Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Ghostly Prison

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Negate

Soul Warden

Whenever another creature enters, you gain 1 life.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Sea of Clouds

Sea of Clouds enters tapped unless you have two or more opponents.
{T}: Add {W} or {U}.

Elenda, the Dusk Rose

Lifelink
Whenever another creature dies, put a +1/+1 counter on Elenda, the Dusk Rose.
When Elenda dies, create X 1/1 white Vampire creature tokens with lifelink, where X is Elenda's power.

Angel of Destiny

Flying, double strike
Whenever a creature you control deals combat damage to a player, you and that player each gain that much life.
At the beginning of your end step, if you have at least 15 life more than your starting life total, each player Angel of Destiny attacked this turn loses the game.

Drowned Catacomb

Drowned Catacomb enters tapped unless you control an Island or a Swamp.
{T}: Add {U} or {B}.

Elenda and Azor

Flying, ward {2}
Whenever Elenda and Azor attacks, you may pay {X}{W}{U}{B}. If you do, draw X cards.
At the beginning of each end step, you may pay 4 life. If you do, create a number of 1/1 black Vampire Knight creature tokens with lifelink equal to the number of cards you've drawn this turn.

Deserted Beach

Deserted Beach enters tapped unless you control two or more other lands.
{T}: Add {W} or {U}.

Plains

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. Talisman of Dominance deals 1 damage to you.

Black Market Connections

At the beginning of your first main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It has every creature type.)

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Temple of Silence

Temple of Silence enters tapped.
When Temple of Silence enters, scry 1.
{T}: Add {W} or {B}.

Raffine's Tower

({T}: Add {W}, {U}, or {B}.)
Raffine's Tower enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, Serra Ascendant gets +5/+5 and has flying.

Lunar Convocation

At the beginning of your end step, if you gained life this turn, each opponent loses 1 life.
At the beginning of your end step, if you gained and lost life this turn, create a 1/1 black Bat creature token with flying.
{1}{B}, Pay 2 life: Draw a card.

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Sol Ring

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.

Arcane Sanctum

Arcane Sanctum enters tapped.
{T}: Add {W}, {U}, or {B}.

Dimir Signet

Speaker of the Heavens

Vigilance, lifelink
{T}: Create a 4/4 white Angel creature token with flying. Activate only if you have at least 7 life more than your starting life total and only as a sorcery.

Shroudstomper

Deathtouch
Whenever Shroudstomper enters or attacks, each opponent loses 2 life. You gain 2 life and draw a card.

Enduring Tenacity

Whenever you gain life, target opponent loses that much life.
When Enduring Tenacity dies, if it was a creature, return it to the battlefield under its owner's control. It's an enchantment. (It's not a creature.)

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Felidar Sovereign

Vigilance, lifelink
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Hallowed Fountain

({T}: Add {W} or {U}.)
As Hallowed Fountain enters, you may pay 2 life. If you don't, it enters tapped.

Prairie Stream

({T}: Add {W} or {U}.)
Prairie Stream enters tapped unless you control two or more basic lands.

Starscape Cleric

Offspring {2}{B} (You may pay an additional {2}{B} as you cast this spell. If you do, when this creature enters, create a 1/1 token copy of it.)
Flying
This creature can't block.
Whenever you gain life, each opponent loses 1 life.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Elenda's Hierophant

Flying
Whenever you gain life, put a +1/+1 counter on Elenda's Hierophant.
When Elenda's Hierophant dies, create X 1/1 white Vampire creature tokens with lifelink, where X is its power.

Esper Sentinel

Whenever an opponent casts their first noncreature spell each turn, draw a card unless that player pays {X}, where X is Esper Sentinel's power.

Void Rend

This spell can't be countered.
Destroy target nonland permanent.

Azorius Signet

Essence Channeler

As long as you've lost life this turn, Essence Channeler has flying and vigilance.
Whenever you gain life, put a +1/+1 counter on Essence Channeler.
When Essence Channeler dies, put its counters on target creature you control.

Talisman of Progress

{T}: Add {C}.
{T}: Add {W} or {U}. Talisman of Progress deals 1 damage to you.

Orzhov Signet

Shipwreck Marsh

Shipwreck Marsh enters tapped unless you control two or more other lands.
{T}: Add {U} or {B}.

Propaganda

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Despark

Exile target permanent with mana value 4 or greater.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Isolated Chapel

Isolated Chapel enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Reliquary Tower

Command Tower

Oloro, Ageless Ascetic

At the beginning of your upkeep, you gain 2 life.
Whenever you gain life, you may pay {1}. If you do, draw a card and each opponent loses 1 life.
At the beginning of your upkeep, if Oloro, Ageless Ascetic is in the command zone, you gain 2 life.

Sunken Hollow

({T}: Add {U} or {B}.)
Sunken Hollow enters tapped unless you control two or more basic lands.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Will, Scion of Peace

Vigilance
{T}: Spells you cast this turn that are white and/or blue cost {X} less to cast, where X is the amount of life you gained this turn. Activate only as a sorcery.

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Marina Vendrell's Grimoire

When Marina Vendrell's Grimoire enters, if you cast it, draw five cards.
You have no maximum hand size and don't lose the game for having 0 or less life.
Whenever you gain life, draw that many cards.
Whenever you lose life, discard that many cards. Then if you have no cards in hand, you lose the game.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters, you may pay 2 life. If you don't, it enters tapped.

Floodfarm Verge

{T}: Add {W}.
{T}: Add {U}. Activate only if you control a Plains or an Island.

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter tapped.

Watery Grave

({T}: Add {U} or {B}.)
As Watery Grave enters, you may pay 2 life. If you don't, it enters tapped.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Mana Drain

Counter target spell. At the beginning of your next main phase, add an amount of {C} equal to that spell's mana value.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Glacial Fortress

Glacial Fortress enters tapped unless you control a Plains or an Island.
{T}: Add {W} or {U}.

Vault of Champions

Vault of Champions enters tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Karlov of the Ghost Council

Whenever you gain life, put two +1/+1 counters on Karlov of the Ghost Council.
{W}{B}, Remove six +1/+1 counters from Karlov of the Ghost Council: Exile target creature.

Voice of the Blessed

Whenever you gain life, put a +1/+1 counter on Voice of the Blessed.
As long as Voice of the Blessed has four or more +1/+1 counters on it, it has flying and vigilance.
As long as Voice of the Blessed has ten or more +1/+1 counters on it, it has indestructible.

Dovin's Veto

This spell can't be countered.
Counter target noncreature spell.

Enlightened Tutor

Search your library for an artifact or enchantment card, reveal it, then shuffle and put that card on top.

Orzhov Basilica

Orzhov Basilica enters tapped.
When Orzhov Basilica enters, return a land you control to its owner's hand.
{T}: Add {W}{B}.

Cyclonic Rift

Return target nonland permanent you don't control to its owner's hand.
Overload {6}{U} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Morphic Pool

Morphic Pool enters tapped unless you have two or more opponents.
{T}: Add {U} or {B}.

Swamp

Island

Queza, Augur of Agonies

Whenever you draw a card, target opponent loses 1 life and you gain 1 life.

Counterspell

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Amalia Benavides Aguirre

Ward—Pay 3 life.
Whenever you gain life, Amalia Benavides Aguirre explores. Then destroy all other creatures if its power is exactly 20. (To have this creature explore, reveal the top card of your library. Put that card into your hand if it's a land. Otherwise, put a +1/+1 counter on this creature, then put the card back or put it into your graveyard.)