Negate

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Queza, Augur of Agonies

Whenever you draw a card, target opponent loses 1 life and you gain 1 life.

Talisman of Progress

{T}: Add {C}.
{T}: Add {W} or {U}. Talisman of Progress deals 1 damage to you.

Inundated Archive

Inundated Archive enters tapped.
{T}: Add {U} or {B}.

Waterlogged Teachings

Search your library for an instant card or a card with flash, reveal it, put it into your hand, then shuffle.

Waterlogged Teachings // Inundated Archive

Teferi's Puzzle Box

At the beginning of each player's draw step, that player puts the cards in their hand on the bottom of their library in any order, then draws that many cards.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Terramorphic Expanse

{T}, Sacrifice Terramorphic Expanse: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Decanter of Endless Water

You have no maximum hand size.
{T}: Add one mana of any color.

Black Market Connections

At the beginning of your first main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It has every creature type.)

Ponder

Look at the top three cards of your library, then put them back in any order. You may shuffle.
Draw a card.

Teferi's Ageless Insight

If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Enduring Curiosity

Flash
Whenever a creature you control deals combat damage to a player, draw a card.
When Enduring Curiosity dies, if it was a creature, return it to the battlefield under its owner's control. It's an enchantment. (It's not a creature.)

Ghostly Prison

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Prairie Stream

({T}: Add {W} or {U}.)
Prairie Stream enters tapped unless you control two or more basic lands.

Orzhov Signet

Glacial Fortress

Glacial Fortress enters tapped unless you control a Plains or an Island.
{T}: Add {W} or {U}.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. Talisman of Dominance deals 1 damage to you.

Arcane Denial

Counter target spell. Its controller may draw up to two cards at the beginning of the next turn's upkeep.
You draw a card at the beginning of the next turn's upkeep.

Sol Ring

Approach of the Second Sun

If this spell was cast from your hand and you've cast another spell named Approach of the Second Sun this game, you win the game. Otherwise, put Approach of the Second Sun into its owner's library seventh from the top and you gain 7 life.

Mystic Sanctuary

({T}: Add {U}.)
Mystic Sanctuary enters tapped unless you control three or more other Islands.
When Mystic Sanctuary enters untapped, you may put target instant or sorcery card from your graveyard on top of your library.

An Offer You Can't Refuse

Counter target noncreature spell. Its controller creates two Treasure tokens. (They're artifacts with "{T}, Sacrifice this token: Add one mana of any color.")

Transcendence

You don't lose the game for having 0 or less life.
When you have 20 or more life, you lose the game.
Whenever you lose life, you gain 2 life for each 1 life you lost. (Damage dealt to you causes you to lose life.)

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Ominous Seas

Whenever you draw a card, put a foreshadow counter on Ominous Seas.
Remove eight foreshadow counters from Ominous Seas: Create an 8/8 blue Kraken creature token.
Cycling {2} ({2}, Discard this card: Draw a card.)

Don't Make a Sound

Counter target spell unless its controller pays {2}. If they do, surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Wizard Class

(Gain the next level as a sorcery to add its ability.)
You have no maximum hand size.
{2}{U}: Level 2
When this Class becomes level 2, draw two cards.
{4}{U}: Level 3
Whenever you draw a card, put a +1/+1 counter on target creature you control.

Azorius Chancery

Azorius Chancery enters tapped.
When Azorius Chancery enters, return a land you control to its owner's hand.
{T}: Add {W}{U}.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Get Out

Choose one —
• Counter target creature or enchantment spell.
• Return one or two target creatures and/or enchantments you own to your hand.

Soporific Springs

As Soporific Springs enters, you may pay 3 life. If you don't, it enters tapped.
{T}: Add {U}.

Sink into Stupor

Return target spell or nonland permanent an opponent controls to its owner's hand.

Sink into Stupor // Soporific Springs

Hall of Heliod's Generosity

{T}: Add {C}.
{1}{W}, {T}: Put target enchantment card from your graveyard on top of your library.

Evolving Wilds

{T}, Sacrifice this land: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Arcane Sanctum

Arcane Sanctum enters tapped.
{T}: Add {W}, {U}, or {B}.

Sign in Blood

Target player draws two cards and loses 2 life.

Path of Ancestry

Path of Ancestry enters tapped.
{T}: Add one mana of any color in your commander's color identity. When that mana is spent to cast a creature spell that shares a creature type with your commander, scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Propaganda

Windfall

Each player discards their hand, then draws cards equal to the greatest number of cards a player discarded this way.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Azorius Signet

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.

Command Tower

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Sunken Hollow

({T}: Add {U} or {B}.)
Sunken Hollow enters tapped unless you control two or more basic lands.

Howling Mine

At the beginning of each player's draw step, if Howling Mine is untapped, that player draws an additional card.

Triskaidekaphile

You have no maximum hand size.
At the beginning of your upkeep, if you have exactly thirteen cards in your hand, you win the game.
{3}{U}: Draw a card.

Rogue's Passage

{T}: Add {C}.
{4}, {T}: Target creature can't be blocked this turn.

Laboratory Maniac

If you would draw a card while your library has no cards in it, you win the game instead.

Generous Gift

Destroy target permanent. Its controller creates a 3/3 green Elephant creature token.

Pull from Tomorrow

Enduring Tenacity

Whenever you gain life, target opponent loses that much life.
When Enduring Tenacity dies, if it was a creature, return it to the battlefield under its owner's control. It's an enchantment. (It's not a creature.)

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Twist Reality

Choose one —
• Counter target spell.
• Manifest dread. (Look at the top two cards of your library. Put one onto the battlefield face down as a 2/2 creature and the other into your graveyard. Turn it face up any time for its mana cost if it's a creature card.)

Island

Swamp

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Elixir of Immortality

{2}, {T}: You gain 5 life. Shuffle Elixir of Immortality and your graveyard into their owner's library.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Counterspell

Hithlain Rope

Hithlain Rope can't be sacrificed.
{1}, {T}: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle. The player to your right gains control of Hithlain Rope.
{2}, {T}: Draw a card. The player to your right gains control of Hithlain Rope.

Plains

Dimir Signet

Murder

Exorcise

Exile target artifact, enchantment, or creature with power 4 or greater.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Fear of Sleep Paralysis

Flying
Eerie — Whenever Fear of Sleep Paralysis or another enchantment you control enters and whenever you fully unlock a Room, tap up to one target creature and put a stun counter on it.
Stun counters can't be removed from permanents your opponents control. (They won't untap if they have stun counters.)

Sphere of Safety

Creatures can't attack you or planeswalkers you control unless their controller pays {X} for each of those creatures, where X is the number of enchantments you control.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Pendant of Prosperity

Pendant of Prosperity enters under the control of an opponent of your choice.
{2}, {T}: Draw a card, then you may put a land card from your hand onto the battlefield. Pendant of Prosperity's owner draws a card, then that player may put a land card from their hand onto the battlefield.

Tolarian Winds

Discard all the cards in your hand, then draw that many cards.

Marina Vendrell's Grimoire

When Marina Vendrell's Grimoire enters, if you cast it, draw five cards.
You have no maximum hand size and don't lose the game for having 0 or less life.
Whenever you gain life, draw that many cards.
Whenever you lose life, discard that many cards. Then if you have no cards in hand, you lose the game.

Venser's Journal

You have no maximum hand size.
At the beginning of your upkeep, you gain 1 life for each card in your hand.

Folio of Fancies

Players have no maximum hand size.
{X}{X}, {T}: Each player draws X cards.
{2}{U}, {T}: Each opponent mills cards equal to the number of cards in their hand.