Despise

Target opponent reveals their hand. You choose a creature or planeswalker card from it. That player discards that card.

Sign in Blood

Target player draws two cards and loses 2 life.

Liliana's Specter

Flying
When Liliana's Specter enters, each opponent discards a card.

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Court of Ambition

When Court of Ambition enters, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

Stabwhisker the Odious

At the beginning of each opponent's upkeep, that player loses 1 life for each card fewer than three in their hand.

Nezumi Shortfang

{1}{B}, {T}: Target opponent discards a card. Then if that player has no cards in hand, flip Nezumi Shortfang.

Nezumi Shortfang // Stabwhisker the Odious

Westgate Regent

Flying
Ward—Discard a card. (Whenever this creature becomes the target of a spell or ability an opponent controls, counter it unless that player discards a card.)
Whenever Westgate Regent deals combat damage to a player, put that many +1/+1 counters on it.

Elderfang Disciple

When Elderfang Disciple enters, each opponent discards a card.

Nezumi Informant

When Nezumi Informant enters, each opponent discards a card.

Bloodhusk Ritualist

Multikicker {B} (You may pay an additional {B} any number of times as you cast this spell.)
When Bloodhusk Ritualist enters, target opponent discards a card for each time it was kicked.

Black Cat

When Black Cat dies, target opponent discards a card at random.

Ayara, First of Locthwain

Whenever Ayara, First of Locthwain or another black creature you control enters, each opponent loses 1 life and you gain 1 life.
{T}, Sacrifice another black creature: Draw a card.

Tourach, Dread Cantor

Kicker {B}{B} (You may pay an additional {B}{B} as you cast this spell.)
Protection from white
Whenever an opponent discards a card, put a +1/+1 counter on Tourach, Dread Cantor.
When Tourach enters, if it was kicked, target opponent discards two cards at random.

Castle Locthwain

Castle Locthwain enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Ancient Craving

You draw three cards and you lose 3 life.

Deadbridge Shaman

When Deadbridge Shaman dies, target opponent discards a card.

Banshee of the Dread Choir

Myriad (Whenever this creature attacks, for each opponent other than defending player, you may create a token copy that's tapped and attacking that player or a planeswalker they control. Exile the tokens at end of combat.)
Whenever Banshee of the Dread Choir deals combat damage to a player, that player discards a card.

Ordeal of Erebos

Enchant creature
Whenever enchanted creature attacks, put a +1/+1 counter on it. Then if it has three or more +1/+1 counters on it, sacrifice Ordeal of Erebos.
When you sacrifice Ordeal of Erebos, target player discards two cards.

Hymn to Tourach

Target player discards two cards at random.

Burnished Hart

{3}, Sacrifice this creature: Search your library for up to two basic land cards, put them onto the battlefield tapped, then shuffle.

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Guul Draz Specter

Flying
Guul Draz Specter gets +3/+3 as long as an opponent has no cards in hand.
Whenever Guul Draz Specter deals combat damage to a player, that player discards a card.

Hopeless Nightmare

When Hopeless Nightmare enters, each opponent discards a card and loses 2 life.
When Hopeless Nightmare is put into a graveyard from the battlefield, scry 2.
{2}{B}: Sacrifice Hopeless Nightmare.

Ravenous Rats

When Ravenous Rats enters, target opponent discards a card.

Skullslither Worm

When Skullslither Worm enters, each opponent discards a card. For each opponent who can't, put two +1/+1 counters on Skullslither Worm.

Necrologia

Cast this spell only during your end step.
As an additional cost to cast this spell, pay X life.
Draw X cards.

Ghost-Lit Stalker

{4}{B}, {T}: Target player discards two cards. Activate only as a sorcery.
Channel — {5}{B}{B}, Discard Ghost-Lit Stalker: Target player discards four cards. Activate only as a sorcery.

Cackling Fiend

When Cackling Fiend enters, each opponent discards a card.

Mind Rot

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

The Raven Man

At the beginning of each end step, if a player discarded a card this turn, create a 1/1 black Bird creature token with flying and "This creature can't block."
{3}{B}, {T}: Each opponent discards a card. Activate only as a sorcery.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Fell Specter

Flying
When Fell Specter enters, target opponent discards a card.
Whenever an opponent discards a card, that player loses 2 life.

Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on Quest for the Nihil Stone.
At the beginning of each opponent's upkeep, if that player has no cards in hand and Quest for the Nihil Stone has two or more quest counters on it, you may have that player lose 5 life.

Abyssal Nocturnus

Whenever an opponent discards a card, Abyssal Nocturnus gets +2/+2 and gains fear until end of turn. (It can't be blocked except by artifact creatures and/or black creatures.)

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Tome of Legends

Tome of Legends enters with a page counter on it.
Whenever your commander enters or attacks, put a page counter on Tome of Legends.
{1}, {T}, Remove a page counter from Tome of Legends: Draw a card.

Charcoal Diamond

Charcoal Diamond enters tapped.
{T}: Add {B}.

Elvish Doomsayer

When Elvish Doomsayer dies, each opponent discards a card.

Gibbering Descent

At the beginning of each player's upkeep, that player loses 1 life and discards a card.
Hellbent — Skip your upkeep step if you have no cards in hand.
Madness {2}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Sol Ring

Harvest Fear

Target opponent discards two cards. (Then exile this card. You may cast the creature later from exile.)

Reaper of Night

Whenever Reaper of Night attacks, if defending player has two or fewer cards in hand, it gains flying until end of turn.

Reaper of Night // Harvest Fear

Burglar Rat

When this creature enters, each opponent discards a card.

Corrupt Court Official

When Corrupt Court Official enters, target opponent discards a card.

Davriel, Rogue Shadowmage

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, Davriel, Rogue Shadowmage deals 2 damage to them.
−1: Target player discards a card.

Raven's Crime

Target player discards a card.
Retrace (You may cast this card from your graveyard by discarding a land card in addition to paying its other costs.)

Hypnotic Specter

Flying
Whenever Hypnotic Specter deals damage to an opponent, that player discards a card at random.

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Village Rites

As an additional cost to cast this spell, sacrifice a creature.
Draw two cards.

Raiders' Wake

Whenever an opponent discards a card, that player loses 2 life.
Raid — At the beginning of your end step, if you attacked this turn, target opponent discards a card.

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Entropic Specter

Flying
As Entropic Specter enters, choose an opponent.
Entropic Specter's power and toughness are each equal to the number of cards in the chosen player's hand.
Whenever Entropic Specter deals damage to a player, that player discards a card.

Night's Whisper

Tinybones, Trinket Thief

At the beginning of each end step, if an opponent discarded a card this turn, you draw a card and you lose 1 life.
{4}{B}{B}: Each opponent with no cards in hand loses 10 life.

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Costly Plunder

As an additional cost to cast this spell, sacrifice an artifact or creature.
Draw two cards.

Braids's Frightful Return

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I — You may sacrifice a creature. If you do, each opponent discards a card.
II — Return target creature card from your graveyard to your hand.
III — Target opponent may sacrifice a nonland, nontoken permanent of their choice. If they don't, they lose 2 life and you draw a card.

Wrench Mind

Target player discards two cards unless they discard an artifact card.

Swamp

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Go Blank

Target player discards two cards. Then exile that player's graveyard.

Leshrac's Sigil

Whenever an opponent casts a green spell, you may pay {B}{B}. If you do, look at that player's hand and choose a card from it. The player discards that card.
{B}{B}: Return Leshrac's Sigil to its owner's hand.

Deadly Dispute

As an additional cost to cast this spell, sacrifice an artifact or creature.
Draw two cards and create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Unburden

Target player discards two cards.
Cycling {2} ({2}, Discard this card: Draw a card.)