Seizan, Perverter of Truth

At the beginning of each player's upkeep, that player loses 2 life and draws two cards.

Demon of Loathing

Flying, trample
Whenever Demon of Loathing deals combat damage to a player, that player sacrifices a creature of their choice.

Reiver Demon

Flying
When Reiver Demon enters, if you cast it from your hand, destroy all nonartifact, nonblack creatures. They can't be regenerated.

Ob Nixilis, Unshackled

Flying, trample
Whenever an opponent searches their library, that player sacrifices a creature of their choice and loses 10 life.
Whenever another creature dies, put a +1/+1 counter on Ob Nixilis, Unshackled.

Rune-Scarred Demon

Flying
When this creature enters, search your library for a card, put it into your hand, then shuffle.

Archon of Cruelty

Flying
Whenever Archon of Cruelty enters or attacks, target opponent sacrifices a creature or planeswalker of their choice, discards a card, and loses 3 life. You draw a card and gain 3 life.

Gelatinous Cube

Engulf — When Gelatinous Cube enters, exile target non-Ooze creature an opponent controls until Gelatinous Cube leaves the battlefield.
Dissolve — {X}{B}: Put target creature card with mana value X exiled with Gelatinous Cube into its owner's graveyard.

Nimana Skitter-Sneak

As long as an opponent has eight or more cards in their graveyard, Nimana Skitter-Sneak gets +1/+0 and has menace. (It can't be blocked except by two or more creatures.)

Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Relic Bane

Enchant artifact
Enchanted artifact has "At the beginning of your upkeep, you lose 2 life."

Swamp

Koma's Faithful

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
When Koma's Faithful dies, each player mills three cards. (They each put the top three cards of their library into their graveyard.)

Kagemaro, First to Suffer

Kagemaro, First to Suffer's power and toughness are each equal to the number of cards in your hand.
{B}, Sacrifice Kagemaro: All creatures get -X/-X until end of turn, where X is the number of cards in your hand.

Junji, the Midnight Sky

Flying, menace
When Junji, the Midnight Sky dies, choose one —
• Each opponent discards two cards and loses 2 life.
• Put target non-Dragon creature card from a graveyard onto the battlefield under your control. You lose 2 life.

Blood Pact

Target player draws two cards and loses 2 life.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Murder

Decanter of Endless Water

You have no maximum hand size.
{T}: Add one mana of any color.

Barren Moor

Barren Moor enters tapped.
{T}: Add {B}.
Cycling {B} ({B}, Discard this card: Draw a card.)

Ob Nixilis, the Hate-Twisted

Whenever an opponent draws a card, Ob Nixilis, the Hate-Twisted deals 1 damage to that player.
−2: Destroy target creature. Its controller draws two cards.

Tainted Remedy

If an opponent would gain life, that player loses that much life instead.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Howling Mine

At the beginning of each player's draw step, if Howling Mine is untapped, that player draws an additional card.

Prophetic Prism

When Prophetic Prism enters, draw a card.
{1}, {T}: Add one mana of any color.

Dark Deal

Each player discards all the cards in their hand, then draws that many cards minus one.

Ultimate Price

Charcoal Diamond

Charcoal Diamond enters tapped.
{T}: Add {B}.

Hero's Downfall

Ebony Owl Netsuke

At the beginning of each opponent's upkeep, if that player has seven or more cards in hand, Ebony Owl Netsuke deals 4 damage to that player.

Eldritch Pact

Target player draws X cards and loses X life, where X is the number of cards in their graveyard.

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Skull Storm

When you cast this spell, copy it for each time you've cast your commander from the command zone this game.
Each opponent sacrifices a creature of their choice. Each opponent who can't loses half their life, rounded up.

Baneful Omen

At the beginning of your end step, you may reveal the top card of your library. If you do, each opponent loses life equal to that card's mana value.

Infernal Grasp

Destroy target creature. You lose 2 life.

Skullcage

At the beginning of each opponent's upkeep, Skullcage deals 2 damage to that player unless they have exactly three or exactly four cards in hand.

Warlock Class

(Gain the next level as a sorcery to add its ability.)
At the beginning of your end step, if a creature died this turn, each opponent loses 1 life.
{1}{B}: Level 2
When this Class becomes level 2, look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.
{6}{B}: Level 3
At the beginning of your end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Ambition's Cost

You draw three cards and you lose 3 life.

Summon Undead

You may mill three cards. Then return a creature card from your graveyard to the battlefield. (To mill a card, put the top card of your library into your graveyard.)

Spellbook

Invoke Despair

Target opponent sacrifices a creature of their choice. If they can't, they lose 2 life and you draw a card. Then repeat this process for an enchantment and a planeswalker.

Doom Blade

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Font of Mythos

At the beginning of each player's draw step, that player draws two additional cards.

Iron Maiden

At the beginning of each opponent's upkeep, Iron Maiden deals X damage to that player, where X is the number of cards in their hand minus 4.

Temporal Extortion

When you cast this spell, any player may pay half their life, rounded up. If a player does, counter Temporal Extortion.
Take an extra turn after this one.

Dogged Pursuit

At the beginning of your end step, each opponent loses 1 life and you gain 1 life.

Atrocious Experiment

Target player mills two cards, draws two cards, and loses 2 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Ivory Tower

At the beginning of your upkeep, you gain X life, where X is the number of cards in your hand minus 4.

Viseling

At the beginning of each opponent's upkeep, Viseling deals X damage to that player, where X is the number of cards in their hand minus 4.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Court of Ambition

When Court of Ambition enters, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Price of Knowledge

Players have no maximum hand size.
At the beginning of each opponent's upkeep, Price of Knowledge deals damage to that player equal to the number of cards in that player's hand.

Venser's Journal

You have no maximum hand size.
At the beginning of your upkeep, you gain 1 life for each card in your hand.

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Soul Shatter

Each opponent sacrifices a creature or planeswalker with the highest mana value among creatures and planeswalkers they control.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Profane Transfusion

Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Elder Brain

Menace
Whenever Elder Brain attacks a player, exile all cards from that player's hand, then they draw that many cards. You may play lands and cast spells from among the exiled cards for as long as they remain exiled. If you cast a spell this way, you may spend mana as though it were mana of any color to cast it.

Hedonist's Trove

When Hedonist's Trove enters, exile target opponent's graveyard.
You may play lands from among cards exiled with Hedonist's Trove.
You may cast spells from among cards exiled with Hedonist's Trove. You can't cast more than one spell this way each turn.

Keening Stone

{5}, {T}: Target player mills X cards, where X is the number of cards in that player's graveyard.

Archfiend of Depravity

Flying
At the beginning of each opponent's end step, that player chooses up to two creatures they control, then sacrifices the rest.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Fleshbag Marauder

When Fleshbag Marauder enters, each player sacrifices a creature of their choice.

Master of the Feast

Flying
At the beginning of your upkeep, each opponent draws a card.

Indulgent Tormentor

Flying
At the beginning of your upkeep, draw a card unless target opponent sacrifices a creature of their choice or pays 3 life.

Sheoldred, Whispering One

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.
At the beginning of each opponent's upkeep, that player sacrifices a creature of their choice.

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