Niv-Mizzet, Guildpact

Flying, hexproof from multicolored
Whenever Niv-Mizzet, Guildpact deals combat damage to a player, it deals X damage to any target, target player draws X cards, and you gain X life, where X is the number of different color pairs among permanents you control that are exactly two colors.

Assassin's Trophy

Destroy target permanent an opponent controls. Its controller may search their library for a basic land card, put it onto the battlefield, then shuffle.

Cosmic Rebirth

Choose target permanent card in your graveyard. If it has mana value 3 or less, you may put it onto the battlefield. If you don't put it onto the battlefield, put it into your hand.
You gain 3 life.

Lonis, Cryptozoologist

Whenever another nontoken creature you control enters, investigate.
{T}, Sacrifice X Clues: Target opponent reveals the top X cards of their library. You may put a nonland permanent card with mana value X or less from among them onto the battlefield under your control. That player puts the rest on the bottom of their library in a random order.

Chromatic Lantern

Lands you control have "{T}: Add one mana of any color."
{T}: Add one mana of any color.

Ratadrabik of Urborg

Vigilance, ward {2}
Other Zombies you control have vigilance.
Whenever another legendary creature you control dies, create a token that's a copy of that creature, except it's not legendary and it's a 2/2 black Zombie in addition to its other colors and types.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Simic Charm

Choose one —
• Target creature gets +3/+3 until end of turn.
• Permanents you control gain hexproof until end of turn.
• Return target creature to its owner's hand.

Meren of Clan Nel Toth

Whenever another creature you control dies, you get an experience counter.
At the beginning of your end step, choose target creature card in your graveyard. If that card's mana value is less than or equal to the number of experience counters you have, return it to the battlefield. Otherwise, put it into your hand.

Basim Ibn Ishaq

Whenever you cast a historic spell, draw a card. Basim Ibn Ishaq can't be blocked this turn. This ability triggers only once each turn. (Artifacts, legendaries, and Sagas are historic.)
Whenever Basim Ibn Ishaq deals combat damage to a player, put a +1/+1 counter on it.

Knight of New Alara

Each other multicolored creature you control gets +1/+1 for each of its colors.

Rashmi, Eternities Crafter

Whenever you cast your first spell each turn, reveal the top card of your library. You may cast it without paying its mana cost if it's a spell with lesser mana value. If you don't cast it, put it into your hand.

Vraska Joins Up

When Vraska Joins Up enters, put a deathtouch counter on each creature you control.
Whenever a legendary creature you control deals combat damage to a player, draw a card.

Gold-Forged Thopteryx

Flying, lifelink
Each legendary permanent you control has ward {2}. (Whenever it becomes the target of a spell or ability an opponent controls, counter it unless that player pays {2}.)

Mortify

Dovin's Veto

This spell can't be countered.
Counter target noncreature spell.

Growth Spiral

Draw a card. You may put a land card from your hand onto the battlefield.

Aragorn, the Uniter

Whenever you cast a white spell, create a 1/1 white Human Soldier creature token.
Whenever you cast a blue spell, scry 2.
Whenever you cast a red spell, Aragorn, the Uniter deals 3 damage to target opponent.
Whenever you cast a green spell, target creature gets +4/+4 until end of turn.

Deflecting Palm

The next time a source of your choice would deal damage to you this turn, prevent that damage. If damage is prevented this way, Deflecting Palm deals that much damage to that source's controller.

Trostani, Three Whispers

{1}{G}: Target creature gains deathtouch until end of turn.
{G/W}: Target creature gains vigilance until end of turn.
{2}{W}: Target creature gains double strike until end of turn.

Tymna the Weaver

Lifelink
At the beginning of each of your postcombat main phases, you may pay X life, where X is the number of opponents that were dealt combat damage this turn. If you do, draw X cards.
Partner (You can have two commanders if both have partner.)

Leyline Prowler

Deathtouch, lifelink
{T}: Add one mana of any color.

Abstruse Appropriation

Devoid (This card has no color.)
Exile target nonland permanent. You may cast that card for as long as it remains exiled, and you may spend colorless mana as though it were mana of any color to cast that spell.

Warleader's Call

Creatures you control get +1/+1.
Whenever a creature you control enters, Warleader's Call deals 1 damage to each opponent.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Hajar, Loyal Bodyguard

Sacrifice Hajar, Loyal Bodyguard: Legendary creatures you control get +1/+0 and gain indestructible until end of turn.

Atzal, Cave of Eternity

(Transforms from Journey to Eternity.)
{T}: Add one mana of any color.
{3}{B}{G}, {T}: Return target creature card from your graveyard to the battlefield.

Journey to Eternity

Enchant creature you control
When enchanted creature dies, return it to the battlefield under your control, then return Journey to Eternity to the battlefield transformed under your control.

Journey to Eternity // Atzal, Cave of Eternity

Fists of the Demigod

Enchant creature
As long as enchanted creature is black, it gets +1/+1 and has wither. (It deals damage to creatures in the form of -1/-1 counters.)
As long as enchanted creature is red, it gets +1/+1 and has first strike.

Beledros Witherbloom

Flying
At the beginning of each upkeep, create a 1/1 black and green Pest creature token with "When this creature dies, you gain 1 life."
Pay 10 life: Untap all lands you control. Activate only once each turn.

Talion, the Kindly Lord

Flying
As Talion, the Kindly Lord enters, choose a number between 1 and 10.
Whenever an opponent casts a spell with mana value, power, or toughness equal to the chosen number, that player loses 2 life and you draw a card.

Scourge of the Nobilis

Enchant creature
As long as enchanted creature is red, it gets +1/+1 and has "{R/W}: This creature gets +1/+0 until end of turn."
As long as enchanted creature is white, it gets +1/+1 and has lifelink. (Damage dealt by the creature also causes its controller to gain that much life.)

General Ferrous Rokiric

Hexproof from monocolored
Whenever you cast a multicolored spell, create a 4/4 red and white Golem artifact creature token.

Glissa Sunslayer

First strike, deathtouch
Whenever Glissa Sunslayer deals combat damage to a player, choose one —
• You draw a card and you lose 1 life.
• Destroy target enchantment.
• Remove up to three counters from target permanent.

Rhythm of the Wild

Creature spells you control can't be countered.
Nontoken creatures you control have riot. (They enter with your choice of a +1/+1 counter or haste.)

Shaun, Father of Synths

Whenever you attack, you may create a tapped and attacking token that's a copy of target attacking legendary creature you control other than Shaun, except it's not legendary and it's a Synth artifact creature in addition to its other types.
When Shaun leaves the battlefield, exile all Synth tokens you control.

Steel of the Godhead

Enchant creature
As long as enchanted creature is white, it gets +1/+1 and has lifelink. (Damage dealt by the creature also causes its controller to gain that much life.)
As long as enchanted creature is blue, it gets +1/+1 and can't be blocked.

Clout of the Dominus

Enchant creature
As long as enchanted creature is blue, it gets +1/+1 and has shroud. (It can't be the target of spells or abilities.)
As long as enchanted creature is red, it gets +1/+1 and has haste.

Honest Rutstein

When Honest Rutstein enters, return target creature card from your graveyard to your hand.
Creature spells you cast cost {1} less to cast.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Pippin, Guard of the Citadel

Vigilance, ward {1}
{T}: Another target creature you control gains protection from the card type of your choice until end of turn. (It can't be blocked, targeted, dealt damage, enchanted, or equipped by anything of that type.)

Gift of the Deity

Enchant creature
As long as enchanted creature is black, it gets +1/+1 and has deathtouch. (Any amount of damage it deals to a creature is enough to destroy that creature.)
As long as enchanted creature is green, it gets +1/+1 and all creatures able to block it do so.

Tome of the Guildpact

Whenever you cast a multicolored spell, draw a card.
{T}: Add one mana of any color.

Arbaaz Mir

Whenever Arbaaz Mir or another nontoken historic permanent you control enters, Arbaaz Mir deals 1 damage to each opponent and you gain 1 life. (Artifacts, legendaries, and Sagas are historic.)

Faeburrow Elder

Vigilance
Faeburrow Elder gets +1/+1 for each color among permanents you control.
{T}: For each color among permanents you control, add one mana of that color.

Sol Ring

Favor of the Overbeing

Enchant creature
As long as enchanted creature is green, it gets +1/+1 and has vigilance.
As long as enchanted creature is blue, it gets +1/+1 and has flying.

Reborn Hope

Return target multicolored card from your graveyard to your hand.

Inkshield

Prevent all combat damage that would be dealt to you this turn. For each 1 damage prevented this way, create a 2/1 white and black Inkling creature token with flying.

Edge of the Divinity

Enchant creature
As long as enchanted creature is white, it gets +1/+2.
As long as enchanted creature is black, it gets +2/+1.

Helm of the Ghastlord

Enchant creature
As long as enchanted creature is blue, it gets +1/+1 and has "Whenever this creature deals damage to an opponent, draw a card."
As long as enchanted creature is black, it gets +1/+1 and has "Whenever this creature deals damage to an opponent, that player discards a card."

Rakdos Charm

Choose one —
• Exile target player's graveyard.
• Destroy target artifact.
• Each creature deals 1 damage to its controller.

Kutzil, Malamet Exemplar

Your opponents can't cast spells during your turn.
Whenever one or more creatures you control each with power greater than its base power deals combat damage to a player, draw a card.

Urza's Filter

Multicolored spells cost {2} less to cast.

Azorius Charm

Choose one —
• Creatures you control gain lifelink until end of turn.
• Draw a card.
• Put target attacking or blocking creature on top of its owner's library.

Iroas, God of Victory

Indestructible
As long as your devotion to red and white is less than seven, Iroas isn't a creature.
Creatures you control have menace.
Prevent all damage that would be dealt to attacking creatures you control.

Prosperous Partnership

When Prosperous Partnership enters, create two 1/1 green and white Citizen creature tokens.
Tap three untapped creatures you control: Create a Treasure token.

Boros Charm

Choose one —
• Boros Charm deals 4 damage to target player or planeswalker.
• Permanents you control gain indestructible until end of turn.
• Target creature gains double strike until end of turn.

Jhoira, Weatherlight Captain

Whenever you cast a historic spell, draw a card. (Artifacts, legendaries, and Sagas are historic.)

Bigger on the Inside

Enchant artifact or land
Enchanted permanent has "{T}: Target player adds two mana of any one color. The next spell they cast this turn has cascade." (When they cast their next spell, they exile cards from the top of their library until they exile a nonland card that costs less. They may cast it without paying its mana cost. They put the exiled cards on the bottom in a random order.)

Aurelia, the Law Above

Flying, vigilance, haste
Whenever a player attacks with three or more creatures, you draw a card.
Whenever a player attacks with five or more creatures, Aurelia, the Law Above deals 3 damage to each of your opponents and you gain 3 life.

Shielding Plax

({G/U} can be paid with either {G} or {U}.)
Enchant creature
When Shielding Plax enters, draw a card.
Enchanted creature can't be the target of spells or abilities your opponents control.

Lotho, Corrupt Shirriff

Whenever a player casts their second spell each turn, you lose 1 life and create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Shield of the Oversoul

Enchant creature
As long as enchanted creature is green, it gets +1/+1 and has indestructible. (Damage and effects that say "destroy" don't destroy it. If its toughness is 0 or less, it's still put into its owner's graveyard.)
As long as enchanted creature is white, it gets +1/+1 and has flying.

Jegantha, the Wellspring

Companion — No card in your starting deck has more than one of the same mana symbol in its mana cost. (If this card is your chosen companion, you may put it into your hand from outside the game for {3} as a sorcery.)
{T}: Add {W}{U}{B}{R}{G}. This mana can't be spent to pay generic mana costs.

Niv-Mizzet, Supreme

Flying, hexproof from monocolored
Each instant and sorcery card in your graveyard that's exactly two colors has jump-start. (You may cast that card from your graveyard by discarding a card in addition to paying its other costs. Then exile it.)

Bruse Tarl, Boorish Herder

Whenever Bruse Tarl, Boorish Herder enters or attacks, target creature you control gains double strike and lifelink until end of turn.
Partner (You can have two commanders if both have partner.)

Mirari's Wake

Creatures you control get +1/+1.
Whenever you tap a land for mana, add one mana of any type that land produced.

Rakdos, Patron of Chaos

Flying, trample
At the beginning of your end step, target opponent may sacrifice two nonland, nontoken permanents. If they don't, you draw two cards.

Inga and Esika

Creatures you control have vigilance and "{T}: Add one mana of any color. Spend this mana only to cast a creature spell."
Whenever you cast a creature spell, if three or more mana from creatures was spent to cast it, draw a card.

Countersquall

Counter target noncreature spell. Its controller loses 2 life.

Runes of the Deus

Enchant creature
As long as enchanted creature is red, it gets +1/+1 and has double strike. (It deals both first-strike and regular combat damage.)
As long as enchanted creature is green, it gets +1/+1 and has trample.