Depopulate

Each player who controls a multicolored creature draws a card. Then destroy all creatures.

Armageddon

Worldslayer

Whenever equipped creature deals combat damage to a player, destroy all permanents other than Worldslayer.
Equip {5} ({5}: Attach to target creature you control. Equip only as a sorcery.)

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Slash the Ranks

Destroy all creatures and planeswalkers except for commanders.

Kirtar's Wrath

Destroy all creatures. They can't be regenerated.
Threshold — If seven or more cards are in your graveyard, instead destroy all creatures, then create two 1/1 white Spirit creature tokens with flying. Creatures destroyed this way can't be regenerated.

Wrath of God

Destroy all creatures. They can't be regenerated.

Catastrophe

Destroy all lands or all creatures. Creatures destroyed this way can't be regenerated.

Ravages of War

Rout

You may cast Rout as though it had flash if you pay {2} more to cast it. (You may cast it any time you could cast an instant.)
Destroy all creatures. They can't be regenerated.

Magus of the Disk

Magus of the Disk enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Sunscour

You may exile two white cards from your hand rather than pay this spell's mana cost.
Destroy all creatures.

Cataclysm

Each player chooses from among the permanents they control an artifact, a creature, an enchantment, and a land, then sacrifices the rest.

Ondu Inversion

Ondu Skyruins

Ondu Skyruins enters tapped.
{T}: Add {W}.

Ondu Inversion // Ondu Skyruins

White Sun's Twilight

You gain X life. Create X 1/1 colorless Phyrexian Mite artifact creature tokens with toxic 1 and "This creature can't block." If X is 5 or more, destroy all other creatures. (Players dealt combat damage by a creature with toxic 1 also get a poison counter.)

Phyrexian Rebirth

Destroy all creatures, then create an X/X colorless Phyrexian Horror artifact creature token, where X is the number of creatures destroyed this way.

No Witnesses

Each player who controls the most creatures investigates. Then destroy all creatures. (To investigate, create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")

Shatter the Sky

Each player who controls a creature with power 4 or greater draws a card. Then destroy all creatures.

Martial Coup

Create X 1/1 white Soldier creature tokens. If X is 5 or more, destroy all other creatures.

Mass Calcify

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Ravnica at War

Generous Gift

Destroy target permanent. Its controller creates a 3/3 green Elephant creature token.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

All Is Dust

Each player sacrifices all permanents they control that are one or more colors.

Elspeth, Sun's Champion

+1: Create three 1/1 white Soldier creature tokens.
−3: Destroy all creatures with power 4 or greater.
−7: You get an emblem with "Creatures you control get +2/+2 and have flying."

Balancing Act

Each player chooses a number of permanents they control equal to the number of permanents controlled by the player who controls the fewest, then sacrifices the rest. Each player discards cards the same way.

Avacyn, Angel of Hope

Flying, vigilance, indestructible
Other permanents you control have indestructible.

Boompile

{T}: Flip a coin. If you win the flip, destroy all nonland permanents.

By Invitation Only

Choose a number between 0 and 13. Each player sacrifices that many creatures of their choice.

Expel the Interlopers

Choose a number between 0 and 10. Destroy all creatures with power greater than or equal to the chosen number.

Doomskar

Destroy all creatures.
Foretell {1}{W}{W} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Fortunate Few

Choose a nonland permanent you don't control, then each other player chooses a nonland permanent they don't control that hasn't been chosen this way. Destroy all other nonland permanents.

Fated Retribution

Destroy all creatures and planeswalkers. If it's your turn, scry 2.

Global Ruin

Each player chooses from the lands they control a land of each basic land type, then sacrifices the rest.

Fell the Mighty

Destroy all creatures with power greater than target creature's power.

Cleansing

For each land, destroy that land unless any player pays 1 life.

Cleansing Meditation

Destroy all enchantments.
Threshold — If seven or more cards are in your graveyard, instead destroy all enchantments, then return all cards in your graveyard destroyed this way to the battlefield.

Cleansing Nova

Choose one —
• Destroy all creatures.
• Destroy all artifacts and enchantments.

Crisis of Conscience

Choose one —
• Destroy all tokens.
• Destroy all nonland, nontoken permanents.

Damning Verdict

Destroy all creatures with no counters on them.

Day of Judgment

Dusk

Destroy all creatures with power 3 or greater.

Dawn

Aftermath (Cast this spell only from your graveyard. Then exile it.)
Return all creature cards with power 2 or less from your graveyard to your hand.

Dusk // Dawn

End Hostilities

Destroy all creatures and all permanents attached to creatures.

Dismantling Wave

For each opponent, destroy up to one target artifact or enchantment that player controls.
Cycling {6}{W}{W} ({6}{W}{W}, Discard this card: Draw a card.)
When you cycle Dismantling Wave, destroy all artifacts and enchantments.

Dimensional Breach

Exile all permanents. For as long as any of those cards remain exiled, at the beginning of each player's upkeep, that player returns one of the exiled cards they own to the battlefield.

Hour of Revelation

This spell costs {3} less to cast if there are ten or more nonland permanents on the battlefield.
Destroy all nonland permanents.

March of Souls

Destroy all creatures. They can't be regenerated. For each creature destroyed this way, its controller creates a 1/1 white Spirit creature token with flying.

Paraselene

Destroy all enchantments. You gain 1 life for each enchantment destroyed this way.

Planar Cleansing

Planar Outburst

Destroy all nonland creatures.
Awaken 4—{5}{W}{W}{W} (If you cast this spell for {5}{W}{W}{W}, also put four +1/+1 counters on target land you control and it becomes a 0/0 Elemental creature with haste. It's still a land.)

Play of the Game

Assist (Another player can pay up to {6} of this spell's cost.)
Exile all nonland permanents.

Soulscour

Retribution of the Meek

Destroy all creatures with power 4 or greater. They can't be regenerated.

Retaliate

Destroy all creatures that dealt damage to you this turn.

Serenity

At the beginning of your upkeep, destroy all artifacts and enchantments. They can't be regenerated.

Solar Tide

Choose one —
• Destroy all creatures with power 2 or less.
• Destroy all creatures with power 3 or greater.
Entwine—Sacrifice two lands. (Choose both if you pay the entwine cost.)

Restore Balance

Suspend 6—{W}
Each player chooses a number of lands they control equal to the number of lands controlled by the player who controls the fewest, then sacrifices the rest. Players sacrifice creatures and discard cards the same way.

Guan Yu's 1,000-Li March

Hour of Reckoning

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Destroy all nontoken creatures.

Tempest of Light

Vanquish the Horde

This spell costs {1} less to cast for each creature on the battlefield.
Destroy all creatures.

Wave of Reckoning

Each creature deals damage to itself equal to its power.

Winds of Rath

Destroy all creatures that aren't enchanted. They can't be regenerated.

Citywide Bust

Destroy all creatures with toughness 4 or greater.

Planar Collapse

At the beginning of your upkeep, if there are four or more creatures on the battlefield, sacrifice Planar Collapse and destroy all creatures. They can't be regenerated.

Kor Haven

{T}: Add {C}.
{1}{W}, {T}: Prevent all combat damage that would be dealt by target attacking creature this turn.

Abu Ja'far

When Abu Ja'far dies, destroy all creatures blocking or blocked by it. They can't be regenerated.

Plains

Karoo

Karoo enters tapped.
When Karoo enters, sacrifice it unless you return an untapped Plains you control to its owner's hand.
{T}: Add {C}{W}.

Farewell

Choose one or more —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all graveyards.

Lotus Field

Hexproof
Lotus Field enters tapped.
When Lotus Field enters, sacrifice two lands.
{T}: Add three mana of any one color.

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