Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Day of Judgment

Sol Ring

Loran's Escape

Target artifact or creature gains hexproof and indestructible until end of turn. Scry 1.

Darksteel Citadel

Depopulate

Each player who controls a multicolored creature draws a card. Then destroy all creatures.

End Hostilities

Destroy all creatures and all permanents attached to creatures.

Deadly Cover-Up

As an additional cost to cast this spell, you may collect evidence 6.
Destroy all creatures. If evidence was collected, exile a card from an opponent's graveyard. Then search its owner's graveyard, hand, and library for any number of cards with that name and exile them. That player shuffles, then draws a card for each card exiled from their hand this way.

Mandate of Abaddon

Choose target creature you control. Destroy all creatures with power less than that creature's power.

Winds of Rath

Destroy all creatures that aren't enchanted. They can't be regenerated.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Surge of Salvation

You and permanents you control gain hexproof until end of turn. Prevent all damage that black and/or red sources would deal to creatures you control this turn.

Blood Money

Destroy all creatures. For each nontoken creature destroyed this way, you create a tapped Treasure token.

The Nipton Lottery

Choose a creature at random. You gain control of that creature until end of turn. Untap it. It gains haste until end of turn. Then destroy all other creatures.

Winds of Abandon

Exile target creature you don't control. For each creature exiled this way, its controller searches their library for a basic land card. Those players put those cards onto the battlefield tapped, then shuffle.
Overload {4}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Zurgo Helmsmasher

Haste
Zurgo Helmsmasher attacks each combat if able.
During your turn, Zurgo Helmsmasher has indestructible.
Whenever a creature dealt damage by Zurgo Helmsmasher this turn dies, put a +1/+1 counter on Zurgo Helmsmasher.

Sublime Exhalation

Undaunted (This spell costs {1} less to cast for each opponent.)
Destroy all creatures.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Shardmage's Rescue

Flash
Enchant creature you control
As long as Shardmage's Rescue entered this turn, enchanted creature has hexproof.
Enchanted creature gets +1/+1.

Rout

You may cast Rout as though it had flash if you pay {2} more to cast it. (You may cast it any time you could cast an instant.)
Destroy all creatures. They can't be regenerated.

Nevinyrral's Disk

Nevinyrral's Disk enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Krenko's Buzzcrusher

Flying, trample
When Krenko's Buzzcrusher enters, for each player, destroy up to one nonbasic land that player controls. For each land destroyed this way, its controller may search their library for a basic land card, put it onto the battlefield tapped, then shuffle.

Call of the Ring

At the beginning of your upkeep, the Ring tempts you.
Whenever you choose a creature as your Ring-bearer, you may pay 2 life. If you do, draw a card.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Damnation

Destroy all creatures. They can't be regenerated.

Cascading Cataracts

Indestructible
{T}: Add {C}.
{5}, {T}: Add five mana in any combination of colors.

Cleansing Wildfire

Destroy target land. Its controller may search their library for a basic land card, put it onto the battlefield tapped, then shuffle.
Draw a card.

Deep Gnome Terramancer

Flash
Mold Earth — Whenever one or more lands enter under an opponent's control without being played, you may search your library for a Plains card, put it onto the battlefield tapped, then shuffle. Do this only once each turn.

Shadowspear

Equipped creature gets +1/+1 and has trample and lifelink.
{1}: Permanents your opponents control lose hexproof and indestructible until end of turn.
Equip {2}

Coveted Jewel

When Coveted Jewel enters, draw three cards.
{T}: Add three mana of any one color.
Whenever one or more creatures an opponent controls attack you and aren't blocked, that player draws three cards and gains control of Coveted Jewel. Untap it.

Beaming Defiance

Target creature you control gets +2/+2 and gains hexproof until end of turn. (It can't be the target of spells or abilities your opponents control.)

Planar Collapse

At the beginning of your upkeep, if there are four or more creatures on the battlefield, sacrifice Planar Collapse and destroy all creatures. They can't be regenerated.

Eye of Vecna

When Eye of Vecna enters, you draw a card and you lose 2 life.
At the beginning of your upkeep, you may pay {2}. If you do, you draw a card and you lose 2 life.

Shatter the Sky

Each player who controls a creature with power 4 or greater draws a card. Then destroy all creatures.

Rustvale Bridge

Rustvale Bridge enters tapped.
Indestructible
{T}: Add {R} or {W}.

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Catastrophe

Destroy all lands or all creatures. Creatures destroyed this way can't be regenerated.

Thraben Inspector

When Thraben Inspector enters, investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")

No Witnesses

Each player who controls the most creatures investigates. Then destroy all creatures. (To investigate, create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")

From the Ashes

Destroy all nonbasic lands. For each land destroyed this way, its controller may search their library for a basic land card and put it onto the battlefield. Then each player who searched their library this way shuffles.

Drossforge Bridge

Drossforge Bridge enters tapped.
Indestructible
{T}: Add {B} or {R}.

Cleansing Nova

Choose one —
• Destroy all creatures.
• Destroy all artifacts and enchantments.

Vanquish the Horde

This spell costs {1} less to cast for each creature on the battlefield.
Destroy all creatures.

Wrath of God

Doomskar

Destroy all creatures.
Foretell {1}{W}{W} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Akroma's Vengeance

Destroy all artifacts, creatures, and enchantments.
Cycling {3} ({3}, Discard this card: Draw a card.)

Champion's Helm

Equipped creature gets +2/+2.
As long as equipped creature is legendary, it has hexproof. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Final Act

Choose one or more —
• Destroy all creatures.
• Destroy all planeswalkers.
• Destroy all battles.
• Exile all graveyards.
• Each opponent loses all counters.

Blacksmith's Skill

Target permanent gains hexproof and indestructible until end of turn. If it's an artifact creature, it gets +2/+2 until end of turn.

Goldmire Bridge

Goldmire Bridge enters tapped.
Indestructible
{T}: Add {W} or {B}.

Novice Inspector

When Novice Inspector enters, investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")

What Must Be Done

Choose one —
• Let the World Burn — Destroy all artifacts and creatures.
• Release Juno — Return target historic permanent card from your graveyard to the battlefield. It enters with two additional +1/+1 counters on it if it's a creature. (Artifacts, legendaries, and Sagas are historic.)