Leyline of Punishment

If Leyline of Punishment is in your opening hand, you may begin the game with it on the battlefield.
Players can't gain life.
Damage can't be prevented.

Leyline of Mutation

If Leyline of Mutation is in your opening hand, you may begin the game with it on the battlefield.
You may pay {W}{U}{B}{R}{G} rather than pay the mana cost for spells you cast.

Leyline Binding

Flash
Domain — This spell costs {1} less to cast for each basic land type among lands you control.
When Leyline Binding enters, exile target nonland permanent an opponent controls until Leyline Binding leaves the battlefield.

Leyline of the Meek

If Leyline of the Meek is in your opening hand, you may begin the game with it on the battlefield.
Creature tokens get +1/+1.

Leyline of Vitality

If Leyline of Vitality is in your opening hand, you may begin the game with it on the battlefield.
Creatures you control get +0/+1.
Whenever a creature you control enters, you may gain 1 life.

Leyline of the Guildpact

If Leyline of the Guildpact is in your opening hand, you may begin the game with it on the battlefield.
Each nonland permanent you control is all colors.
Lands you control are every basic land type in addition to their other types.

Leyline of Hope

If Leyline of Hope is in your opening hand, you may begin the game with it on the battlefield.
If you would gain life, you gain that much life plus 1 instead.
As long as you have at least 7 life more than your starting life total, creatures you control get +2/+2.

Leyline of Singularity

If Leyline of Singularity is in your opening hand, you may begin the game with it on the battlefield.
All nonland permanents are legendary.

Leyline of Anticipation

If Leyline of Anticipation is in your opening hand, you may begin the game with it on the battlefield.
You may cast spells as though they had flash.

Leyline of the Void

If Leyline of the Void is in your opening hand, you may begin the game with it on the battlefield.
If a card would be put into an opponent's graveyard from anywhere, exile it instead.

Leyline of Transformation

If Leyline of Transformation is in your opening hand, you may begin the game with it on the battlefield.
As Leyline of Transformation enters, choose a creature type.
Creatures you control are the chosen type in addition to their other types. The same is true for creature spells you control and creature cards you own that aren't on the battlefield.

Go-Shintai of Life's Origin

{W}{U}{B}{R}{G}, {T}: Return target enchantment card from your graveyard to the battlefield.
Whenever Go-Shintai of Life's Origin or another nontoken Shrine you control enters, create a 1/1 colorless Shrine enchantment creature token.

Leyline of Lightning

If Leyline of Lightning is in your opening hand, you may begin the game with it on the battlefield.
Whenever you cast a spell, you may pay {1}. If you do, Leyline of Lightning deals 1 damage to target player or planeswalker.

Leyline Axe

If this card is in your opening hand, you may begin the game with it on the battlefield.
Equipped creature gets +1/+1 and has double strike and trample.
Equip {3} ({3}: Attach to target creature you control. Equip only as a sorcery.)

Leyline of Sanctity

If Leyline of Sanctity is in your opening hand, you may begin the game with it on the battlefield.
You have hexproof. (You can't be the target of spells or abilities your opponents control.)

Leyline of Abundance

If Leyline of Abundance is in your opening hand, you may begin the game with it on the battlefield.
Whenever you tap a creature for mana, add an additional {G}.
{6}{G}{G}: Put a +1/+1 counter on each creature you control.

Leyline of Combustion

If Leyline of Combustion is in your opening hand, you may begin the game with it on the battlefield.
Whenever you and/or at least one permanent you control becomes the target of a spell or ability an opponent controls, Leyline of Combustion deals 2 damage to that player.

Leyline of Resonance

If Leyline of Resonance is in your opening hand, you may begin the game with it on the battlefield.
Whenever you cast an instant or sorcery spell that targets only a single creature you control, copy that spell. You may choose new targets for the copy.

Leyline of Lifeforce

If Leyline of Lifeforce is in your opening hand, you may begin the game with it on the battlefield.
Creature spells can't be countered.