Have

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Fetid Heath

{T}: Add {C}.
{W/B}, {T}: Add {W}{W}, {W}{B}, or {B}{B}.

Charismatic Conqueror

Vigilance
Whenever an artifact or creature enters the battlefield untapped and under an opponent's control, they may tap that permanent. If they don't, you create a 1/1 white Vampire creature token with lifelink.

Swamp

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, Serra Ascendant gets +5/+5 and has flying.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Study Hall

{T}: Add {C}.
{1}, {T}: Add one mana of any color. When you spend this mana to cast your commander, scry X, where X is the number of times it's been cast from the command zone this game.

Damn

Destroy target creature. A creature destroyed this way can't be regenerated.
Overload {2}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Bojuka Bog

Bojuka Bog enters the battlefield tapped.
When Bojuka Bog enters the battlefield, exile target player's graveyard.
{T}: Add {B}.

Isolated Chapel

Isolated Chapel enters the battlefield tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Shadowy Backstreet

({T}: Add {W} or {B}.)
Shadowy Backstreet enters the battlefield tapped.
When Shadowy Backstreet enters the battlefield, surveil 1. (Look at the top card of your library. You may put it into your graveyard.)

Pelakka Caverns

Pelakka Caverns enters the battlefield tapped.
{T}: Add {B}.

Pelakka Predation

Target opponent reveals their hand. You choose a card from it with mana value 3 or greater. That player discards that card.

Pelakka Predation // Pelakka Caverns

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Black Market Connections

At the beginning of your precombat main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It has every creature type.)

Twilight Prophet

Flying
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your upkeep, if you have the city's blessing, reveal the top card of your library and put it into your hand. Each opponent loses X life and you gain X life, where X is that card's mana value.

Temple of Silence

Temple of Silence enters the battlefield tapped.
When Temple of Silence enters the battlefield, scry 1.
{T}: Add {W} or {B}.

Shineshadow Snarl

As Shineshadow Snarl enters the battlefield, you may reveal a Plains or Swamp card from your hand. If you don't, Shineshadow Snarl enters the battlefield tapped.
{T}: Add {W} or {B}.

Preacher of the Schism

Deathtouch
Whenever Preacher of the Schism attacks the player with the most life or tied for most life, create a 1/1 white Vampire creature token with lifelink.
Whenever Preacher of the Schism attacks while you have the most life or are tied for most life, you draw a card and you lose 1 life.

Soul Warden

Whenever another creature enters the battlefield, you gain 1 life.

Silent Clearing

{T}, Pay 1 life: Add {W} or {B}.
{1}, {T}, Sacrifice Silent Clearing: Draw a card.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. Caves of Koilos deals 1 damage to you.

Divinity of Pride

Flying, lifelink
Divinity of Pride gets +4/+4 as long as you have 25 or more life.

Erebos, God of the Dead

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Your opponents can't gain life.
{1}{B}, Pay 2 life: Draw a card.

Forbidden Orchard

{T}: Add one mana of any color.
Whenever you tap Forbidden Orchard for mana, target opponent creates a 1/1 colorless Spirit creature token.

Farewell

Choose one or more —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all graveyards.

Tablet of the Guilds

As Tablet of the Guilds enters the battlefield, choose two colors.
Whenever you cast a spell, if it's at least one of the chosen colors, you gain 1 life for each of the chosen colors it is.

Firemane Commando

Flying
Whenever you attack with two or more creatures, draw a card.
Whenever another player attacks with two or more creatures, they draw a card if none of those creatures attacked you.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Breena, the Demagogue

Flying
Whenever a player attacks one of your opponents, if that opponent has more life than another of your opponents, that attacking player draws a card and you put two +1/+1 counters on a creature you control.

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Cryptic Caves

{T}: Add {C}.
{1}, {T}, Sacrifice Cryptic Caves: Draw a card. Activate only if you control five or more lands.

Heliod's Intervention

Choose one —
• Destroy X target artifacts and/or enchantments.
• Target player gains twice X life.

Fracture

Destroy target artifact, enchantment, or planeswalker.

The Meathook Massacre

When The Meathook Massacre enters the battlefield, each creature gets -X/-X until end of turn.
Whenever a creature you control dies, each opponent loses 1 life.
Whenever a creature an opponent controls dies, you gain 1 life.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Plains

Sunlit Marsh

({T}: Add {W} or {B}.)
Sunlit Marsh enters the battlefield tapped.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Malakir Mire

Malakir Mire enters the battlefield tapped.
{T}: Add {B}.

Malakir Rebirth

Choose target creature. You lose 2 life. Until end of turn, that creature gains "When this creature dies, return it to the battlefield tapped under its owner's control."

Malakir Rebirth // Malakir Mire

Kabira Crossroads

Kabira Crossroads enters the battlefield tapped.
When Kabira Crossroads enters the battlefield, you gain 2 life.
{T}: Add {W}.

Generous Gift

Destroy target permanent. Its controller creates a 3/3 green Elephant creature token.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters the battlefield, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Tithe Drinker

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)

Imp's Mischief

Change the target of target spell with a single target. You lose life equal to that spell's mana value.

Sunscorch Regent

Flying
Whenever an opponent casts a spell, put a +1/+1 counter on Sunscorch Regent and you gain 1 life.

Lotho, Corrupt Shirriff

Whenever a player casts their second spell each turn, you lose 1 life and create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Tomik, Wielder of Law

Affinity for planeswalkers (This spell costs {1} less to cast for each planeswalker you control.)
Flying, vigilance
Whenever an opponent attacks with creatures, if two or more of those creatures are attacking you and/or planeswalkers you control, that opponent loses 3 life and you draw a card.

Concealed Courtyard

Concealed Courtyard enters the battlefield tapped unless you control two or fewer other lands.
{T}: Add {W} or {B}.

Elenda's Hierophant

Flying
Whenever you gain life, put a +1/+1 counter on Elenda's Hierophant.
When Elenda's Hierophant dies, create X 1/1 white Vampire creature tokens with lifelink, where X is its power.

Read the Bones

Scry 2, then draw two cards. You lose 2 life.

Sejiri Glacier

Sejiri Glacier enters the battlefield tapped.
{T}: Add {W}.

Sejiri Shelter

Target creature you control gains protection from the color of your choice until end of turn.

Sejiri Shelter // Sejiri Glacier

Idyllic Tutor

Search your library for an enchantment card, reveal it, put it into your hand, then shuffle.

Soot Imp

Flying
Whenever a player casts a nonblack spell, that player loses 1 life.

Battle Angels of Tyr

Flying, myriad
Whenever Battle Angels of Tyr deals combat damage to a player, draw a card if that player has more cards in hand than each other player. Then you create a Treasure token if that player controls more lands than each other player. Then you gain 3 life if that player has more life than each other player.

The Argent Etchings

(As this Saga enters and after your draw step, add a lore counter.)
I — Incubate 2 five times, then transform all Incubator tokens you control.
II — Creatures you control get +1/+1 and gain double strike until end of turn.
III — Destroy all other permanents except for artifacts, lands, and Phyrexians. Exile The Argent Etchings, then return it to the battlefield (front face up).

Elesh Norn

Vigilance
Whenever a source an opponent controls deals damage to you or a permanent you control, that source's controller loses 2 life unless they pay {1}.
{2}{W}, Sacrifice three other creatures: Exile Elesh Norn, then return it to the battlefield transformed under its owner's control. Activate only as a sorcery.

Elesh Norn // The Argent Etchings

Nightshade Harvester

Whenever a land enters the battlefield under an opponent's control, that player loses 1 life. Put a +1/+1 counter on Nightshade Harvester.

Snowfield Sinkhole

({T}: Add {W} or {B}.)
Snowfield Sinkhole enters the battlefield tapped.

Orzhov Basilica

Orzhov Basilica enters the battlefield tapped.
When Orzhov Basilica enters the battlefield, return a land you control to its owner's hand.
{T}: Add {W}{B}.

Authority of the Consuls

Creatures your opponents control enter the battlefield tapped.
Whenever a creature enters the battlefield under an opponent's control, you gain 1 life.

Gix, Yawgmoth Praetor

Whenever a creature deals combat damage to one of your opponents, its controller may pay 1 life. If they do, they draw a card.
{4}{B}{B}{B}, Discard X cards: Exile the top X cards of target opponent's library. You may play lands and cast spells from among cards exiled this way without paying their mana costs.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Ash Barrens

{T}: Add {C}.
Basic landcycling {1} ({1}, Discard this card: Search your library for a basic land card, reveal it, put it into your hand, then shuffle.)

Skyclave Basilica

Skyclave Basilica enters the battlefield tapped.
{T}: Add {W}.

Skyclave Cleric

When Skyclave Cleric enters the battlefield, you gain 2 life.

Skyclave Cleric // Skyclave Basilica

Rug of Smothering

Flying
Whenever a player casts a spell, they lose 1 life for each spell they've cast this turn.

Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Lotus Petal

{T}, Sacrifice Lotus Petal: Add one mana of any color.

Auriok Champion

Protection from black and from red
Whenever another creature enters the battlefield, you may gain 1 life.

Shambling Vent

Shambling Vent enters the battlefield tapped.
{T}: Add {W} or {B}.
{1}{W}{B}: Shambling Vent becomes a 2/3 white and black Elemental creature with lifelink until end of turn. It's still a land.

Keen Duelist

At the beginning of your upkeep, you and target opponent each reveal the top card of your library. You each lose life equal to the mana value of the card revealed by the other player. You each put the card you revealed into your hand.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Liesa, Shroud of Dusk

Rather than pay {2} for each previous time you've cast this spell from the command zone this game, pay 2 life that many times.
Flying, lifelink
Whenever a player casts a spell, they lose 2 life.

Great Unclean One

Reverberating Summons — At the beginning of your end step, each opponent loses 2 life. Then for each opponent who has less life than you, create a 1/3 black Demon creature token named Plaguebearer of Nurgle.

Opal Palace

{T}: Add {C}.
{1}, {T}: Add one mana of any color in your commander's color identity. If you spend this mana to cast your commander, it enters the battlefield with a number of additional +1/+1 counters on it equal to the number of times it's been cast from the command zone this game.

Amalia Benavides Aguirre

Ward—Pay 3 life.
Whenever you gain life, Amalia Benavides Aguirre explores. Then destroy all other creatures if its power is exactly 20. (To have this creature explore, reveal the top card of your library. Put that card into your hand if it's a land. Otherwise, put a +1/+1 counter on this creature, then put the card back or put it into your graveyard.)

Mangara, the Diplomat

Lifelink
Whenever an opponent attacks with creatures, if two or more of those creatures are attacking you and/or planeswalkers you control, draw a card.
Whenever an opponent casts their second spell each turn, draw a card.

Despark

Exile target permanent with mana value 4 or greater.

Bloodgift Demon

Flying
At the beginning of your upkeep, target player draws a card and loses 1 life.

Secret Rendezvous

You and target opponent each draw three cards.

Forge of Heroes

{T}: Add {C}.
{T}: Choose target commander that entered the battlefield this turn. Put a +1/+1 counter on it if it's a creature and a loyalty counter on it if it's a planeswalker.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Ankh of Mishra

Whenever a land enters the battlefield, Ankh of Mishra deals 2 damage to that land's controller.

Scoured Barrens

Scoured Barrens enters the battlefield tapped.
When Scoured Barrens enters the battlefield, you gain 1 life.
{T}: Add {W} or {B}.

Radiant Fountain

When Radiant Fountain enters the battlefield, you gain 2 life.
{T}: Add {C}.

Enlightened Tutor

Search your library for an artifact or enchantment card, reveal it, then shuffle and put that card on top.

Cleansing Nova

Choose one —
• Destroy all creatures.
• Destroy all artifacts and enchantments.

Path of Ancestry

Path of Ancestry enters the battlefield tapped.
{T}: Add one mana of any color in your commander's color identity. When that mana is spent to cast a creature spell that shares a creature type with your commander, scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Bellowing Mauler

At the beginning of your end step, each player loses 4 life unless they sacrifice a nontoken creature.

Getting

Caustic Bronco

Whenever Caustic Bronco attacks, reveal the top card of your library and put it into your hand. You lose life equal to that card's mana value if Caustic Bronco isn't saddled. Otherwise, each opponent loses that much life.
Saddle 3 (Tap any number of other creatures you control with total power 3 or more: This Mount becomes saddled until end of turn. Saddle only as a sorcery.)