Epicure of Blood

Whenever you gain life, each opponent loses 1 life.

The Lord of Pain

Menace
Your opponents can't gain life.
Whenever a player casts their first spell each turn, choose another target player. The Lord of Pain deals damage equal to that spell's mana value to the chosen player.

Mechanized Warfare

If a red or artifact source you control would deal damage to an opponent or a permanent an opponent controls, it deals that much damage plus 1 instead.

Hissing Miasma

Whenever a creature attacks you, its controller loses 1 life.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Bind Spirit

Return target creature card from your graveyard to your hand. (Then exile this card. You may cast the artifact later from exile.)

Ghost Lantern

Whenever a creature you control dies, put a +1/+1 counter on equipped creature.
Equip {1}

Ghost Lantern // Bind Spirit

Twilight Prophet

Flying
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your upkeep, if you have the city's blessing, reveal the top card of your library and put it into your hand. Each opponent loses X life and you gain X life, where X is that card's mana value.

Lightning Bolt

Lightning Bolt deals 3 damage to any target.

Vial Smasher the Fierce

Whenever you cast your first spell each turn, choose an opponent at random. Vial Smasher the Fierce deals damage equal to that spell's mana value to that player or a planeswalker that player controls.
Partner (You can have two commanders if both have partner.)

Razorkin Needlehead

Razorkin Needlehead has first strike during your turn.
Whenever an opponent draws a card, Razorkin Needlehead deals 1 damage to them.

Seeker of Slaanesh

Haste
Allure of Slaanesh — Each opponent must attack with at least one creature each combat if able.

Caustic Bronco

Whenever Caustic Bronco attacks, reveal the top card of your library and put it into your hand. You lose life equal to that card's mana value if Caustic Bronco isn't saddled. Otherwise, each opponent loses that much life.
Saddle 3 (Tap any number of other creatures you control with total power 3 or more: This Mount becomes saddled until end of turn. Saddle only as a sorcery.)

Angrath's Marauders

If a source you control would deal damage to a permanent or player, it deals double that damage to that permanent or player instead.

Gleeful Arsonist

Whenever an opponent casts a noncreature spell, Gleeful Arsonist deals damage equal to its power to that player.
Undying (When this creature dies, if it had no +1/+1 counters on it, return it to the battlefield under its owner's control with a +1/+1 counter on it.)

Fall of Cair Andros

Whenever a creature an opponent controls is dealt excess noncombat damage, amass Orcs X, where X is that excess damage. (Put X +1/+1 counters on an Army you control. It's also an Orc. If you don't control an Army, create a 0/0 black Orc Army creature token first.)
{7}{R}: Fall of Cair Andros deals 7 damage to target creature.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Venomcrawler

Lifelink
Devourer of Souls — Whenever another creature dies, put a +1/+1 counter on Venomcrawler.

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Zoyowa Lava-Tongue

Deathtouch
At the beginning of your end step, if you descended this turn, each opponent may discard a card or sacrifice a permanent. Zoyowa Lava-Tongue deals 3 damage to each opponent who didn't. (You descended if a permanent card was put into your graveyard from anywhere.)

Dalek Drone

Flying, menace
Exterminate! — When Dalek Drone enters, destroy target creature an opponent controls. That player loses 3 life.

Murder

Sol Ring

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Mogis, God of Slaughter

Indestructible
As long as your devotion to black and red is less than seven, Mogis isn't a creature.
At the beginning of each opponent's upkeep, Mogis deals 2 damage to that player unless they sacrifice a creature.

Iridescent Vinelasher

Offspring {2} (You may pay an additional {2} as you cast this spell. If you do, when this creature enters, create a 1/1 token copy of it.)
Landfall — Whenever a land you control enters, this creature deals 1 damage to target opponent.

Citadel of Pain

At the beginning of each player's end step, Citadel of Pain deals X damage to that player, where X is the number of untapped lands they control.

Grievous Wound

Enchant player
Enchanted player can't gain life.
Whenever enchanted player is dealt damage, they lose half their life, rounded up.

Fear of Burning Alive

When Fear of Burning Alive enters, it deals 4 damage to each opponent.
Delirium — Whenever a source you control deals noncombat damage to an opponent, if there are four or more card types among cards in your graveyard, Fear of Burning Alive deals that amount of damage to target creature that player controls.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Pestilence

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pestilence.
{B}: Pestilence deals 1 damage to each creature and each player.

Gimli, Counter of Kills

Trample
Whenever a creature an opponent controls dies, Gimli, Counter of Kills deals 1 damage to that creature's controller.

Great Unclean One

Reverberating Summons — At the beginning of your end step, each opponent loses 2 life. Then for each opponent who has less life than you, create a 1/3 black Demon creature token named Plaguebearer of Nurgle.

Sin Prodder

Menace
At the beginning of your upkeep, reveal the top card of your library. Any opponent may have you put that card into your graveyard. If a player does, Sin Prodder deals damage to that player equal to that card's mana value. Otherwise, put that card into your hand.

Ogre Battlecaster

First strike
Whenever Ogre Battlecaster attacks, you may cast target instant or sorcery card from your graveyard by paying {R}{R} in addition to its other costs. If that spell would be put into a graveyard, exile it instead. When you cast that spell, Ogre Battlecaster gets +X/+0 until end of turn, where X is that spell's mana value.

Syr Konrad, the Grim

Whenever another creature dies, or a creature card is put into a graveyard from anywhere other than the battlefield, or a creature card leaves your graveyard, Syr Konrad, the Grim deals 1 damage to each opponent.
{1}{B}: Each player mills a card. (They each put the top card of their library into their graveyard.)

Brash Taunter

Indestructible
Whenever Brash Taunter is dealt damage, it deals that much damage to target opponent.
{2}{R}, {T}: Brash Taunter fights another target creature.

Maha, Its Feathers Night

Flying, trample
Ward—Discard a card.
Creatures your opponents control have base toughness 1.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Embermaw Hellion

Trample (This creature can deal excess combat damage to the player or planeswalker it's attacking.)
If another red source you control would deal damage to a permanent or player, it deals that much damage plus 1 to that permanent or player instead.

Loyal Subordinate

Menace (This creature can't be blocked except by two or more creatures.)
Lieutenant — At the beginning of combat on your turn, if you control your commander, each opponent loses 3 life.

Blood for the Blood God!

This spell costs {1} less to cast for each creature that died this turn.
Discard your hand, then draw eight cards. Blood for the Blood God! deals 8 damage to each opponent. Exile Blood for the Blood God!

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Plague Drone

Flying
Rot Fly — If an opponent would gain life, that player loses that much life instead.

Kroxa, Titan of Death's Hunger

When Kroxa enters, sacrifice it unless it escaped.
Whenever Kroxa enters or attacks, each opponent discards a card, then each opponent who didn't discard a nonland card this way loses 3 life.
Escape—{B}{B}{R}{R}, Exile five other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)

Dark Ritual

Spiteful Visions

At the beginning of each player's draw step, that player draws an additional card.
Whenever a player draws a card, Spiteful Visions deals 1 damage to that player.

Tangled Colony

Tangled Colony can't block.
When Tangled Colony dies, create X 1/1 black Rat creature tokens with "This creature can't block," where X is the amount of damage dealt to it this turn.

Mutilate

All creatures get -1/-1 until end of turn for each Swamp you control.

Torbran, Thane of Red Fell

If a red source you control would deal damage to an opponent or a permanent an opponent controls, it deals that much damage plus 2 instead.

Defile

Target creature gets -1/-1 until end of turn for each Swamp you control.

Rakdos Signet

Repercussion

Whenever a creature is dealt damage, Repercussion deals that much damage to that creature's controller.

Giggling Skitterspike

Indestructible
Whenever Giggling Skitterspike attacks, blocks, or becomes the target of a spell, it deals damage equal to its power to each opponent.
{5}: Monstrosity 5. (If this creature isn't monstrous, put five +1/+1 counters on it and it becomes monstrous.)

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.

Cemetery Gatekeeper

First strike
When Cemetery Gatekeeper enters, exile a card from a graveyard.
Whenever a player plays a land or casts a spell, if it shares a card type with the exiled card, Cemetery Gatekeeper deals 2 damage to that player.

Vislor Turlough

Deal with the Black Guardian — When Vislor Turlough enters, you may have an opponent gain control of it. If you do, it's goaded for as long as they control it.
At the beginning of your end step, draw a card, then you lose life equal to the number of cards in your hand.
Doctor's companion (You can have two commanders if the other is the Doctor.)

Alexios, Deimos of Kosmos

Trample
Alexios, Deimos of Kosmos attacks each combat if able, can't be sacrificed, and can't attack its owner.
At the beginning of each player's upkeep, that player gains control of Alexios, untaps it, and puts a +1/+1 counter on it. It gains haste until end of turn.

Bedevil

Destroy target artifact, creature, or planeswalker.

Mayhem Devil

Whenever a player sacrifices a permanent, Mayhem Devil deals 1 damage to any target.

Scytheclaw Raptor

Whenever a player casts a spell, if it's not their turn, Scytheclaw Raptor deals 4 damage to them.