Grievous Wound

Enchant player
Enchanted player can't gain life.
Whenever enchanted player is dealt damage, they lose half their life, rounded up.

Ob Nixilis, Captive Kingpin

Flying, trample
Whenever one or more opponents each lose exactly 1 life, put a +1/+1 counter on Ob Nixilis, Captive Kingpin. Exile the top card of your library. Until your next end step, you may play that card.

Nightshade Harvester

Whenever a land an opponent controls enters, that player loses 1 life. Put a +1/+1 counter on Nightshade Harvester.

Kederekt Parasite

Whenever an opponent draws a card, if you control a red permanent, you may have Kederekt Parasite deal 1 damage to that player.

Revenge of Ravens

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life and you gain 1 life.

Swamp

Polluted Bonds

Whenever a land an opponent controls enters, that player loses 2 life and you gain 2 life.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Barbed Wire

At the beginning of each player's upkeep, Barbed Wire deals 1 damage to that player.
{2}: Prevent the next 1 damage that would be dealt by Barbed Wire this turn.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Decree of Pain

Destroy all creatures. They can't be regenerated. Draw a card for each creature destroyed this way.
Cycling {3}{B}{B} ({3}{B}{B}, Discard this card: Draw a card.)
When you cycle Decree of Pain, all creatures get -2/-2 until end of turn.

Kardur, Doomscourge

When Kardur, Doomscourge enters, until your next turn, creatures your opponents control attack each combat if able and attack a player other than you if able.
Whenever an attacking creature dies, each opponent loses 1 life and you gain 1 life.

Faithless Looting

Draw two cards, then discard two cards.
Flashback {2}{R} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Witch's Clinic

{T}: Add {C}.
{2}, {T}: Target commander gains lifelink until end of turn.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Solemn Simulacrum

When Solemn Simulacrum enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When Solemn Simulacrum dies, you may draw a card.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Pyrohemia

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pyrohemia.
{R}: Pyrohemia deals 1 damage to each creature and each player.

The Rollercrusher Ride

Delirium — If a source you control would deal noncombat damage to a permanent or player while there are four or more card types among cards in your graveyard, it deals double that damage instead.
When The Rollercrusher Ride enters, it deals X damage to each of up to X target creatures.

Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Grab the Prize

As an additional cost to cast this spell, discard a card.
Draw two cards. If the discarded card wasn't a land card, Grab the Prize deals 2 damage to each opponent.

Blood Seeker

Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Razorkin Needlehead

Razorkin Needlehead has first strike during your turn.
Whenever an opponent draws a card, Razorkin Needlehead deals 1 damage to them.

Brash Taunter

Indestructible
Whenever Brash Taunter is dealt damage, it deals that much damage to target opponent.
{2}{R}, {T}: Brash Taunter fights another target creature.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Abrade

Choose one —
• Abrade deals 3 damage to target creature.
• Destroy target artifact.

Theater of Horrors

At the beginning of your upkeep, exile the top card of your library.
During your turn, if an opponent lost life this turn, you may play lands and cast spells from among cards exiled with Theater of Horrors.
{3}{R}: Theater of Horrors deals 1 damage to target opponent or planeswalker.

Screaming Nemesis

Haste
Whenever Screaming Nemesis is dealt damage, it deals that much damage to any other target. If a player is dealt damage this way, they can't gain life for the rest of the game.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Roiling Vortex

At the beginning of each player's upkeep, Roiling Vortex deals 1 damage to them.
Whenever a player casts a spell, if no mana was spent to cast that spell, Roiling Vortex deals 5 damage to that player.
{R}: Your opponents can't gain life this turn.

Rug of Smothering

Flying
Whenever a player casts a spell, they lose 1 life for each spell they've cast this turn.

Mountain

Suspended Sentence

Destroy target creature an opponent controls. That player loses 3 life. Exile Suspended Sentence with three time counters on it.
Suspend 3—{1}{B} (Rather than cast this card from your hand, you may pay {1}{B} and exile it with three time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)

Spiteful Visions

At the beginning of each player's draw step, that player draws an additional card.
Whenever a player draws a card, Spiteful Visions deals 1 damage to that player.

Evolving Wilds

{T}, Sacrifice Evolving Wilds: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Valgavoth, Harrower of Souls

Flying
Ward—Pay 2 life.
Whenever an opponent loses life for the first time during each of their turns, put a +1/+1 counter on Valgavoth, Harrower of Souls and draw a card.

Pestilence

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pestilence.
{B}: Pestilence deals 1 damage to each creature and each player.

Persistent Constrictor

At the beginning of each opponent's upkeep, they lose 1 life and you put a -1/-1 counter on up to one target creature they control.
Persist (When this creature dies, if it had no -1/-1 counters on it, return it to the battlefield under its owner's control with a -1/-1 counter on it.)

Orcish Bowmasters

Flash
When Orcish Bowmasters enters and whenever an opponent draws a card except the first one they draw in each of their draw steps, Orcish Bowmasters deals 1 damage to any target. Then amass Orcs 1.

Smoldering Marsh

({T}: Add {B} or {R}.)
Smoldering Marsh enters tapped unless you control two or more basic lands.

Star Athlete

Menace
Whenever Star Athlete attacks, choose up to one target nonland permanent. Its controller may sacrifice it. If they don't, Star Athlete deals 5 damage to that player.
Blitz {3}{R} (If you cast this spell for its blitz cost, it gains haste and "When this creature dies, draw a card." Sacrifice it at the beginning of the next end step.)

Blazemire Verge

{T}: Add {B}.
{T}: Add {R}. Activate only if you control a Swamp or a Mountain.

Raucous Theater

({T}: Add {B} or {R}.)
Raucous Theater enters tapped.
When Raucous Theater enters, surveil 1. (Look at the top card of your library. You may put it into your graveyard.)

Kaervek the Merciless

Whenever an opponent casts a spell, Kaervek the Merciless deals damage equal to that spell's mana value to any target.

Rakdos, Lord of Riots

You can't cast this spell unless an opponent lost life this turn.
Flying, trample
Creature spells you cast cost {1} less to cast for each 1 life your opponents have lost this turn.

Reliquary Tower

Mayhem Devil

Whenever a player sacrifices a permanent, Mayhem Devil deals 1 damage to any target.

Temple of Malice

Temple of Malice enters tapped.
When Temple of Malice enters, scry 1.
{T}: Add {B} or {R}.

Terminate

Destroy target creature. It can't be regenerated.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Untimely Malfunction

Choose one —
• Destroy target artifact.
• Change the target of target spell or ability with a single target.
• One or two target creatures can't block this turn.

The Lord of Pain

Menace
Your opponents can't gain life.
Whenever a player casts their first spell each turn, choose another target player. The Lord of Pain deals damage equal to that spell's mana value to the chosen player.

Rampaging Ferocidon

Menace
Players can't gain life.
Whenever another creature enters, Rampaging Ferocidon deals 1 damage to that creature's controller.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Luxury Suite

Luxury Suite enters tapped unless you have two or more opponents.
{T}: Add {B} or {R}.

Sulfurous Springs

{T}: Add {C}.
{T}: Add {B} or {R}. Sulfurous Springs deals 1 damage to you.

Shivan Gorge

{T}: Add {C}.
{2}{R}, {T}: Shivan Gorge deals 1 damage to each opponent.

Torture Pit

If a source you control would deal noncombat damage to an opponent, it deals that much damage plus 2 instead.
(You may cast either half. That door unlocks on the battlefield. As a sorcery, you may pay the mana cost of a locked door to unlock it.)

Spiked Corridor

When you unlock this door, create three 1/1 red Devil creature tokens with "When this creature dies, it deals 1 damage to any target."
(You may cast either half. That door unlocks on the battlefield. As a sorcery, you may pay the mana cost of a locked door to unlock it.)

Spiked Corridor // Torture Pit

Fear of Burning Alive

When Fear of Burning Alive enters, it deals 4 damage to each opponent.
Delirium — Whenever a source you control deals noncombat damage to an opponent, if there are four or more card types among cards in your graveyard, Fear of Burning Alive deals that amount of damage to target creature that player controls.

Mogis, God of Slaughter

Indestructible
As long as your devotion to black and red is less than seven, Mogis isn't a creature.
At the beginning of each opponent's upkeep, Mogis deals 2 damage to that player unless they sacrifice a creature.

Spellshock

Whenever a player casts a spell, Spellshock deals 2 damage to that player.

Mithril Coat

Flash
Indestructible
When Mithril Coat enters, attach it to target legendary creature you control.
Equipped creature has indestructible.
Equip {3}

Dragonskull Summit

Dragonskull Summit enters tapped unless you control a Swamp or a Mountain.
{T}: Add {B} or {R}.

Copper Tablet

At the beginning of each player's upkeep, Copper Tablet deals 1 damage to that player.

Talisman of Indulgence

{T}: Add {C}.
{T}: Add {B} or {R}. Talisman of Indulgence deals 1 damage to you.

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Citadel of Pain

At the beginning of each player's end step, Citadel of Pain deals X damage to that player, where X is the number of untapped lands they control.

Sadistic Shell Game

Starting with the next opponent in turn order, each player chooses a creature you don't control. Destroy the chosen creatures.

Sinister Monolith

At the beginning of combat on your turn, each opponent loses 1 life and you gain 1 life.
{T}, Pay 2 life, Sacrifice Sinister Monolith: Draw two cards. Activate only as a sorcery.

Command Tower

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Massacre Wurm

When Massacre Wurm enters, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Basilisk Collar

Equipped creature has deathtouch and lifelink.
Equip {2}

Sulfuric Vortex

At the beginning of each player's upkeep, Sulfuric Vortex deals 2 damage to that player.
If a player would gain life, that player gains no life instead.

Enchanter's Bane

At the beginning of your end step, target enchantment deals damage equal to its mana value to its controller unless that player sacrifices it.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Manabarbs

Whenever a player taps a land for mana, Manabarbs deals 1 damage to that player.

Forsaken Wastes

Players can't gain life.
At the beginning of each player's upkeep, that player loses 1 life.
Whenever Forsaken Wastes becomes the target of a spell, that spell's controller loses 5 life.

Chandra, Awakened Inferno

This spell can't be countered.
+2: Each opponent gets an emblem with "At the beginning of your upkeep, this emblem deals 1 damage to you."
−3: Chandra, Awakened Inferno deals 3 damage to each non-Elemental creature.
−X: Chandra, Awakened Inferno deals X damage to target creature or planeswalker. If a permanent dealt damage this way would die this turn, exile it instead.

Foreboding Ruins

As Foreboding Ruins enters, you may reveal a Swamp or Mountain card from your hand. If you don't, Foreboding Ruins enters tapped.
{T}: Add {B} or {R}.

Solphim, Mayhem Dominus

If a source you control would deal noncombat damage to an opponent or a permanent an opponent controls, it deals double that damage to that player or permanent instead.
{1}{R/P}{R/P}, Discard two cards: Put an indestructible counter on Solphim, Mayhem Dominus. ({R/P} can be paid with either {R} or 2 life.)

Tainted Peak

{T}: Add {C}.
{T}: Add {B} or {R}. Activate only if you control a Swamp.

Graven Cairns

{T}: Add {C}.
{B/R}, {T}: Add {B}{B}, {B}{R}, or {R}{R}.

Leechridden Swamp

({T}: Add {B}.)
Leechridden Swamp enters tapped.
{B}, {T}: Each opponent loses 1 life. Activate only if you control two or more black permanents.

Platinum Emperion

Your life total can't change. (You can't gain or lose life. You can't pay any amount of life except 0.)