Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Shattered Angel

Flying
Whenever a land an opponent controls enters, you may gain 3 life.

Ajani's Pridemate

Whenever you gain life, put a +1/+1 counter on this creature.

Dega Sanctuary

At the beginning of your upkeep, if you control a black or red permanent, you gain 2 life. If you control a black permanent and a red permanent, you gain 4 life instead.

Sun Titan

Vigilance
Whenever Sun Titan enters or attacks, you may return target permanent card with mana value 3 or less from your graveyard to the battlefield.

Erebos, God of the Dead

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Your opponents can't gain life.
{1}{B}, Pay 2 life: Draw a card.

Spirit Loop

Enchant creature you control
Whenever enchanted creature deals damage, you gain that much life.
When Spirit Loop is put into a graveyard from the battlefield, return Spirit Loop to its owner's hand.

Eternity Vessel

Eternity Vessel enters with X charge counters on it, where X is your life total.
Landfall — Whenever a land you control enters, you may have your life total become the number of charge counters on Eternity Vessel.

Rakdos Signet

Celestial Mantle

Enchant creature
Enchanted creature gets +3/+3.
Whenever enchanted creature deals combat damage to a player, double its controller's life total.

Boros Signet

Dark Suspicions

At the beginning of each opponent's upkeep, that player loses X life, where X is the number of cards in that player's hand minus the number of cards in your hand.

Hatred

As an additional cost to cast this spell, pay X life.
Target creature gets +X/+0 until end of turn.

Ayli, Eternal Pilgrim

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
{1}, Sacrifice another creature: You gain life equal to the sacrificed creature's toughness.
{1}{W}{B}, Sacrifice another creature: Exile target nonland permanent. Activate only if you have at least 10 life more than your starting life total.

Price of Progress

Price of Progress deals damage to each player equal to twice the number of nonbasic lands that player controls.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Proper Burial

Whenever a creature you control dies, you gain life equal to that creature's toughness.

Curse of Opulence

Enchant player
Whenever enchanted player is attacked, create a Gold token. Each opponent attacking that player does the same. (A Gold token is an artifact with "Sacrifice this artifact: Add one mana of any color.")

Blood Tribute

Kicker—Tap an untapped Vampire you control. (You may tap a Vampire you control in addition to any other costs as you cast this spell.)
Target opponent loses half their life, rounded up. If this spell was kicked, you gain life equal to the life lost this way.

Celestial Force

At the beginning of each upkeep, you gain 3 life.

Faith's Fetters

Enchant permanent
When Faith's Fetters enters, you gain 4 life.
Enchanted permanent can't attack or block, and its activated abilities can't be activated unless they're mana abilities.

False Cure

Until end of turn, whenever a player gains life, that player loses 2 life for each 1 life they gained.

Archangel of Thune

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
Whenever you gain life, put a +1/+1 counter on each creature you control.

Reverse the Sands

Redistribute any number of players' life totals. (Each of those players gets one life total back.)

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Aura of Silence

Artifact and enchantment spells your opponents cast cost {2} more to cast.
Sacrifice Aura of Silence: Destroy target artifact or enchantment.

Polluted Bonds

Whenever a land an opponent controls enters, that player loses 2 life and you gain 2 life.

Cradle of Vitality

Whenever you gain life, you may pay {1}{W}. If you do, put a +1/+1 counter on target creature for each 1 life you gained.

Blessing of Leeches

Flash
Enchant creature
At the beginning of your upkeep, you lose 1 life.
{0}: Regenerate enchanted creature.

Sol Ring

Orzhov Signet

Children of Korlis

Sacrifice Children of Korlis: You gain life equal to the life you've lost this turn. (Damage causes loss of life.)

Angelic Chorus

Whenever a creature you control enters, you gain life equal to its toughness.

Tainted Sigil

{T}, Sacrifice Tainted Sigil: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Crested Sunmare

Other Horses you control have indestructible.
At the beginning of each end step, if you gained life this turn, create a 5/5 white Horse creature token.

Treasonous Ogre

Dethrone (Whenever this creature attacks the player with the most life or tied for most life, put a +1/+1 counter on it.)
Pay 3 life: Add {R}.

Agent of Masks

At the beginning of your upkeep, each opponent loses 1 life. You gain life equal to the life lost this way.

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Searing Meditation

Whenever you gain life, you may pay {2}. If you do, Searing Meditation deals 2 damage to any target.

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Thud

As an additional cost to cast this spell, sacrifice a creature.
Thud deals damage equal to the sacrificed creature's power to any target.

Batwing Brume

Prevent all combat damage that would be dealt this turn if {W} was spent to cast this spell. Each player loses 1 life for each attacking creature they control if {B} was spent to cast this spell. (Do both if {W}{B} was spent.)

Murderous Betrayal

{B}{B}, Pay half your life, rounded up: Destroy target nonblack creature. It can't be regenerated.

Felidar Sovereign

Vigilance (Attacking doesn't cause this creature to tap.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your upkeep, if you have 40 or more life, you win the game.

True Conviction

Creatures you control have double strike and lifelink.

Dross Harvester

Protection from white
At the beginning of your end step, you lose 4 life.
Whenever a creature dies, you gain 2 life.

Vona, Butcher of Magan

Vigilance, lifelink
{T}, Pay 7 life: Destroy target nonland permanent. Activate only during your turn.

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, Serra Ascendant gets +5/+5 and has flying.

Dawn of Hope

Whenever you gain life, you may pay {2}. If you do, draw a card.
{3}{W}: Create a 1/1 white Soldier creature token with lifelink.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with Tree of Perdition's toughness.

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Elenda, the Dusk Rose

Lifelink
Whenever another creature dies, put a +1/+1 counter on Elenda, the Dusk Rose.
When Elenda dies, create X 1/1 white Vampire creature tokens with lifelink, where X is Elenda's power.

Font of Agonies

Whenever you pay life, put that many blood counters on Font of Agonies.
{1}{B}, Remove four blood counters from Font of Agonies: Destroy target creature.

Minion of the Wastes

Trample
As Minion of the Wastes enters, pay any amount of life.
Minion of the Wastes's power and toughness are each equal to the life paid as it entered.

Ajani's Welcome

Whenever a creature you control enters, you gain 1 life.

Solemn Simulacrum

When this creature enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When this creature dies, you may draw a card.

Karlov of the Ghost Council

Whenever you gain life, put two +1/+1 counters on Karlov of the Ghost Council.
{W}{B}, Remove six +1/+1 counters from Karlov of the Ghost Council: Exile target creature.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter tapped.

Soul Warden

Whenever another creature enters, you gain 1 life.

Near-Death Experience

At the beginning of your upkeep, if you have exactly 1 life, you win the game.

Tainted Remedy

If an opponent would gain life, that player loses that much life instead.

Angelic Accord

At the beginning of each end step, if you gained 4 or more life this turn, create a 4/4 white Angel creature token with flying.

First Response

At the beginning of each upkeep, if you lost life last turn, create a 1/1 white Soldier creature token.

Baleful Force

At the beginning of each upkeep, you draw a card and you lose 1 life.

Miren, the Moaning Well

{T}: Add {C}.
{3}, {T}, Sacrifice a creature: You gain life equal to the sacrificed creature's toughness.

Bruse Tarl, Boorish Herder

Whenever Bruse Tarl, Boorish Herder enters or attacks, target creature you control gains double strike and lifelink until end of turn.
Partner (You can have two commanders if both have partner.)

Dragon Breath

Enchant creature
Enchanted creature has haste.
{R}: Enchanted creature gets +1/+0 until end of turn.
When a creature with mana value 6 or greater enters, you may return Dragon Breath from your graveyard to the battlefield attached to that creature.

Vault of the Archangel

{T}: Add {C}.
{2}{W}{B}, {T}: Creatures you control gain deathtouch and lifelink until end of turn.

Selenia, Dark Angel

Flying
Pay 2 life: Return Selenia, Dark Angel to its owner's hand.

Phyrexian Processor

As Phyrexian Processor enters, pay any amount of life.
{4}, {T}: Create an X/X black Phyrexian Minion creature token, where X is the life paid as Phyrexian Processor entered.

Test of Endurance

At the beginning of your upkeep, if you have 50 or more life, you win the game.

Storm Herd

Create X 1/1 white Pegasus creature tokens with flying, where X is your life total.

Fire Covenant

As an additional cost to cast this spell, pay X life.
Fire Covenant deals X damage divided as you choose among any number of target creatures.

Land Tax

At the beginning of your upkeep, if an opponent controls more lands than you, you may search your library for up to three basic land cards, reveal them, put them into your hand, then shuffle.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Firesong and Sunspeaker

Red instant and sorcery spells you control have lifelink.
Whenever a white instant or sorcery spell causes you to gain life, Firesong and Sunspeaker deals 3 damage to target creature or player.

Blessed Reversal

You gain 3 life for each creature attacking you.

Brightflame

Radiance — Brightflame deals X damage to target creature and each other creature that shares a color with it. You gain life equal to the damage dealt this way.

Suture Priest

Whenever another creature you control enters, you may gain 1 life.
Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Dread Defiler

Devoid (This card has no color.)
{3}{C}, Exile a creature card from your graveyard: Target opponent loses life equal to the exiled card's power. ({C} represents colorless mana.)

Feast on the Fallen

At the beginning of each upkeep, if an opponent lost life last turn, put a +1/+1 counter on target creature you control.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Resolute Archangel

Flying
When Resolute Archangel enters, if your life total is less than your starting life total, it becomes equal to your starting life total.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Auriok Champion

Protection from black and from red
Whenever another creature enters, you may gain 1 life.

Loxodon Warhammer

Equipped creature gets +3/+0 and has trample and lifelink.
Equip {3}

Balefire Liege

Other red creatures you control get +1/+1.
Other white creatures you control get +1/+1.
Whenever you cast a red spell, Balefire Liege deals 3 damage to target player or planeswalker.
Whenever you cast a white spell, you gain 3 life.

Sunbond

Enchant creature
Enchanted creature has "Whenever you gain life, put that many +1/+1 counters on this creature."

Divinity of Pride

Flying, lifelink
Divinity of Pride gets +4/+4 as long as you have 25 or more life.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Evra, Halcyon Witness

Lifelink
{4}: Exchange your life total with Evra, Halcyon Witness's power.

Lurking Evil

Pay half your life, rounded up: Lurking Evil becomes a 4/4 Phyrexian Horror creature with flying.

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Acidic Soil

Acidic Soil deals damage to each player equal to the number of lands they control.

Kokusho, the Evening Star

Flying
When Kokusho, the Evening Star dies, each opponent loses 5 life. You gain life equal to the life lost this way.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Licia, Sanguine Tribune

This spell costs {1} less to cast for each 1 life you gained this turn.
First strike, lifelink
Pay 5 life: Put three +1/+1 counters on Licia, Sanguine Tribune. Activate only during your turn and only once each turn.

Boon Reflection

If you would gain life, you gain twice that much life instead.