Exterminatus

Nonland permanents your opponents control lose indestructible until end of turn.
Destroy all nonland permanents.

Creepy Doll

Indestructible
Whenever Creepy Doll deals combat damage to a creature, flip a coin. If you win the flip, destroy that creature.

Nevinyrral, Urborg Tyrant

Hexproof from artifacts, creatures, and enchantments
When Nevinyrral, Urborg Tyrant enters, create a tapped 2/2 black Zombie creature token for each creature that died this turn.
When Nevinyrral dies, you may pay {1}. When you do, destroy all artifacts, creatures, and enchantments.

Tyrite Sanctum

{T}: Add {C}.
{2}, {T}: Target legendary creature becomes a God in addition to its other types. Put a +1/+1 counter on it.
{4}, {T}, Sacrifice Tyrite Sanctum: Put an indestructible counter on target God.

Seraph of the Suns

Flying
Indestructible (Damage and effects that say "destroy" don't destroy this creature. If its toughness is 0 or less, it's still put into its owner's graveyard.)

Thassa, God of the Sea

Indestructible
As long as your devotion to blue is less than five, Thassa isn't a creature. (Each {U} in the mana costs of permanents you control counts toward your devotion to blue.)
At the beginning of your upkeep, scry 1.
{1}{U}: Target creature you control can't be blocked this turn.

Vronos, Masked Inquisitor

+1: Up to two other target planeswalkers you control phase out at the beginning of the next end step. (Treat them and anything attached to them as though they don't exist until your next turn.)
−2: For each opponent, return up to one target nonland permanent that player controls to its owner's hand.
−7: Target artifact you control becomes a 9/9 Construct artifact creature and gains vigilance, indestructible, and "This creature can't be blocked."

Skyclave Relic

Kicker {3}
Indestructible
When Skyclave Relic enters, if it was kicked, create two tapped tokens that are copies of Skyclave Relic.
{T}: Add one mana of any color.

Necron Monolith

Flying, indestructible
Eternity Gate — Whenever Necron Monolith attacks, mill three cards. For each creature card milled this way, create a 2/2 black Necron Warrior artifact creature token.
Crew 4 (Tap any number of creatures you control with total power 4 or more: This Vehicle becomes an artifact creature until end of turn.)

Colossus of Akros

Defender, indestructible
{10}: Monstrosity 10. (If this creature isn't monstrous, put ten +1/+1 counters on it and it becomes monstrous.)
As long as Colossus of Akros is monstrous, it has trample and can attack as though it didn't have defender.

Manor Gargoyle

Defender
Manor Gargoyle has indestructible as long as it has defender.
{1}: Until end of turn, Manor Gargoyle loses defender and gains flying.

Stuffy Doll

Indestructible
As Stuffy Doll enters, choose a player.
Whenever Stuffy Doll is dealt damage, it deals that much damage to the chosen player.
{T}: Stuffy Doll deals 1 damage to itself.

Shay Cormac

{1}: Permanents your opponents control lose hexproof, indestructible, protection, shroud, and ward until end of turn.
Whenever a creature an opponent controls becomes the target of a spell or ability you control, put a bounty counter on that creature.
Whenever a creature with a bounty counter on it dies, put two +1/+1 counters on Shay Cormac.

Vashta Nerada

Indestructible
Shadow (This creature can block or be blocked by only creatures with shadow.)
Morbid — At the beginning of each end step, if a creature died this turn, put a +1/+1 counter on Vashta Nerada.

Myojin of Grim Betrayal

Myojin of Grim Betrayal enters with an indestructible counter on it if you cast it from your hand.
Remove an indestructible counter from Myojin of Grim Betrayal: Put onto the battlefield under your control all creature cards in all graveyards that were put there from anywhere this turn.

Transcendent Master

Level up {1} ({1}: Put a level counter on this. Level up only as a sorcery.)
LEVEL 6-11
6/6
Lifelink
LEVEL 12+
9/9
Lifelink, indestructible

Fated Return

Put target creature card from a graveyard onto the battlefield under your control. It gains indestructible. If it's your turn, scry 2.

Bontu the Glorified

Menace, indestructible
Bontu the Glorified can't attack or block unless a creature died under your control this turn.
{1}{B}, Sacrifice another creature: Scry 1. Each opponent loses 1 life and you gain 1 life.

Phylactery Lich

Indestructible
As Phylactery Lich enters, put a phylactery counter on an artifact you control.
When you control no permanents with phylactery counters on them, sacrifice Phylactery Lich.

Kefnet the Mindful

Flying, indestructible
Kefnet the Mindful can't attack or block unless you have seven or more cards in hand.
{3}{U}: Draw a card, then you may return a land you control to its owner's hand.

Daring Fiendbonder

Haste
Daring Fiendbonder attacks each combat if able.
{1}{B}, Exile Daring Fiendbonder from your graveyard: Put an indestructible counter on target creature. Activate only as a sorcery.

Dark Depths

Dark Depths enters with ten ice counters on it.
{3}: Remove an ice counter from Dark Depths.
When Dark Depths has no ice counters on it, sacrifice it. If you do, create Marit Lage, a legendary 20/20 black Avatar creature token with flying and indestructible.

Athreos, Shroud-Veiled

Indestructible
As long as your devotion to white and black is less than seven, Athreos isn't a creature.
At the beginning of your end step, put a coin counter on another target creature.
Whenever a creature with a coin counter on it dies or is put into exile, return that card to the battlefield under your control.

Darksteel Ingot

Indestructible (Effects that say "destroy" don't destroy this artifact.)
{T}: Add one mana of any color.

That Which Was Taken

{4}, {T}: Put a divinity counter on target permanent other than That Which Was Taken.
Each permanent with a divinity counter on it has indestructible.

Darksteel Sentinel

Flash (You may cast this spell any time you could cast an instant.)
Vigilance
Indestructible (Damage and effects that say "destroy" don't destroy this creature. If its toughness is 0 or less, it's still put into its owner's graveyard.)

Heliod, God of the Sun

Indestructible
As long as your devotion to white is less than five, Heliod isn't a creature. (Each {W} in the mana costs of permanents you control counts toward your devotion to white.)
Other creatures you control have vigilance.
{2}{W}{W}: Create a 2/1 white Cleric enchantment creature token.

Nevinyrral's Disk

Nevinyrral's Disk enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Battle at the Helvault

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I, II — For each player, exile up to one target non-Saga, nonland permanent that player controls until Battle at the Helvault leaves the battlefield.
III — Create Avacyn, a legendary 8/8 white Angel creature token with flying, vigilance, and indestructible.

Bleeding Effect

At the beginning of combat on your turn, creatures you control gain flying until end of turn if a creature card in your graveyard has flying. The same is true for first strike, double strike, deathtouch, hexproof, indestructible, lifelink, menace, reach, trample, and vigilance.

Oketra the True

Double strike, indestructible
Oketra the True can't attack or block unless you control at least three other creatures.
{3}{W}: Create a 1/1 white Warrior creature token with vigilance.

Zetalpa, Primal Dawn

Flying, double strike, vigilance, trample, indestructible

Eagle of Deliverance

Flying
When Eagle of Deliverance enters, put an indestructible counter on another target creature you control. Draw a card if that creature's power is 2 or less.

Barbed Servitor

Indestructible
When Barbed Servitor enters, suspect it. (It has menace and can't block.)
Whenever Barbed Servitor deals combat damage to a player, you draw a card and you lose 1 life.
Whenever Barbed Servitor is dealt damage, target opponent loses that much life.