Go for the Throat

Rush of Dread

Spree (Choose one or more additional costs.)
+ {1} — Target opponent sacrifices half the creatures they control of their choice, rounded up.
+ {2} — Target opponent discards half the cards in their hand, rounded up.
+ {2} — Target opponent loses half their life, rounded up.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Dead Weight

Enchant creature
Enchanted creature gets -2/-2.

Swamp

Moonstone Harbinger

Flying, deathtouch
Whenever you gain or lose life during your turn, Bats you control get +1/+0 and gain deathtouch until end of turn. This ability triggers only once each turn.

Sheoldred's Edict

Choose one —
• Each opponent sacrifices a nontoken creature of their choice.
• Each opponent sacrifices a creature token of their choice.
• Each opponent sacrifices a planeswalker of their choice.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Bandit's Talent

(Gain the next level as a sorcery to add its ability.)
When Bandit's Talent enters, each opponent discards two cards unless they discard a nonland card.
{B}: Level 2
At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 2 life.
{3}{B}: Level 3
At the beginning of your draw step, draw an additional card for each opponent who has one or fewer cards in hand.

Deep-Cavern Bat

Flying, lifelink
When Deep-Cavern Bat enters, look at target opponent's hand. You may exile a nonland card from it until Deep-Cavern Bat leaves the battlefield.

Nezumi Informant

When Nezumi Informant enters, each opponent discards a card.

Ruthless Negotiation

Target opponent exiles a card from their hand. If this spell was cast from a graveyard, draw a card.
Flashback {4}{B} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Pile On

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Destroy target creature or planeswalker. Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Gnawing Vermin

When Gnawing Vermin enters, target player mills two cards.
When Gnawing Vermin dies, target creature you don't control gets -1/-1 until end of turn.

Polygraph Orb

When Polygraph Orb enters, look at the top four cards of your library. Put two of them into your hand and the rest into your graveyard. You lose 2 life.
{2}, {T}, Collect evidence 3: Each opponent loses 3 life unless they discard a card or sacrifice a creature. (To collect evidence 3, exile cards with total mana value 3 or greater from your graveyard.)

Dread Osseosaur

Menace
Whenever Dread Osseosaur enters or attacks, you may mill two cards. (You may put the top two cards of your library into your graveyard.)

Visage of Dread

When Visage of Dread enters, target opponent reveals their hand. You choose an artifact or creature card from it. That player discards that card.
Craft with two creatures {5}{B} ({5}{B}, Exile this artifact, Exile the two from among creatures you control and/or creature cards in your graveyard: Return this card transformed under its owner's control. Craft only as a sorcery.)

Visage of Dread // Dread Osseosaur

Hopeless Nightmare

When Hopeless Nightmare enters, each opponent discards a card and loses 2 life.
When Hopeless Nightmare is put into a graveyard from the battlefield, scry 2.
{2}{B}: Sacrifice Hopeless Nightmare.

The End

This spell costs {2} less to cast if your life total is 5 or less.
Exile target creature or planeswalker. Search its controller's graveyard, hand, and library for any number of cards with the same name as that permanent and exile them. That player shuffles, then draws a card for each card exiled from their hand this way.

Slice from the Shadows

This spell can't be countered. (This includes by the ward ability.)
Target creature gets -X/-X until end of turn.

Cut Down

Destroy target creature with total power and toughness 5 or less.

Starscape Cleric

Offspring {2}{B} (You may pay an additional {2}{B} as you cast this spell. If you do, when this creature enters, create a 1/1 token copy of it.)
Flying
This creature can't block.
Whenever you gain life, each opponent loses 1 life.