield, each opponent sacrifices a nontoken creature or planeswalker.
{4}{B}: Exile Sheoldred, then return it to the battlefield transformed under its owner's control. Activate only as a sorcery and only if an opponent has eight or more cards in their graveyard.

Sheoldred // The True Scriptures

Breach the Multiverse

Each player mills ten cards. For each player, choose a creature or planeswalker card in that player's graveyard. Put those cards onto the battlefield under your control. Then each creature you control becomes a Phyrexian in addition to its other types.

Deal Gone Bad

Target creature gets -3/-3 until end of turn. Target player mills three cards. (They put the top three cards of their library into their graveyard.)

Burnished Hart

{3}, Sacrifice Burnished Hart: Search your library for up to two basic land cards, put them onto the battlefield tapped, then shuffle.

Dark Ritual

Rush of Dread

Spree (Choose one or more additional costs.)
+ {1} — Target opponent sacrifices half the creatures they control, rounded up.
+ {2} — Target opponent discards half the cards in their hand, rounded up.
+ {2} — Target opponent loses half their life, rounded up.

Phyrexian Etchings

Cumulative upkeep {B} (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
At the beginning of your end step, draw a card for each age counter on Phyrexian Etchings.
When Phyrexian Etchings is put into a graveyard from the battlefield, you lose 2 life for each age counter on it.

Final Flourish

Kicker—Sacrifice an artifact or creature. (You may sacrifice an artifact or creature in addition to any other costs as you cast this spell.)
Target creature gets -2/-2 until end of turn. If this spell was kicked, that creature gets -6/-6 until end of turn instead.

Grisly Transformation

Enchant creature
When Grisly Transformation enters the battlefield, draw a card.
Enchanted creature has intimidate. (It can't be blocked except by artifact creatures and/or creatures that share a color with it.)

Powerstone Fracture

As an additional cost to cast this spell, sacrifice an artifact or creature.
Destroy target creature or planeswalker.

Stab Wound

Enchant creature
Enchanted creature gets -2/-2.
At the beginning of the upkeep of enchanted creature's controller, that player loses 2 life.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Damnable Pact

Target player draws X cards and loses X life.

Temple Bell

Scorn-Blade Berserker

Backup 1 (When this creature enters the battlefield, put a +1/+1 counter on target creature. If that's another creature, it gains the following ability until end of turn.)
{1}, Sacrifice this creature: Draw a card.

Gurmag Swiftwing

Swamp

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Nothic

Weird Insight — When Nothic dies, roll a d20.
1—9 | You draw a card and you lose 1 life.
10—19 | You draw two cards and you lose 2 life.
20 | You draw seven cards and you lose 7 life.

Trench Stalker

As long as you've drawn two or more cards this turn, Trench Stalker has deathtouch and lifelink.

Overwhelming Remorse

This spell costs {1} less to cast for each creature card in your graveyard.
Exile target creature or planeswalker.

Offer Immortality

Target creature gains deathtouch and indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Moment of Defiance

Target creature gets +2/+1 and gains lifelink until end of turn.
Draw a card.

Teferi's Puzzle Box

At the beginning of each player's draw step, that player puts the cards in their hand on the bottom of their library in any order, then draws that many cards.

Sign in Blood

Target player draws two cards and loses 2 life.

The Toymaker's Trap

At the beginning of your upkeep, secretly choose a number between 1 and 5 that hasn't been chosen. If you do, an opponent guesses which number you chose, then you reveal the number you chose. If they guessed wrong, they lose life equal to the number they guessed and you draw a card. If they guessed right, sacrifice The Toymaker's Trap.

Staff of Domination

{1}: Untap Staff of Domination.
{2}, {T}: You gain 1 life.
{3}, {T}: Untap target creature.
{4}, {T}: Tap target creature.
{5}, {T}: Draw a card.

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Ivory Tower

At the beginning of your upkeep, you gain X life, where X is the number of cards in your hand minus 4.

Clawing Torment

Enchant artifact or creature
As long as enchanted permanent is a creature, it gets -1/-1 and can't block.
Enchanted permanent has "At the beginning of your upkeep, you lose 1 life."

Thraxodemon

{3}, {T}, Sacrifice another creature or artifact: Draw a card.

Murder

Inherited Fiend

Flying
{2}{B}: Exile target creature card from a graveyard. Put a +1/+1 counter on Inherited Fiend.

Heirloom Mirror

{1}, {T}, Pay 1 life, Discard a card: Draw a card, mill a card, then put a ritual counter on Heirloom Mirror. Then if it has three or more ritual counters on it, remove them and transform it. Activate only as a sorcery.

Heirloom Mirror // Inherited Fiend

Scrapwork Rager

When Scrapwork Rager enters the battlefield, you draw a card and you lose 1 life.
Unearth {3}{B} ({3}{B}: Return this card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step or if it would leave the battlefield. Unearth only as a sorcery.)

Demon of Death's Gate

You may pay 6 life and sacrifice three black creatures rather than pay this spell's mana cost.
Flying, trample

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Journeyer's Kite

{3}, {T}: Search your library for a basic land card, reveal it, put it into your hand, then shuffle.