Sign in Blood

Target player draws two cards and loses 2 life.

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Vampire Nighthawk

Flying
Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Spectator Seating

Spectator Seating enters tapped unless you have two or more opponents.
{T}: Add {R} or {W}.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Soul's Attendant

Whenever another creature enters, you may gain 1 life.

Fall of Cair Andros

Whenever a creature an opponent controls is dealt excess noncombat damage, amass Orcs X, where X is that excess damage. (Put X +1/+1 counters on an Army you control. It's also an Orc. If you don't control an Army, create a 0/0 black Orc Army creature token first.)
{7}{R}: Fall of Cair Andros deals 7 damage to target creature.

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Ruinous Ultimatum

Destroy all nonland permanents your opponents control.

Plains

Nomad Outpost

Nomad Outpost enters tapped.
{T}: Add {R}, {W}, or {B}.

Font of Agonies

Whenever you pay life, put that many blood counters on Font of Agonies.
{1}{B}, Remove four blood counters from Font of Agonies: Destroy target creature.

Exotic Orchard

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters, you may pay 2 life. If you don't, it enters tapped.

Swamp

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter tapped.

Elenda, the Dusk Rose

Lifelink
Whenever another creature dies, put a +1/+1 counter on Elenda, the Dusk Rose.
When Elenda dies, create X 1/1 white Vampire creature tokens with lifelink, where X is Elenda's power.

Children of Korlis

Sacrifice Children of Korlis: You gain life equal to the life you've lost this turn. (Damage causes loss of life.)

Celestine, the Living Saint

Flying, lifelink
Healing Tears — At the beginning of your end step, return target creature card with mana value X or less from your graveyard to the battlefield, where X is the amount of life you gained this turn.

Night's Whisper

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Verrak, Warped Sengir

Flying, deathtouch, lifelink
Whenever you activate an ability that isn't a mana ability, if life was paid to activate it, you may pay that much life again. If you do, copy that ability. You may choose new targets for the copy.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Rodolf Duskbringer

Flying, deathtouch, lifelink
Whenever you gain life, Rodolf Duskbringer gains indestructible until end of turn.
At the beginning of your end step, you may pay {1}{W/B}. When you do, return target creature card with mana value X or less from your graveyard to the battlefield, where X is the amount of life you gained this turn.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Luxury Suite

Luxury Suite enters tapped unless you have two or more opponents.
{T}: Add {B} or {R}.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Sword of the Animist

Equipped creature gets +1/+1.
Whenever equipped creature attacks, you may search your library for a basic land card, put it onto the battlefield tapped, then shuffle.
Equip {2}

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Sacred Foundry

({T}: Add {R} or {W}.)
As Sacred Foundry enters, you may pay 2 life. If you don't, it enters tapped.

Savai Triome

({T}: Add {R}, {W}, or {B}.)
Savai Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Cleric Class

(Gain the next level as a sorcery to add its ability.)
If you would gain life, you gain that much life plus 1 instead.
{3}{W}: Level 2
Whenever you gain life, put a +1/+1 counter on target creature you control.
{4}{W}: Level 3
When this Class becomes level 3, return target creature card from your graveyard to the battlefield. You gain life equal to that creature's toughness.

Isolated Chapel

Isolated Chapel enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Crackling Doom

Crackling Doom deals 2 damage to each opponent. Each opponent sacrifices a creature with the greatest power among creatures that player controls.

Generous Gift

Destroy target permanent. Its controller creates a 3/3 green Elephant creature token.

Rakdos Signet

Soul Warden

Whenever another creature enters, you gain 1 life.

Rogue's Passage

{T}: Add {C}.
{4}, {T}: Target creature can't be blocked this turn.

Terminate

Destroy target creature. It can't be regenerated.

Venser's Journal

You have no maximum hand size.
At the beginning of your upkeep, you gain 1 life for each card in your hand.

Force of Despair

If it's not your turn, you may exile a black card from your hand rather than pay this spell's mana cost.
Destroy all creatures that entered this turn.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Boros Charm

Choose one —
• Boros Charm deals 4 damage to target player or planeswalker.
• Permanents you control gain indestructible until end of turn.
• Target creature gains double strike until end of turn.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Shattered Sanctum

Shattered Sanctum enters tapped unless you control two or more other lands.
{T}: Add {W} or {B}.

Nykthos Paragon

Whenever you gain life, you may put that many +1/+1 counters on each creature you control. Do this only once each turn.

Nighthawk Scavenger

Flying, deathtouch, lifelink
Nighthawk Scavenger's power is equal to 1 plus the number of card types among cards in your opponents' graveyards.

Mountain

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Orzhov Signet

Terramorphic Expanse

{T}, Sacrifice Terramorphic Expanse: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Twilight Prophet

Flying
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your upkeep, if you have the city's blessing, reveal the top card of your library and put it into your hand. Each opponent loses X life and you gain X life, where X is that card's mana value.

Chandra's Ignition

Target creature you control deals damage equal to its power to each other creature and each opponent.

Kabira Crossroads

Kabira Crossroads enters tapped.
When Kabira Crossroads enters, you gain 2 life.
{T}: Add {W}.

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Thought Vessel

Land Tax

At the beginning of your upkeep, if an opponent controls more lands than you, you may search your library for up to three basic land cards, reveal them, put them into your hand, then shuffle.

Licia, Sanguine Tribune

This spell costs {1} less to cast for each 1 life you gained this turn.
First strike, lifelink
Pay 5 life: Put three +1/+1 counters on Licia, Sanguine Tribune. Activate only during your turn and only once each turn.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Mortify

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, Serra Ascendant gets +5/+5 and has flying.

Whispersilk Cloak

Equipped creature can't be blocked and has shroud. (It can't be the target of spells or abilities.)
Equip {2}

Blood Crypt

({T}: Add {B} or {R}.)
As Blood Crypt enters, you may pay 2 life. If you don't, it enters tapped.

Excalibur, Sword of Eden

This spell costs {X} less to cast, where X is the total mana value of historic permanents you control. (Artifacts, legendaries, and Sagas are historic.)
Equipped creature gets +10/+0 and has vigilance.
Equip legendary creature {2}

Vona, Butcher of Magan

Vigilance, lifelink
{T}, Pay 7 life: Destroy target nonland permanent. Activate only during your turn.

Caduceus, Staff of Hermes

Equipped creature has lifelink.
As long as you have 30 or more life, equipped creature gets +5/+5 and has indestructible and "Prevent all damage that would be dealt to this creature."
Equip {W}{W}

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Divinity of Pride

Flying, lifelink
Divinity of Pride gets +4/+4 as long as you have 25 or more life.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Conqueror's Flail

Equipped creature gets +1/+1 for each color among permanents you control.
As long as Conqueror's Flail is attached to a creature, your opponents can't cast spells during your turn.
Equip {2}

Akroma's Will

Choose one. If you control a commander as you cast this spell, you may choose both instead.
• Creatures you control gain flying, vigilance, and double strike until end of turn.
• Creatures you control gain lifelink, indestructible, and protection from each color until end of turn.

Sol Ring

Mythos of Snapdax

Each player chooses an artifact, a creature, an enchantment, and a planeswalker from among the nonland permanents they control, then sacrifices the rest. If {B}{R} was spent to cast this spell, you choose the permanents for each player instead.

Command Tower

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Dragonskull Summit

Dragonskull Summit enters tapped unless you control a Swamp or a Mountain.
{T}: Add {B} or {R}.

Stinging Study

You draw X cards and you lose X life, where X is the mana value of a commander you own on the battlefield or in the command zone.

Vault of Champions

Vault of Champions enters tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Charismatic Conqueror

Vigilance
Whenever an artifact or creature an opponent controls enters untapped, they may tap that permanent. If they don't, you create a 1/1 white Vampire creature token with lifelink.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Evolving Wilds

{T}, Sacrifice this land: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Black Market

Whenever a creature dies, put a charge counter on Black Market.
At the beginning of your first main phase, add {B} for each charge counter on Black Market.

Boon Reflection

If you would gain life, you gain twice that much life instead.

Markov Purifier

Lifelink
At the beginning of your end step, if you gained life this turn, you may pay {2}. If you do, draw a card.