Gravity Well

Whenever a creature with flying attacks, it loses flying until end of turn.

Arashi, the Sky Asunder

{X}{G}, {T}: Arashi, the Sky Asunder deals X damage to target creature with flying.
Channel — {X}{G}{G}, Discard Arashi: Arashi deals X damage to each creature with flying.

Archetype of Aggression

Creatures you control have trample.
Creatures your opponents control lose trample and can't have or gain trample.

Invert the Skies

Creatures your opponents control lose flying until end of turn if {G} was spent to cast this spell, and creatures you control gain flying until end of turn if {U} was spent to cast this spell. (Do both if {G}{U} was spent.)

Squall

Squall deals 2 damage to each creature with flying.

Sandwurm Convergence

Creatures with flying can't attack you or planeswalkers you control.
At the beginning of your end step, create a 5/5 green Wurm creature token.

Silklash Spider

Reach
{X}{G}{G}: Silklash Spider deals X damage to each creature with flying.

Bow of Nylea

Attacking creatures you control have deathtouch.
{1}{G}, {T}: Choose one —
• Put a +1/+1 counter on target creature.
• Bow of Nylea deals 2 damage to target creature with flying.
• You gain 3 life.
• Put up to four target cards from your graveyard on the bottom of your library in any order.

Archetype of Imagination

Creatures you control have flying.
Creatures your opponents control lose flying and can't have or gain flying.

Mystic Decree

All creatures lose flying and islandwalk.

Whiteout

All creatures lose flying until end of turn.
Sacrifice a snow land: Return Whiteout from your graveyard to your hand.

Hurricane

Hurricane deals X damage to each creature with flying and each player.

Gravity Sphere

Palazzo Archers

Reach
Whenever a creature with flying attacks you or a planeswalker you control, Palazzo Archers deals damage equal to its power to that creature.

Chaosphere

Creatures with flying can block only creatures with flying.
Creatures without flying have reach. (They can block creatures with flying.)

Windreader Sphinx

Flying
Whenever a creature with flying attacks, you may draw a card.

Archetype of Endurance

Creatures you control have hexproof.
Creatures your opponents control lose hexproof and can't have or gain hexproof.

Scourge of Kher Ridges

Flying
{1}{R}: Scourge of Kher Ridges deals 2 damage to each creature without flying.
{5}{R}: Scourge of Kher Ridges deals 6 damage to each other creature with flying.

Whiptongue Hydra

Reach
When Whiptongue Hydra enters, destroy all creatures with flying. Put a +1/+1 counter on Whiptongue Hydra for each creature destroyed this way.

Raking Canopy

Whenever a creature with flying attacks you, Raking Canopy deals 4 damage to it.

Riku of Two Reflections

Whenever you cast an instant or sorcery spell, you may pay {U}{R}. If you do, copy that spell. You may choose new targets for the copy.
Whenever another nontoken creature you control enters, you may pay {G}{U}. If you do, create a token that's a copy of that creature.