Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Intervention Pact

The next time a source of your choice would deal damage to you this turn, prevent that damage. You gain life equal to the damage prevented this way.
At the beginning of your next upkeep, pay {1}{W}{W}. If you don't, you lose the game.

Hero's Downfall

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Blood Seeker

Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Sorin, Grim Nemesis

+1: Reveal the top card of your library and put that card into your hand. Each opponent loses life equal to its mana value.
−X: Sorin, Grim Nemesis deals X damage to target creature or planeswalker and you gain X life.
−9: Create a number of 1/1 black Vampire Knight creature tokens with lifelink equal to the highest life total among all players.

Syr Konrad, the Grim

Whenever another creature dies, or a creature card is put into a graveyard from anywhere other than the battlefield, or a creature card leaves your graveyard, Syr Konrad, the Grim deals 1 damage to each opponent.
{1}{B}: Each player mills a card. (They each put the top card of their library into their graveyard.)

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Karlov of the Ghost Council

Whenever you gain life, put two +1/+1 counters on Karlov of the Ghost Council.
{W}{B}, Remove six +1/+1 counters from Karlov of the Ghost Council: Exile target creature.

Corpse Knight

Whenever another creature you control enters, each opponent loses 1 life.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Breathe Your Last

Destroy target creature or planeswalker. You gain 1 life for each of its colors.

Vraska's Contempt

Exile target creature or planeswalker. You gain 2 life.

Wrath of God

Destroy all creatures. They can't be regenerated.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Batwing Brume

Prevent all combat damage that would be dealt this turn if {W} was spent to cast this spell. Each player loses 1 life for each attacking creature they control if {B} was spent to cast this spell. (Do both if {W}{B} was spent.)

Swamp

Zulaport Cutthroat

Whenever Zulaport Cutthroat or another creature you control dies, each opponent loses 1 life and you gain 1 life.

Necrologia

Cast this spell only during your end step.
As an additional cost to cast this spell, pay X life.
Draw X cards.

Despark

Exile target permanent with mana value 4 or greater.

Trespasser's Curse

Enchant player
Whenever a creature enchanted player controls enters, that player loses 1 life and you gain 1 life.

Cruel Celebrant

Whenever Cruel Celebrant or another creature or planeswalker you control dies, each opponent loses 1 life and you gain 1 life.

Retreat to Hagra

Landfall — Whenever a land you control enters, choose one —
• Target creature gets +1/+0 and gains deathtouch until end of turn.
• Each opponent loses 1 life and you gain 1 life.

Murder

Soul's Attendant

Whenever another creature enters, you may gain 1 life.

Liesa, Shroud of Dusk

Rather than pay {2} for each previous time you've cast this spell from the command zone this game, pay 2 life that many times.
Flying, lifelink
Whenever a player casts a spell, they lose 2 life.

Angel of Destiny

Flying, double strike
Whenever a creature you control deals combat damage to a player, you and that player each gain that much life.
At the beginning of your end step, if you have at least 15 life more than your starting life total, each player Angel of Destiny attacked this turn loses the game.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Rite of Oblivion

As an additional cost to cast this spell, sacrifice a nonland permanent.
Exile target nonland permanent.
Flashback {2}{W}{B} (You may cast this card from your graveyard for its flashback cost and any additional costs. Then exile it.)

Morgul-Knife Wound

Enchant creature
Enchanted creature gets -3/-0 and has "At the beginning of your upkeep, exile this creature unless you pay 2 life."

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Amalia Benavides Aguirre

Ward—Pay 3 life.
Whenever you gain life, Amalia Benavides Aguirre explores. Then destroy all other creatures if its power is exactly 20. (To have this creature explore, reveal the top card of your library. Put that card into your hand if it's a land. Otherwise, put a +1/+1 counter on this creature, then put the card back or put it into your graveyard.)

Elenda, the Dusk Rose

Lifelink
Whenever another creature dies, put a +1/+1 counter on Elenda, the Dusk Rose.
When Elenda dies, create X 1/1 white Vampire creature tokens with lifelink, where X is Elenda's power.

Killing Wave

For each creature, its controller sacrifices it unless they pay X life.

Tymna the Weaver

Lifelink
At the beginning of each of your postcombat main phases, you may pay X life, where X is the number of opponents that were dealt combat damage this turn. If you do, draw X cards.
Partner (You can have two commanders if both have partner.)

Blood Reckoning

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Utter End

Thrull Parasite

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
{T}, Pay 2 life: Remove a counter from target nonland permanent.

Elas il-Kor, Sadistic Pilgrim

Deathtouch
Whenever another creature you control enters, you gain 1 life.
Whenever another creature you control dies, each opponent loses 1 life.

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Damn

Destroy target creature. A creature destroyed this way can't be regenerated.
Overload {2}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Grasp of Fate

When Grasp of Fate enters, for each opponent, exile up to one target nonland permanent that player controls until Grasp of Fate leaves the battlefield. (Those permanents return under their owners' control.)

Massacre Wurm

When this creature enters, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Temporal Extortion

When you cast this spell, any player may pay half their life, rounded up. If a player does, counter Temporal Extortion.
Take an extra turn after this one.

Hissing Miasma

Whenever a creature attacks you, its controller loses 1 life.

Bond of Agony

As an additional cost to cast this spell, pay X life.
Each other player loses X life.

Athreos, God of Passage

Indestructible
As long as your devotion to white and black is less than seven, Athreos isn't a creature.
Whenever another creature you own dies, return it to your hand unless target opponent pays 3 life.

Legions to Ashes

Exile target nonland permanent an opponent controls and all tokens that player controls with the same name as that permanent.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Meathook Massacre II

When Meathook Massacre II enters, each player sacrifices X creatures of their choice.
Whenever a creature you control dies, you may pay 3 life. If you do, return that card under your control with a finality counter on it.
Whenever a creature an opponent controls dies, they may pay 3 life. If they don't, return that card under your control with a finality counter on it.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Blood Tithe

Each opponent loses 3 life. You gain life equal to the life lost this way.

Plains

Avatar of Woe

If there are ten or more creature cards total in all graveyards, this spell costs {6} less to cast.
Fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
{T}: Destroy target creature. It can't be regenerated.

Phyrexian Processor

As Phyrexian Processor enters, pay any amount of life.
{4}, {T}: Create an X/X black Phyrexian Minion creature token, where X is the life paid as Phyrexian Processor entered.

Marchesa's Decree

When Marchesa's Decree enters, you become the monarch.
Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life.

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, Serra Ascendant gets +5/+5 and has flying.

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.

Mask of Griselbrand

Equipped creature has flying and lifelink.
Whenever equipped creature dies, you may pay X life, where X is its power. If you do, draw X cards.
Equip {3}

Ravos, Soultender

Flying
Other creatures you control get +1/+1.
At the beginning of your upkeep, you may return target creature card from your graveyard to your hand.
Partner (You can have two commanders if both have partner.)

Damnation

Last Caress

Target player loses 1 life and you gain 1 life.
Draw a card.

Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Suspended Sentence

Destroy target creature an opponent controls. That player loses 3 life. Exile Suspended Sentence with three time counters on it.
Suspend 3—{1}{B} (Rather than cast this card from your hand, you may pay {1}{B} and exile it with three time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)

Cauldron Familiar

When Cauldron Familiar enters, each opponent loses 1 life and you gain 1 life.
Sacrifice a Food: Return Cauldron Familiar from your graveyard to the battlefield.

Access Maze

Once during each of your turns, you may cast a spell from your hand by paying life equal to its mana value rather than paying its mana cost.
(You may cast either half. That door unlocks on the battlefield. As a sorcery, you may pay the mana cost of a locked door to unlock it.)

Cramped Vents

When you unlock this door, this Room deals 6 damage to target creature an opponent controls. You gain life equal to the excess damage dealt this way.
(You may cast either half. That door unlocks on the battlefield. As a sorcery, you may pay the mana cost of a locked door to unlock it.)

Cramped Vents // Access Maze

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Polluted Bonds

Whenever a land an opponent controls enters, that player loses 2 life and you gain 2 life.

Grave Pact

Whenever a creature you control dies, each other player sacrifices a creature of their choice.

Necrodominance

Skip your draw step.
At the beginning of your end step, you may pay any amount of life. If you do, draw that many cards.
Your maximum hand size is five.
If a card or token would be put into your graveyard from anywhere, exile it instead.

Witch's Oven

{T}, Sacrifice a creature: Create a Food token. If the sacrificed creature's toughness was 4 or greater, create two Food tokens instead. (They're artifacts with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Elenda's Hierophant

Flying
Whenever you gain life, put a +1/+1 counter on Elenda's Hierophant.
When Elenda's Hierophant dies, create X 1/1 white Vampire creature tokens with lifelink, where X is its power.

Soul Warden

Whenever another creature enters, you gain 1 life.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.