Blighted Agent

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Blighted Agent can't be blocked.

Vivisurgeon's Insight

Draw three cards. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Flux Channeler

Whenever you cast a noncreature spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Contentious Plan

Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)
Draw a card.

Vat Emergence

Put target creature card from a graveyard onto the battlefield under your control. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Serum Snare

Return target nonland permanent to its owner's hand. If that permanent had mana value 3 or less, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Grim Affliction

Put a -1/-1 counter on target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Gale, Waterdeep Prodigy

Whenever you cast an instant or sorcery spell from your hand, you may cast up to one target card of the other type from your graveyard. If a spell cast from your graveyard this way would be put into your graveyard, exile it instead.
Choose a Background (You can have a Background as a second commander.)

Scion of Halaster

Commander creatures you own have "The first time you would draw a card each turn, instead look at the top two cards of your library. Put one of them into your graveyard and the other back on top of your library. Then draw a card."

Drown in Ichor

Target creature gets -4/-4 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Whisper of the Dross

Target creature gets -1/-1 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Steady Progress

Tezzeret's Gambit

({U/P} can be paid with either {U} or 2 life.)
Draw two cards, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Tekuthal, Inquiry Dominus

Flying
If you would proliferate, proliferate twice instead.
{1}{U/P}{U/P}, Remove three counters from among other artifacts, creatures, and planeswalkers you control: Put an indestructible counter on Tekuthal, Inquiry Dominus. ({U/P} can be paid with either {U} or 2 life.)

Midnight Clock

{T}: Add {U}.
{2}{U}: Put an hour counter on Midnight Clock.
At the beginning of each upkeep, put an hour counter on Midnight Clock.
When the twelfth hour counter is put on Midnight Clock, shuffle your hand and graveyard into your library, then draw seven cards. Exile Midnight Clock.

Radstorm

Storm (When you cast this spell, copy it for each spell cast before it this turn.)
Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Ripples of Potential

Proliferate, then choose any number of permanents you control that had a counter put on them this way. Those permanents phase out. (To proliferate, choose any number of permanents and/or players, then give each another counter of each kind already there. Treat phased-out permanents and anything attached to them as though they don't exist until their controller's next turn.)

Voidwing Hybrid

Flying
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When you proliferate, return Voidwing Hybrid from your graveyard to your hand.

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Pentad Prism

Sunburst (This enters the battlefield with a charge counter on it for each color of mana spent to cast it.)
Remove a charge counter from Pentad Prism: Add one mana of any color.

Spread the Sickness

Destroy target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Dreamtide Whale

Vanishing 2 (This creature enters the battlefield with two time counters on it. At the beginning of your upkeep, remove a time counter from it. When the last is removed, sacrifice it.)
Whenever a player casts their second spell each turn, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Astral Cornucopia

Astral Cornucopia enters the battlefield with X charge counters on it.
{T}: Choose a color. Add one mana of that color for each charge counter on Astral Cornucopia.

Blightbelly Rat

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When Blightbelly Rat dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Guildpact Informant

Flying
Whenever Guildpact Informant deals combat damage to a player or planeswalker, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Thrummingbird

Flying
Whenever Thrummingbird deals combat damage to a player, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Glistening Sphere

Glistening Sphere enters the battlefield tapped.
When Glistening Sphere enters the battlefield, proliferate.
{T}: Add one mana of any color.
Corrupted — {T}: Add three mana of any one color. Activate only if an opponent has three or more poison counters.

Everflowing Chalice

Multikicker {2} (You may pay an additional {2} any number of times as you cast this spell.)
Everflowing Chalice enters the battlefield with a charge counter on it for each time it was kicked.
{T}: Add {C} for each charge counter on Everflowing Chalice.

Crystalline Crawler

Converge — Crystalline Crawler enters the battlefield with a +1/+1 counter on it for each color of mana spent to cast it.
Remove a +1/+1 counter from Crystalline Crawler: Add one mana of any color.
{T}: Put a +1/+1 counter on Crystalline Crawler.

Viral Drake

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{3}{U}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Distorted Curiosity

Corrupted — This spell costs {2} less to cast if an opponent has three or more poison counters.
Draw two cards.

Nardole, Resourceful Cyborg

{T}: Add {U} for each counter on Nardole. Spend this mana only to cast noncreature spells.
Undying (When this creature dies, if it had no +1/+1 counters on it, return it to the battlefield under its owner's control with a +1/+1 counter on it.)
Doctor's companion (You can have two commanders if the other is the Doctor.)

Prologue to Phyresis

Each opponent gets a poison counter.
Draw a card.

Frantic Search

Draw two cards, then discard two cards. Untap up to three lands.

Vraska's Fall

Each opponent sacrifices a creature or planeswalker and gets a poison counter.

Myr Convert

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
{T}, Pay 2 life: Add one mana of any color.

Phyresis Outbreak

Each opponent gets a poison counter. Then each creature your opponents control gets -1/-1 until end of turn for each poison counter its controller has.

Ichor Rats

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
When Ichor Rats enters the battlefield, each player gets a poison counter.

Virulent Wound

Put a -1/-1 counter on target creature. When that creature dies this turn, its controller gets a poison counter.

Cabal Ritual

Add {B}{B}{B}.
Threshold — Add {B}{B}{B}{B}{B} instead if seven or more cards are in your graveyard.

Snap

Return target creature to its owner's hand. Untap up to two lands.

Necrogen Communion

Enchant creature you control
Enchanted creature has toxic 2. (Players dealt combat damage by it also get two poison counters.)
When enchanted creature dies, return that card to the battlefield under your control.

Dark Ritual

Inkmoth Nexus

{T}: Add {C}.
{1}: Inkmoth Nexus becomes a 1/1 Phyrexian Blinkmoth artifact creature with flying and infect until end of turn. It's still a land. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Plague Myr

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{T}: Add {C}.

Private Research

Enchant creature
At the beginning of your upkeep, you may put a page counter on Private Research.
When enchanted creature dies, draw a card for each page counter on Private Research.

Pestilent Syphoner

Flying
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)

High Tide

Until end of turn, whenever a player taps an Island for mana, that player adds an additional {U}.

Rain of Filth

Until end of turn, lands you control gain "Sacrifice this land: Add {B}."

Unwind

Counter target noncreature spell. Untap up to three lands.

Night's Whisper

Notion Rain

Surveil 2, then draw two cards. Notion Rain deals 2 damage to you. (To surveil 2, look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Gruesome Realization

Choose one —
• You draw two cards and you lose 2 life.
• Creatures your opponents control get -1/-1 until end of turn.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Vexing Sphinx

Flying
Cumulative upkeep—Discard a card. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
When Vexing Sphinx dies, draw a card for each age counter on it.

Mindless Automaton

Mindless Automaton enters the battlefield with two +1/+1 counters on it.
{1}, Discard a card: Put a +1/+1 counter on Mindless Automaton.
Remove two +1/+1 counters from Mindless Automaton: Draw a card.

Benthic Biomancer

{1}{U}: Adapt 1. (If this creature has no +1/+1 counters on it, put a +1/+1 counter on it.)
Whenever one or more +1/+1 counters are put on Benthic Biomancer, draw a card, then discard a card.

Bring the Ending

Counter target spell unless its controller pays {2}.
Corrupted — Counter that spell instead if its controller has three or more poison counters.

Of One Mind

This spell costs {2} less to cast if you control a Human creature and a non-Human creature.
Draw two cards.

Preordain

Scry 2, then draw a card. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Ponder

Look at the top three cards of your library, then put them back in any order. You may shuffle.
Draw a card.

Scarscale Ritual

As an additional cost to cast this spell, put a -1/-1 counter on a creature you control.
Draw two cards.

Saprazzan Cove

Saprazzan Cove enters the battlefield tapped.
{T}: Put a storage counter on Saprazzan Cove.
{T}, Remove any number of storage counters from Saprazzan Cove: Add {U} for each storage counter removed this way.

Chained Throatseeker

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Chained Throatseeker can't attack unless defending player is poisoned.

Reaper of Sheoldred

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever a source deals damage to Reaper of Sheoldred, that source's controller gets a poison counter.

Dreadship Reef

{T}: Add {C}.
{1}, {T}: Put a storage counter on Dreadship Reef.
{1}, Remove X storage counters from Dreadship Reef: Add X mana in any combination of {U} and/or {B}.

Gemstone Mine

Gemstone Mine enters the battlefield with three mining counters on it.
{T}, Remove a mining counter from Gemstone Mine: Add one mana of any color. If there are no mining counters on Gemstone Mine, sacrifice it.

Anoint with Affliction

Exile target creature if it has mana value 3 or less.
Corrupted — Exile that creature instead if its controller has three or more poison counters.

Temple of Deceit

Temple of Deceit enters the battlefield tapped.
When Temple of Deceit enters the battlefield, scry 1.
{T}: Add {U} or {B}.

Bottomless Vault

Bottomless Vault enters the battlefield tapped.
You may choose not to untap Bottomless Vault during your untap step.
At the beginning of your upkeep, if Bottomless Vault is tapped, put a storage counter on it.
{T}, Remove any number of storage counters from Bottomless Vault: Add {B} for each storage counter removed this way.

Command Tower

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Sunken Hollow

({T}: Add {U} or {B}.)
Sunken Hollow enters the battlefield tapped unless you control two or more basic lands.

Peat Bog

Peat Bog enters the battlefield tapped with two depletion counters on it.
{T}, Remove a depletion counter from Peat Bog: Add {B}{B}. If there are no depletion counters on Peat Bog, sacrifice it.

Saprazzan Skerry

Saprazzan Skerry enters the battlefield tapped with two depletion counters on it.
{T}, Remove a depletion counter from Saprazzan Skerry: Add {U}{U}. If there are no depletion counters on Saprazzan Skerry, sacrifice it.

Subterranean Hangar

Subterranean Hangar enters the battlefield tapped.
{T}: Put a storage counter on Subterranean Hangar.
{T}, Remove any number of storage counters from Subterranean Hangar: Add {B} for each storage counter removed this way.

Sand Silos

Sand Silos enters the battlefield tapped.
You may choose not to untap Sand Silos during your untap step.
At the beginning of your upkeep, if Sand Silos is tapped, put a storage counter on it.
{T}, Remove any number of storage counters from Sand Silos: Add {U} for each storage counter removed this way.

Dimir Aqueduct

Dimir Aqueduct enters the battlefield tapped.
When Dimir Aqueduct enters the battlefield, return a land you control to its owner's hand.
{T}: Add {U}{B}.

Mage-Ring Network

{T}: Add {C}.
{1}, {T}: Put a storage counter on Mage-Ring Network.
{T}, Remove any number of storage counters from Mage-Ring Network: Add {C} for each storage counter removed this way.

Darkwater Catacombs

Choked Estuary

As Choked Estuary enters the battlefield, you may reveal an Island or Swamp card from your hand. If you don't, Choked Estuary enters the battlefield tapped.
{T}: Add {U} or {B}.

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