Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Voice of the Blessed

Whenever you gain life, put a +1/+1 counter on Voice of the Blessed.
As long as Voice of the Blessed has four or more +1/+1 counters on it, it has flying and vigilance.
As long as Voice of the Blessed has ten or more +1/+1 counters on it, it has indestructible.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Alabaster Mage

{1}{W}: Target creature you control gains lifelink until end of turn. (Damage dealt by the creature also causes its controller to gain that much life.)

Restless Fortress

Restless Fortress enters tapped.
{T}: Add {W} or {B}.
{2}{W}{B}: Restless Fortress becomes a 1/4 white and black Nightmare creature until end of turn. It's still a land.
Whenever Restless Fortress attacks, defending player loses 2 life and you gain 2 life.

Death Grasp

Death Grasp deals X damage to any target. You gain X life.

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter tapped.

Elixir of Immortality

{2}, {T}: You gain 5 life. Shuffle Elixir of Immortality and your graveyard into their owner's library.

Aegis Angel

Flying (This creature can't be blocked except by creatures with flying or reach.)
When Aegis Angel enters, another target permanent gains indestructible for as long as you control Aegis Angel. (Effects that say "destroy" don't destroy it. A creature with indestructible can't be destroyed by damage.)

Makeshift Binding

When Makeshift Binding enters, exile target creature an opponent controls until Makeshift Binding leaves the battlefield. You gain 2 life.

Demon's Horn

Whenever a player casts a black spell, you may gain 1 life.

Kaya, Orzhov Usurper

+1: Exile up to two target cards from a single graveyard. You gain 2 life if at least one creature card was exiled this way.
−1: Exile target nonland permanent with mana value 1 or less.
−5: Kaya, Orzhov Usurper deals damage to target player equal to the number of cards that player owns in exile and you gain that much life.

Starseer Mentor

Flying, vigilance
At the beginning of your end step, if you gained or lost life this turn, target opponent loses 3 life unless they sacrifice a nonland permanent or discard a card.

Doom Blade

Lunar Convocation

At the beginning of your end step, if you gained life this turn, each opponent loses 1 life.
At the beginning of your end step, if you gained and lost life this turn, create a 1/1 black Bat creature token with flying.
{1}{B}, Pay 2 life: Draw a card.

Edgar Markov's Coffin

At the beginning of your upkeep, create a 1/1 white and black Vampire creature token with lifelink and put a bloodline counter on Edgar Markov's Coffin. Then if there are three or more bloodline counters on it, remove those counters and transform it.

Edgar, Charmed Groom

Other Vampires you control get +1/+1.
When Edgar, Charmed Groom dies, return it to the battlefield transformed under its owner's control.

Edgar, Charmed Groom // Edgar Markov's Coffin

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Decree of Pain

Destroy all creatures. They can't be regenerated. Draw a card for each creature destroyed this way.
Cycling {3}{B}{B} ({3}{B}{B}, Discard this card: Draw a card.)
When you cycle Decree of Pain, all creatures get -2/-2 until end of turn.

Sorin, Vengeful Bloodlord

During your turn, creatures and planeswalkers you control have lifelink.
+2: Sorin, Vengeful Bloodlord deals 1 damage to target player or planeswalker.
−X: Return target creature card with mana value X from your graveyard to the battlefield. That creature is a Vampire in addition to its other types.

Sign in Blood

Target player draws two cards and loses 2 life.

Sanguine Savior

Flying, lifelink
Disguise {W/B}{W/B} (You may cast this card face down for {3} as a 2/2 creature with ward {2}. Turn it face up any time for its disguise cost.)
When Sanguine Savior is turned face up, another target creature you control gains lifelink until end of turn.

Stab Wound

Enchant creature
Enchanted creature gets -2/-2.
At the beginning of the upkeep of enchanted creature's controller, that player loses 2 life.

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Final Payment

As an additional cost to cast this spell, pay 5 life or sacrifice a creature or enchantment.
Destroy target creature.

Swamp

Asylum Visitor

At the beginning of each player's upkeep, if that player has no cards in hand, you draw a card and you lose 1 life.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Felidar Sovereign

Vigilance, lifelink
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Imp's Mischief

Change the target of target spell with a single target. You lose life equal to that spell's mana value.

Feast of the Victorious Dead

At the beginning of your end step, if one or more creatures died this turn, you gain that much life and distribute that many +1/+1 counters among creatures you control.

Chaplain's Blessing

Kaya, Intangible Slayer

Hexproof
+2: Each opponent loses 3 life and you gain 3 life.
0: You draw two cards. Then each opponent may scry 1.
−3: Exile target creature or enchantment. If it wasn't an Aura, create a token that's a copy of it, except it's a 1/1 white Spirit creature with flying in addition to its other types.

Sorin's Vengeance

Sorin's Vengeance deals 10 damage to target player or planeswalker and you gain 10 life.

Dawn of Hope

Whenever you gain life, you may pay {2}. If you do, draw a card.
{3}{W}: Create a 1/1 white Soldier creature token with lifelink.

Raven of Fell Omens

Flying
Whenever you commit a crime, each opponent loses 1 life and you gain 1 life. This ability triggers only once each turn. (Targeting opponents, anything they control, and/or cards in their graveyards is a crime.)

Stroke of Midnight

Destroy target nonland permanent. Its controller creates a 1/1 white Human creature token.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Caduceus, Staff of Hermes

Equipped creature has lifelink.
As long as you have 30 or more life, equipped creature gets +5/+5 and has indestructible and "Prevent all damage that would be dealt to this creature."
Equip {W}{W}

Sorin, Ravenous Neonate

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
+2: Create a Food token.
−1: Sorin, Ravenous Neonate deals damage equal to the amount of life you gained this turn to any target.
−6: Gain control of target creature. It becomes a Vampire in addition to its other types. Put a lifelink counter on it if you control a white permanent other than that creature or Sorin.

Sorin of House Markov

Lifelink
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
At the beginning of each of your postcombat main phases, if you gained 3 or more life this turn, exile Sorin of House Markov, then return him to the battlefield transformed under his owner's control.

Sorin of House Markov // Sorin, Ravenous Neonate

Memorial to Folly

Memorial to Folly enters tapped.
{T}: Add {B}.
{2}{B}, {T}, Sacrifice Memorial to Folly: Return target creature card from your graveyard to your hand.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Orzhov Signet

Nyx-Fleece Ram

At the beginning of your upkeep, you gain 1 life.

Forsaken Sanctuary

Forsaken Sanctuary enters tapped.
{T}: Add {W} or {B}.

Memorial to Glory

Memorial to Glory enters tapped.
{T}: Add {W}.
{3}{W}, {T}, Sacrifice Memorial to Glory: Create two 1/1 white Soldier creature tokens.

Legion Lieutenant

Plains

Call the Gatewatch

Search your library for a planeswalker card, reveal it, put it into your hand, then shuffle.

Murder

Grotesque Mutation

Target creature gets +3/+1 and gains lifelink until end of turn. (Damage dealt by the creature also causes its controller to gain that much life.)

Sorin, Lord of Innistrad

+1: Create a 1/1 black Vampire creature token with lifelink.
−2: You get an emblem with "Creatures you control get +1/+0."
−6: Destroy up to three target creatures and/or other planeswalkers. Return each card put into a graveyard this way to the battlefield under your control.

Sol Ring

Revitalize

Epicure of Blood

Whenever you gain life, each opponent loses 1 life.

Markov Purifier

Lifelink
At the beginning of your end step, if you gained life this turn, you may pay {2}. If you do, draw a card.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Curtains' Call

Undaunted (This spell costs {1} less to cast for each opponent.)
Destroy two target creatures.

Scoured Barrens

Scoured Barrens enters tapped.
When Scoured Barrens enters, you gain 1 life.
{T}: Add {W} or {B}.

Griffin Aerie

At the beginning of your end step, if you gained 3 or more life this turn, create a 2/2 white Griffin creature token with flying.

Age-Graced Chapel

Age-Graced Chapel enters tapped.
{T}: Add {W} or {B}.

Glasswing Grace

Enchant creature
Enchanted creature gets +2/+2 and has flying and lifelink.

Glasswing Grace // Age-Graced Chapel

Treasure Dredger

{1}, {T}, Pay 1 life: Create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Behold the Beyond

Discard your hand. Search your library for three cards, put them into your hand, then shuffle.

Essence Channeler

As long as you've lost life this turn, Essence Channeler has flying and vigilance.
Whenever you gain life, put a +1/+1 counter on Essence Channeler.
When Essence Channeler dies, put its counters on target creature you control.

Aurelia's Vindicator

Flying, lifelink, ward {2}
Disguise {X}{3}{W}
When Aurelia's Vindicator is turned face up, exile up to X other target creatures from the battlefield and/or creature cards from graveyards.
When Aurelia's Vindicator leaves the battlefield, return the exiled cards to their owners' hands.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)