Persistent Constrictor

At the beginning of each opponent's upkeep, they lose 1 life and you put a -1/-1 counter on up to one target creature they control.
Persist (When this creature dies, if it had no -1/-1 counters on it, return it to the battlefield under its owner's control with a -1/-1 counter on it.)

Necrogen Rotpriest

Toxic 2 (Players dealt combat damage by this creature also get two poison counters.)
Whenever a creature you control with toxic deals combat damage to a player, that player gets an additional poison counter.
{1}{B}{G}: Target creature you control with toxic gains deathtouch until end of turn.

Vraska's Fall

Each opponent sacrifices a creature or planeswalker of their choice and gets a poison counter.

Unnatural Restoration

Return target permanent card from your graveyard to your hand. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Indatha Triome

({T}: Add {W}, {B}, or {G}.)
Indatha Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Glistening Sphere

Glistening Sphere enters tapped.
When Glistening Sphere enters, proliferate.
{T}: Add one mana of any color.
Corrupted — {T}: Add three mana of any one color. Activate only if an opponent has three or more poison counters.

Phyresis

Enchant creature
Enchanted creature has infect. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Birds of Paradise

Zagoth Triome

({T}: Add {B}, {G}, or {U}.)
Zagoth Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

The Ozolith

Whenever a creature you control leaves the battlefield, if it had counters on it, put those counters on The Ozolith.
At the beginning of combat on your turn, if The Ozolith has counters on it, you may move all counters from The Ozolith onto target creature.

Doubling Season

If an effect would create one or more tokens under your control, it creates twice that many of those tokens instead.
If an effect would put one or more counters on a permanent you control, it puts twice that many of those counters on that permanent instead.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Contagion Engine

When Contagion Engine enters, put a -1/-1 counter on each creature target player controls.
{4}, {T}: Proliferate twice. (Choose any number of permanents and/or players, then give each another counter of each kind already there. Then do it again.)

Conqueror's Flail

Equipped creature gets +1/+1 for each color among permanents you control.
As long as Conqueror's Flail is attached to a creature, your opponents can't cast spells during your turn.
Equip {2}

Shadowspear

Equipped creature gets +1/+1 and has trample and lifelink.
{1}: Permanents your opponents control lose hexproof and indestructible until end of turn.
Equip {2}

Deepglow Skate

When Deepglow Skate enters, double the number of each kind of counter on any number of target permanents.

Vishgraz, the Doomhive

Menace, toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When Vishgraz, the Doomhive enters, create three 1/1 colorless Phyrexian Mite artifact creature tokens with toxic 1 and "This creature can't block."
Vishgraz gets +1/+1 for each poison counter your opponents have.

Evolution Sage

Landfall — Whenever a land you control enters, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Voidwing Hybrid

Flying
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When you proliferate, return Voidwing Hybrid from your graveyard to your hand.

Ixhel, Scion of Atraxa

Flying, vigilance, toxic 2
Corrupted — At the beginning of your end step, each opponent who has three or more poison counters exiles the top card of their library face down. You may look at and play those cards for as long as they remain exiled, and you may spend mana as though it were mana of any color to cast those spells.

Bloodroot Apothecary

Toxic 2 (Players dealt combat damage by this creature also get two poison counters. A player with ten or more poison counters loses the game.)
When Bloodroot Apothecary enters, you and target opponent each create a Treasure token.
Whenever an opponent sacrifices a noncreature token, that player gets two poison counters.

Infectious Bite

Target creature you control deals damage equal to its power to target creature you don't control. Each opponent gets a poison counter.

Inexorable Tide

Whenever you cast a spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Caress of Phyrexia

Target player draws three cards, loses 3 life, and gets three poison counters.

Mossborn Hydra

Trample (This creature can deal excess combat damage to the player or planeswalker it's attacking.)
This creature enters with a +1/+1 counter on it.
Landfall — Whenever a land you control enters, double the number of +1/+1 counters on this creature.

Drown in Ichor

Target creature gets -4/-4 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Norn's Decree

Whenever one or more creatures an opponent controls deal combat damage to you, that opponent gets a poison counter.
Whenever a player attacks, if one or more players being attacked are poisoned, the attacking player draws a card.

Phyresis Outbreak

Each opponent gets a poison counter. Then each creature your opponents control gets -1/-1 until end of turn for each poison counter its controller has.

Skrelv, Defector Mite

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
Skrelv, Defector Mite can't block.
{W/P}, {T}: Choose a color. Another target creature you control gains toxic 1 and hexproof from that color until end of turn. It can't be blocked by creatures of that color this turn. ({W/P} can be paid with either {W} or 2 life.)

Flux Channeler

Whenever you cast a noncreature spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Phyrexian Swarmlord

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
At the beginning of your upkeep, create a 1/1 green Phyrexian Insect creature token with infect for each poison counter your opponents have.

Mutational Advantage

Permanents you control with counters on them gain hexproof and indestructible until end of turn. Prevent all damage that would be dealt to those permanents this turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Atomize

Destroy target nonland permanent. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Assassin's Trophy

Destroy target permanent an opponent controls. Its controller may search their library for a basic land card, put it onto the battlefield, then shuffle.

Sword of Light and Shadow

Equipped creature gets +2/+2 and has protection from white and from black.
Whenever equipped creature deals combat damage to a player, you gain 3 life and you may return up to one target creature card from your graveyard to your hand.
Equip {2}

Norn's Choirmaster

Flying, first strike
Whenever a commander you control enters or attacks, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Experimental Augury

Look at the top three cards of your library. Put one of them into your hand and the rest on the bottom of your library in any order. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Whispersilk Cloak

Equipped creature can't be blocked and has shroud. (It can't be the target of spells or abilities.)
Equip {2}

Venerated Rotpriest

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
Whenever a creature you control becomes the target of a spell, target opponent gets a poison counter.

Atraxa, Praetors' Voice

Flying, vigilance, deathtouch, lifelink
At the beginning of your end step, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Contaminant Grafter

Trample, toxic 1
Whenever one or more creatures you control deal combat damage to one or more players, proliferate.
Corrupted — At the beginning of your end step, if an opponent has three or more poison counters, draw a card, then you may put a land card from your hand onto the battlefield.

Tezzeret's Gambit

({U/P} can be paid with either {U} or 2 life.)
Draw two cards, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Propaganda

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Thrummingbird

Flying
Whenever Thrummingbird deals combat damage to a player, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Simic Ascendancy

{1}{G}{U}: Put a +1/+1 counter on target creature you control.
Whenever one or more +1/+1 counters are put on a creature you control, put that many growth counters on Simic Ascendancy.
At the beginning of your upkeep, if Simic Ascendancy has twenty or more growth counters on it, you win the game.

Innkeeper's Talent

(Gain the next level as a sorcery to add its ability.)
At the beginning of combat on your turn, put a +1/+1 counter on target creature you control.
{G}: Level 2
Permanents you control with counters on them have ward {1}.
{3}{G}: Level 3
If you would put one or more counters on a permanent or player, put twice that many of each of those kinds of counters on that permanent or player instead.

Court of Garenbrig

When Court of Garenbrig enters, you become the monarch.
At the beginning of your upkeep, distribute two +1/+1 counters among up to two target creatures. Then if you're the monarch, double the number of +1/+1 counters on each creature you control.

Ezuri, Stalker of Spheres

When Ezuri, Stalker of Spheres enters, you may pay {3}. If you do, proliferate twice.
Whenever you proliferate, draw a card.

Tainted Observer

Flying
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
Whenever another creature you control enters, you may pay {2}. If you do, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Hardened Scales

If one or more +1/+1 counters would be put on a creature you control, that many plus one +1/+1 counters are put on it instead.

Command Tower

Ghostly Prison

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Raffine's Tower

({T}: Add {W}, {U}, or {B}.)
Raffine's Tower enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Seaside Citadel

Seaside Citadel enters tapped.
{T}: Add {G}, {W}, or {U}.

Lae'zel, Vlaakith's Champion

If you would put one or more counters on a creature or planeswalker you control or on yourself, put that many plus one of each of those kinds of counters on that permanent or player instead.
Choose a Background (You can have a Background as a second commander.)

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Tekuthal, Inquiry Dominus

Flying
If you would proliferate, proliferate twice instead.
{1}{U/P}{U/P}, Remove three counters from among other artifacts, creatures, and planeswalkers you control: Put an indestructible counter on Tekuthal, Inquiry Dominus. ({U/P} can be paid with either {U} or 2 life.)

Prologue to Phyresis

Each opponent gets a poison counter.
Draw a card.

Ajani, Sleeper Agent

Compleated ({G/W/P} can be paid with {G}, {W}, or 2 life. If life was paid, this planeswalker enters with two fewer loyalty counters.)
+1: Reveal the top card of your library. If it's a creature or planeswalker card, put it into your hand. Otherwise, you may put it on the bottom of your library.
−3: Distribute three +1/+1 counters among up to three target creatures. They gain vigilance until end of turn.
−6: You get an emblem with "Whenever you cast a creature or planeswalker spell, target opponent gets two poison counters."

Sandsteppe Citadel

Sandsteppe Citadel enters tapped.
{T}: Add {W}, {B}, or {G}.

Vorinclex, Monstrous Raider

Trample, haste
If you would put one or more counters on a permanent or player, put twice that many of each of those kinds of counters on that permanent or player instead.
If an opponent would put one or more counters on a permanent or player, they put half that many of each of those kinds of counters on that permanent or player instead, rounded down.

Ichor Rats

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
When Ichor Rats enters, each player gets a poison counter.

Blightbelly Rat

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When Blightbelly Rat dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Opulent Palace

Opulent Palace enters tapped.
{T}: Add {B}, {G}, or {U}.

Skithiryx, the Blight Dragon

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{B}: Skithiryx, the Blight Dragon gains haste until end of turn.
{B}{B}: Regenerate Skithiryx.

Cultivate

Search your library for up to two basic land cards, reveal those cards, put one onto the battlefield tapped and the other into your hand, then shuffle.

Bloated Contaminator

Trample
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
Whenever Bloated Contaminator deals combat damage to a player, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Arcane Sanctum

Arcane Sanctum enters tapped.
{T}: Add {W}, {U}, or {B}.

Brokers Ascendancy

At the beginning of your end step, put a +1/+1 counter on each creature you control and a loyalty counter on each planeswalker you control.

Karn's Bastion

{T}: Add {C}.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Cankerbloom

{1}, Sacrifice Cankerbloom: Choose one —
• Destroy target artifact.
• Destroy target enchantment.
• Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Chromatic Lantern

Lands you control have "{T}: Add one mana of any color."
{T}: Add one mana of any color.

Counterspell

Necrogen Communion

Enchant creature you control
Enchanted creature has toxic 2. (Players dealt combat damage by it also get two poison counters.)
When enchanted creature dies, return that card to the battlefield under your control.

Metastatic Evangel

Whenever another nontoken creature you control enters, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)