Have

Plains

Pontiff of Blight

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Other creatures you control have extort. (If a creature has multiple instances of extort, each triggers separately.)

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Don't Have

Shard of the Nightbringer

Flying
Drain Life — When Shard of the Nightbringer enters, if you cast it, target opponent loses half their life, rounded up. You gain life equal to the life lost this way.

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Dire Fleet Ravager

Menace, deathtouch
When Dire Fleet Ravager enters, each player loses a third of their life, rounded up.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Quietus Spike

Equipped creature has deathtouch.
Whenever equipped creature deals combat damage to a player, that player loses half their life, rounded up.
Equip {3}

Twilight Prophet

Flying
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your upkeep, if you have the city's blessing, reveal the top card of your library and put it into your hand. Each opponent loses X life and you gain X life, where X is that card's mana value.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Mortify

Terramorphic Expanse

{T}, Sacrifice Terramorphic Expanse: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Suture Priest

Whenever another creature you control enters, you may gain 1 life.
Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Test of Endurance

At the beginning of your upkeep, if you have 50 or more life, you win the game.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Merciless Eviction

Choose one —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all planeswalkers.

Mana Crypt

At the beginning of your upkeep, flip a coin. If you lose the flip, Mana Crypt deals 3 damage to you.
{T}: Add {C}{C}.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Evolving Wilds

{T}, Sacrifice Evolving Wilds: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Sol Ring

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

Farewell

Choose one or more —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all graveyards.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Soul's Attendant

Whenever another creature enters, you may gain 1 life.

Felidar Sovereign

Vigilance, lifelink
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Elas il-Kor, Sadistic Pilgrim

Deathtouch
Whenever another creature you control enters, you gain 1 life.
Whenever another creature you control dies, each opponent loses 1 life.

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature and you return up to one target creature card from your graveyard to your hand.

Forlorn Flats

Forlorn Flats enters tapped.
When Forlorn Flats enters, it deals 1 damage to target opponent.
{T}: Add {W} or {B}.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Soul Warden

Whenever another creature enters, you gain 1 life.

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Angelic Accord

At the beginning of each end step, if you gained 4 or more life this turn, create a 4/4 white Angel creature token with flying.

Marble Diamond

Marble Diamond enters tapped.
{T}: Add {W}.

Charcoal Diamond

Charcoal Diamond enters tapped.
{T}: Add {B}.

Court of Ambition

When Court of Ambition enters, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Ghostly Prison

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Damn

Destroy target creature. A creature destroyed this way can't be regenerated.
Overload {2}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Radiant Fountain

When Radiant Fountain enters, you gain 2 life.
{T}: Add {C}.

Darkstar Augur

Offspring {B} (You may pay an additional {B} as you cast this spell. If you do, when this creature enters, create a 1/1 token copy of it.)
Flying
At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Vona, Butcher of Magan

Vigilance, lifelink
{T}, Pay 7 life: Destroy target nonland permanent. Activate only during your turn.

Bloodthirsty Aerialist

Flying
Whenever you gain life, put a +1/+1 counter on Bloodthirsty Aerialist.

Pristine Talisman

Vraan, Executioner Thane

Whenever one or more other creatures you control die, each opponent loses 2 life and you gain 2 life. This ability triggers only once each turn.

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life.

Boon Reflection

If you would gain life, you gain twice that much life instead.

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Witch's Cottage

({T}: Add {B}.)
Witch's Cottage enters tapped unless you control three or more other Swamps.
When Witch's Cottage enters untapped, you may put target creature card from your graveyard on top of your library.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Scourge of the Skyclaves

Kicker {4}{B}
When you cast this spell, if it was kicked, each player loses half their life, rounded up.
Scourge of the Skyclaves's power and toughness are each equal to 20 minus the highest life total among players.

The Meathook Massacre

When The Meathook Massacre enters, each creature gets -X/-X until end of turn.
Whenever a creature you control dies, each opponent loses 1 life.
Whenever a creature an opponent controls dies, you gain 1 life.

Indulging Patrician

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your end step, if you gained 3 or more life this turn, each opponent loses 3 life.

Sorin Markov

+2: Sorin Markov deals 2 damage to any target and you gain 2 life.
−3: Target opponent's life total becomes 10.
−7: You control target player during that player's next turn.

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Charismatic Conqueror

Vigilance
Whenever an artifact or creature an opponent controls enters untapped, they may tap that permanent. If they don't, you create a 1/1 white Vampire creature token with lifelink.

Nykthos Paragon

Whenever you gain life, you may put that many +1/+1 counters on each creature you control. Do this only once each turn.

Murder

Swamp

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Jet Medallion

Black spells you cast cost {1} less to cast.

Rodolf Duskbringer

Flying, deathtouch, lifelink
Whenever you gain life, Rodolf Duskbringer gains indestructible until end of turn.
At the beginning of your end step, you may pay {1}{W/B}. When you do, return target creature card with mana value X or less from your graveyard to the battlefield, where X is the amount of life you gained this turn.

Falkenrath Noble

Flying
Whenever Falkenrath Noble or another creature dies, target player loses 1 life and you gain 1 life.