Ulamog, the Defiler

When you cast this spell, target opponent exiles the top half of their library, rounded up.
Ward—Sacrifice two permanents.
Ulamog, the Defiler enters with a number of +1/+1 counters on it equal to the greatest mana value among cards in exile.
Ulamog has annihilator X, where X is the number of +1/+1 counters on it.

Ulamog, the Infinite Gyre

When you cast this spell, destroy target permanent.
Indestructible
Annihilator 4 (Whenever this creature attacks, defending player sacrifices four permanents.)
When Ulamog, the Infinite Gyre is put into a graveyard from anywhere, its owner shuffles their graveyard into their library.

Ulamog's Crusher

Annihilator 2 (Whenever this creature attacks, defending player sacrifices two permanents.)
Ulamog's Crusher attacks each combat if able.

Spawnsire of Ulamog

Annihilator 1 (Whenever this creature attacks, defending player sacrifices a permanent.)
{4}: Create two 0/1 colorless Eldrazi Spawn creature tokens. They have "Sacrifice this creature: Add {C}."
{20}: Cast any number of Eldrazi spells from among cards you own outside the game without paying their mana costs.

Hand of Emrakul

You may sacrifice four Eldrazi Spawn rather than pay this spell's mana cost.
Annihilator 1 (Whenever this creature attacks, defending player sacrifices a permanent.)

Idol of False Gods

{1}{C}, {T}: Create a 0/1 colorless Eldrazi Spawn creature token with "Sacrifice this creature: Add {C}."
Whenever another Eldrazi you control dies, put a +1/+1 counter on Idol of False Gods.
As long as Idol of False Gods has eight or more +1/+1 counters on it, it's a 0/0 creature in addition to its other types and it has annihilator 2.

It That Betrays

Annihilator 2 (Whenever this creature attacks, defending player sacrifices two permanents.)
Whenever an opponent sacrifices a nontoken permanent, put that card onto the battlefield under your control.

Eldrazi Ravager

Annihilator 1 (Whenever this creature attacks, defending player sacrifices a permanent.)
Sacrifice two Eldrazi: Return Eldrazi Ravager from your graveyard to your hand.
Cycling {2} ({2}, Discard this card: Draw a card.)

Eldrazi Conscription

Enchant creature
Enchanted creature gets +10/+10 and has trample and annihilator 2. (Whenever it attacks, defending player sacrifices two permanents.)

Artisan of Kozilek

When you cast this spell, you may return target creature card from your graveyard to the battlefield.
Annihilator 2 (Whenever this creature attacks, defending player sacrifices two permanents.)

Flayer of Loyalties

When you cast this spell, gain control of target creature until end of turn. Untap that creature. Until end of turn, it has base power and toughness 10/10 and gains trample, annihilator 2, and haste.
Annihilator 2 (Whenever this creature attacks, defending player sacrifices two permanents.)
Trample

Pathrazer of Ulamog

Annihilator 3 (Whenever this creature attacks, defending player sacrifices three permanents.)
Pathrazer of Ulamog can't be blocked except by three or more creatures.

Nazgûl Battle-Mace

Equipped creature has menace, deathtouch, annihilator 1, and "Whenever an opponent sacrifices a nontoken permanent, put that card onto the battlefield under your control unless that player pays 3 life." (Whenever a creature with annihilator 1 attacks, defending player sacrifices a permanent.)
Equip {3}

Breaker of Creation

When you cast this spell, you gain 1 life for each colorless permanent you control.
Hexproof from each color
Annihilator 2 (Whenever this creature attacks, defending player sacrifices two permanents.)

Kozilek, Butcher of Truth

When you cast this spell, draw four cards.
Annihilator 4 (Whenever this creature attacks, defending player sacrifices four permanents.)
When Kozilek, Butcher of Truth is put into a graveyard from anywhere, its owner shuffles their graveyard into their library.