Dalek Drone

Flying, menace
Exterminate! — When Dalek Drone enters, destroy target creature an opponent controls. That player loses 3 life.

Bitter Downfall

This spell costs {3} less to cast if it targets a creature that was dealt damage this turn.
Destroy target creature. Its controller loses 2 life.

Sol Ring

Attrition

{B}, Sacrifice a creature: Destroy target nonblack creature.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Acidic Slime

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
When Acidic Slime enters, destroy target artifact, enchantment, or land.

Atraxa's Fall

Destroy target artifact, battle, enchantment, or creature with flying.

Golgari Signet

Assassin's Trophy

Destroy target permanent an opponent controls. Its controller may search their library for a basic land card, put it onto the battlefield, then shuffle.

Abrupt Decay

This spell can't be countered.
Destroy target nonland permanent with mana value 3 or less.

Alpha Deathclaw

Menace, trample
When Alpha Deathclaw enters or becomes monstrous, destroy target permanent.
{5}{B}{G}: Monstrosity 4. (If this creature isn't monstrous, put four +1/+1 counters on it and it becomes monstrous.)

Casualties of War

Choose one or more —
• Destroy target artifact.
• Destroy target creature.
• Destroy target enchantment.
• Destroy target land.
• Destroy target planeswalker.

Assassinate

Avatar of Woe

If there are ten or more creature cards total in all graveyards, this spell costs {6} less to cast.
Fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
{T}: Destroy target creature. It can't be regenerated.

Aberrant

Ravenous (This creature enters with X +1/+1 counters on it. If X is 5 or more, draw a card when it enters.)
Trample
Heavy Power Hammer — Whenever Aberrant deals combat damage to a player, destroy target artifact or enchantment that player controls.

Chain of Acid

Destroy target noncreature permanent. Then that permanent's controller may copy this spell and may choose a new target for that copy.

Bounty Hunter

{T}: Put a bounty counter on target nonblack creature.
{T}: Destroy target creature with a bounty counter on it.

Cast Down

Bake into a Pie

Destroy target creature. Create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this token: You gain 3 life.")

Appetite for the Unnatural

Destroy target artifact or enchantment. You gain 2 life.

Chevill, Bane of Monsters

Deathtouch
At the beginning of your upkeep, if your opponents control no permanents with bounty counters on them, put a bounty counter on target creature or planeswalker an opponent controls.
Whenever a permanent an opponent controls with a bounty counter on it dies, you gain 3 life and draw a card.

Bounty Board

{T}: Add one mana of any color.
{1}, {T}: Put a bounty counter on target creature. Activate only as a sorcery.
Whenever a creature with a bounty counter on it dies, each of its controller's opponents draws a card and gains 2 life.

Altar of Shadows

At the beginning of your first main phase, add {B} for each charge counter on Altar of Shadows.
{7}, {T}: Destroy target creature. Then put a charge counter on Altar of Shadows.

Argentum Armor

Equipped creature gets +6/+6.
Whenever equipped creature attacks, destroy target permanent.
Equip {6}

Termination Facilitator

{T}: Put a bounty counter on target creature or planeswalker. Activate only as a sorcery.
Whenever a creature or planeswalker an opponent controls with a bounty counter on it is dealt damage, destroy it.

Cavalier of Night

Lifelink
When Cavalier of Night enters, you may sacrifice another creature. When you do, destroy target creature an opponent controls.
When Cavalier of Night dies, return target creature card with mana value 3 or less from your graveyard to the battlefield.