Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Liesa, Shroud of Dusk

Rather than pay {2} for each previous time you've cast this spell from the command zone this game, pay 2 life that many times.
Flying, lifelink
Whenever a player casts a spell, they lose 2 life.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Indulging Patrician

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your end step, if you gained 3 or more life this turn, each opponent loses 3 life.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters the battlefield, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Markov Purifier

Lifelink
At the beginning of your end step, if you gained life this turn, you may pay {2}. If you do, draw a card.

Angel of Destiny

Flying, double strike
Whenever a creature you control deals combat damage to a player, you and that player each gain that much life.
At the beginning of your end step, if you have at least 15 life more than your starting life total, each player Angel of Destiny attacked this turn loses the game.

Authority of the Consuls

Creatures your opponents control enter the battlefield tapped.
Whenever a creature enters the battlefield under an opponent's control, you gain 1 life.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Path of Ancestry

Path of Ancestry enters the battlefield tapped.
{T}: Add one mana of any color in your commander's color identity. When that mana is spent to cast a creature spell that shares a creature type with your commander, scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Kunoros, Hound of Athreos

Vigilance, menace, lifelink
Creature cards in graveyards can't enter the battlefield.
Players can't cast spells from graveyards.

Felidar Sovereign

Vigilance, lifelink
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature and you return up to one target creature card from your graveyard to your hand.

Mortify

Temple of Silence

Temple of Silence enters the battlefield tapped.
When Temple of Silence enters the battlefield, scry 1.
{T}: Add {W} or {B}.

Sunscorch Regent

Flying
Whenever an opponent casts a spell, put a +1/+1 counter on Sunscorch Regent and you gain 1 life.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Tainted Sigil

{T}, Sacrifice Tainted Sigil: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Command Tower

Isolated Chapel

Isolated Chapel enters the battlefield tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Gift of Immortality

Enchant creature
When enchanted creature dies, return that card to the battlefield under its owner's control. Return Gift of Immortality to the battlefield attached to that creature at the beginning of the next end step.

Nightmare's Thirst

You gain 1 life. Target creature gets -X/-X until end of turn, where X is the amount of life you gained this turn.

Fountain of Renewal

At the beginning of your upkeep, you gain 1 life.
{3}, Sacrifice Fountain of Renewal: Draw a card.

Charcoal Diamond

Charcoal Diamond enters the battlefield tapped.
{T}: Add {B}.

Marble Diamond

Marble Diamond enters the battlefield tapped.
{T}: Add {W}.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Divinity of Pride

Flying, lifelink
Divinity of Pride gets +4/+4 as long as you have 25 or more life.

Kaya's Wrath

Destroy all creatures. You gain life equal to the number of creatures you controlled that were destroyed this way.

Revival

Return target creature card with mana value 3 or less from your graveyard to the battlefield.

Revenge

Double your life total. Target opponent loses half their life, rounded up.

Revival // Revenge

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Court of Ambition

When Court of Ambition enters the battlefield, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Radiant Fountain

When Radiant Fountain enters the battlefield, you gain 2 life.
{T}: Add {C}.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Boon Reflection

If you would gain life, you gain twice that much life instead.

Font of Agonies

Whenever you pay life, put that many blood counters on Font of Agonies.
{1}{B}, Remove four blood counters from Font of Agonies: Destroy target creature.

Orzhov Signet

Pristine Talisman

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Worn Powerstone

Worn Powerstone enters the battlefield tapped.
{T}: Add {C}{C}.

Bojuka Bog

Bojuka Bog enters the battlefield tapped.
When Bojuka Bog enters the battlefield, exile target player's graveyard.
{T}: Add {B}.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Bounty Agent

Vigilance
{T}, Sacrifice Bounty Agent: Destroy target legendary permanent that's an artifact, creature, or enchantment.

Cathar Commando

Flash
{1}, Sacrifice Cathar Commando: Destroy target artifact or enchantment.

Veinwitch Coven

Menace
Whenever you gain life, you may pay {B}. If you do, return target creature card from your graveyard to your hand.

Crested Sunmare

Other Horses you control have indestructible.
At the beginning of each end step, if you gained life this turn, create a 5/5 white Horse creature token.

Soul Link

Enchant creature
Whenever enchanted creature deals damage, you gain that much life.
Whenever enchanted creature is dealt damage, you gain that much life.

Soul Channeling

Enchant creature
Pay 2 life: Regenerate enchanted creature.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Swamp

Serene Master

Whenever Serene Master blocks, exchange its power and the power of target creature it's blocking until end of combat.

Spirit Link

Enchant creature (Target a creature as you cast this. This card enters the battlefield attached to that creature.)
Whenever enchanted creature deals damage, you gain that much life.

Plains

Dawn of Hope

Whenever you gain life, you may pay {2}. If you do, draw a card.
{3}{W}: Create a 1/1 white Soldier creature token with lifelink.

Sun Droplet

Whenever you're dealt damage, put that many charge counters on Sun Droplet.
At the beginning of each upkeep, you may remove a charge counter from Sun Droplet. If you do, you gain 1 life.

Profane Procession

{3}{W}{B}: Exile target creature. Then if there are three or more cards exiled with Profane Procession, transform it.

Tomb of the Dusk Rose

(Transforms from Profane Procession.)
{T}: Add one mana of any color.
{2}{W}{B}, {T}: Put a creature card exiled with this permanent onto the battlefield under your control.

Profane Procession // Tomb of the Dusk Rose

Sol Ring

Infernal Grasp

Destroy target creature. You lose 2 life.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Xander's Pact

Casualty 2 (As you cast this spell, you may sacrifice a creature with power 2 or greater. When you do, copy this spell.)
Each opponent exiles the top card of their library. You may cast spells from among those cards this turn. If you cast a spell this way, pay life equal to that spell's mana value rather than pay its mana cost.

Children of Korlis

Sacrifice Children of Korlis: You gain life equal to the life you've lost this turn. (Damage causes loss of life.)

Selfless Glyphweaver

Exile Selfless Glyphweaver: Creatures you control gain indestructible until end of turn.

Deadly Vanity

Choose a creature or planeswalker, then destroy all other creatures and planeswalkers.

Selfless Glyphweaver // Deadly Vanity

Moon-Blessed Cleric

Divine Intervention — When Moon-Blessed Cleric enters the battlefield, you may search your library for an enchantment card, reveal it, then shuffle and put that card on top.

Stinging Study

You draw X cards and you lose X life, where X is the mana value of a commander you own on the battlefield or in the command zone.

Pact Weapon

As long as Pact Weapon is attached to a creature, you don't lose the game for having 0 or less life.
Whenever equipped creature attacks, draw a card and reveal it. The creature gets +X/+X until end of turn and you lose X life, where X is that card's mana value.
Equip—Discard a card.

Sign in Blood

Target player draws two cards and loses 2 life.

Night's Whisper

Read the Bones

Scry 2, then draw two cards. You lose 2 life.

Essence Pulse

You gain 2 life. Each creature gets -X/-X until end of turn, where X is the amount of life you gained this turn.

Bad Deal

You draw two cards and each opponent discards two cards. Each player loses 2 life.

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