Skithiryx, the Blight Dragon

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{B}: Skithiryx, the Blight Dragon gains haste until end of turn.
{B}{B}: Regenerate Skithiryx.

Vraska's Fall

Each opponent sacrifices a creature or planeswalker of their choice and gets a poison counter.

Necrogen Communion

Enchant creature you control
Enchanted creature has toxic 2. (Players dealt combat damage by it also get two poison counters.)
When enchanted creature dies, return that card to the battlefield under your control.

Withering Boon

As an additional cost to cast this spell, pay 3 life.
Counter target creature spell.

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik, Son of Yawgmoth.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Hatred

As an additional cost to cast this spell, pay X life.
Target creature gets +X/+0 until end of turn.

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Blightsteel Colossus

Trample, infect, indestructible
If Blightsteel Colossus would be put into a graveyard from anywhere, reveal Blightsteel Colossus and shuffle it into its owner's library instead.

Dark Confidant

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Cabal Ritual

Add {B}{B}{B}.
Threshold — Add {B}{B}{B}{B}{B} instead if seven or more cards are in your graveyard.

Nightmare Lash

Equipped creature gets +1/+1 for each Swamp you control.
Equip—Pay 3 life. (Pay 3 life: Attach to target creature you control. Equip only as a sorcery. This card enters unattached and stays on the battlefield if the creature leaves.)

Sol Ring

Lashwrithe

Living weapon (When this Equipment enters, create a 0/0 black Phyrexian Germ creature token, then attach this to it.)
Equipped creature gets +1/+1 for each Swamp you control.
Equip {B/P}{B/P} ({B/P} can be paid with either {B} or 2 life.)

Opposition Agent

Flash
You control your opponents while they're searching their libraries.
While an opponent is searching their library, they exile each card they find. You may play those cards for as long as they remain exiled, and you may spend mana as though it were mana of any color to cast them.

Phyresis Outbreak

Each opponent gets a poison counter. Then each creature your opponents control gets -1/-1 until end of turn for each poison counter its controller has.

Entomb

Search your library for a card, put that card into your graveyard, then shuffle.

Hand of the Praetors

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Other creatures you control with infect get +1/+1.
Whenever you cast a creature spell with infect, target player gets a poison counter.

Insatiable Avarice

Spree (Choose one or more additional costs.)
+ {2} — Search your library for a card, then shuffle and put that card on top.
+ {B}{B} — Target player draws three cards and loses 3 life.

Vraska, Betrayal's Sting

Compleated ({B/P} can be paid with {B} or 2 life. If life was paid, this planeswalker enters with two fewer loyalty counters.)
0: You draw a card and you lose 1 life. Proliferate.
−2: Target creature becomes a Treasure artifact with "{T}, Sacrifice this artifact: Add one mana of any color" and loses all other card types and abilities.
−9: If target player has fewer than nine poison counters, they get a number of poison counters equal to the difference.

Dark Ritual

Bilious Skulldweller

Deathtouch
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)