Curse of Fool's Wisdom

Enchant player
Whenever enchanted player draws a card, they lose 2 life and you gain 2 life.
Madness {3}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Unforgiving One

Menace (This creature can't be blocked except by two or more creatures.)
Whenever Unforgiving One attacks, return target creature card with mana value X or less from your graveyard to the battlefield, where X is the number of modified creatures you control. (Equipment, Auras you control, and counters are modifications.)

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Undead Butler

When Undead Butler enters, mill three cards. (Put the top three cards of your library into your graveyard.)
When Undead Butler dies, you may exile it. When you do, return target creature card from your graveyard to your hand.

Endless One

Endless One enters with X +1/+1 counters on it.

Vein Ripper

Flying
Ward—Sacrifice a creature.
Whenever a creature dies, target opponent loses 2 life and you gain 2 life.

Vampire's Bite

Kicker {2}{B} (You may pay an additional {2}{B} as you cast this spell.)
Target creature gets +3/+0 until end of turn. If this spell was kicked, that creature gains lifelink until end of turn. (Damage dealt by the creature also causes its controller to gain that much life.)

Cast Down

Profane Memento

Whenever a creature card is put into an opponent's graveyard from anywhere, you gain 1 life.

Gauntlet of Power

As Gauntlet of Power enters, choose a color.
Creatures of the chosen color get +1/+1.
Whenever a basic land is tapped for mana of the chosen color, its controller adds an additional one mana of that color.

Soul Transfer

Choose one. If you control an artifact and an enchantment as you cast this spell, you may choose both instead.
• Exile target creature or planeswalker.
• Return target creature or planeswalker card from your graveyard to your hand.

Blood Seeker

Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Infernal Darkness

Cumulative upkeep—Pay {B} and 1 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
If a land is tapped for mana, it produces {B} instead of any other type.

Rise of the Dark Realms

Put all creature cards from all graveyards onto the battlefield under your control.

Blood Tithe

Each opponent loses 3 life. You gain life equal to the life lost this way.

Malakir Cullblade

Whenever a creature an opponent controls dies, put a +1/+1 counter on Malakir Cullblade.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Doom Whisperer

Flying, trample
Pay 2 life: Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Blood Reckoning

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life.

Murder

Rancid Rats

Skulk (This creature can't be blocked by creatures with greater power.)
Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)

Liliana's Contract

When Liliana's Contract enters, you draw four cards and you lose 4 life.
At the beginning of your upkeep, if you control four or more Demons with different names, you win the game.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Colossus of Akros

Defender, indestructible
{10}: Monstrosity 10. (If this creature isn't monstrous, put ten +1/+1 counters on it and it becomes monstrous.)
As long as Colossus of Akros is monstrous, it has trample and can attack as though it didn't have defender.

Darksteel Plate

Indestructible
Equipped creature has indestructible.
Equip {2}

Blood Tribute

Kicker—Tap an untapped Vampire you control. (You may tap a Vampire you control in addition to any other costs as you cast this spell.)
Target opponent loses half their life, rounded up. If this spell was kicked, you gain life equal to the life lost this way.

Hissing Miasma

Whenever a creature attacks you, its controller loses 1 life.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Nightmare

Flying (This creature can't be blocked except by creatures with flying or reach.)
Nightmare's power and toughness are each equal to the number of Swamps you control.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Dictate of Erebos

Flash
Whenever a creature you control dies, each opponent sacrifices a creature of their choice.

Archon of Cruelty

Flying
Whenever Archon of Cruelty enters or attacks, target opponent sacrifices a creature or planeswalker of their choice, discards a card, and loses 3 life. You draw a card and gain 3 life.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Mire's Grasp

Enchant creature
Enchanted creature gets -3/-3.

Pact Weapon

As long as Pact Weapon is attached to a creature, you don't lose the game for having 0 or less life.
Whenever equipped creature attacks, draw a card and reveal it. The creature gets +X/+X until end of turn and you lose X life, where X is that card's mana value.
Equip—Discard a card.

Kaldra Compleat

Living weapon
Indestructible
Equipped creature gets +5/+5 and has first strike, trample, indestructible, haste, and "Whenever this creature deals combat damage to a creature, exile that creature."
Equip {7}

Lashwrithe

Living weapon (When this Equipment enters, create a 0/0 black Phyrexian Germ creature token, then attach this to it.)
Equipped creature gets +1/+1 for each Swamp you control.
Equip {B/P}{B/P} ({B/P} can be paid with either {B} or 2 life.)

Bloodvial Purveyor

Flying, trample
Whenever an opponent casts a spell, that player creates a Blood token. (It's an artifact with "{1}, {T}, Discard a card, Sacrifice this artifact: Draw a card.")
Whenever Bloodvial Purveyor attacks, it gets +1/+0 until end of turn for each Blood token defending player controls.

Vampire Nighthawk

Flying
Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Eldritch Pact

Target player draws X cards and loses X life, where X is the number of cards in their graveyard.

Virulent Plague

Swamp

Sadistic Sacrament

Kicker {7} (You may pay an additional {7} as you cast this spell.)
Search target player's library for up to three cards, exile them, then that player shuffles. If this spell was kicked, instead search that player's library for up to fifteen cards, exile them, then that player shuffles.

Mikaeus, the Unhallowed

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
Whenever a Human deals damage to you, destroy it.
Other non-Human creatures you control get +1/+1 and have undying. (When a creature with undying dies, if it had no +1/+1 counters on it, return it to the battlefield under its owner's control with a +1/+1 counter on it.)

Shadowborn Demon

Flying
When Shadowborn Demon enters, destroy target non-Demon creature.
At the beginning of your upkeep, if there are fewer than six creature cards in your graveyard, sacrifice a creature.

Black Dragon

Flying
Acid Breath — When Black Dragon enters, target creature an opponent controls gets -3/-3 until end of turn.

Sengir Vampire

Flying (This creature can't be blocked except by creatures with flying or reach.)
Whenever a creature dealt damage by Sengir Vampire this turn dies, put a +1/+1 counter on Sengir Vampire.

Kaya's Ghostform

Enchant creature or planeswalker you control
When enchanted permanent dies or is put into exile, return that card to the battlefield under your control.

Typhoid Rats

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)

Blood Curdle

Destroy target creature. Put a menace counter on a creature you control. (It can't be blocked except by two or more creatures.)

Archetype of Finality

Creatures you control have deathtouch.
Creatures your opponents control lose deathtouch and can't have or gain deathtouch.

Staff of the Death Magus

Whenever you cast a black spell or a Swamp you control enters, you gain 1 life.

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Torment of Scarabs

Enchant player
At the beginning of enchanted player's upkeep, that player loses 3 life unless they sacrifice a nonland permanent of their choice or discard a card.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Crowded Crypt

{T}: Add {B}.
Whenever a creature you control dies, put a corpse counter on Crowded Crypt.
{4}{B}{B}, {T}, Sacrifice Crowded Crypt: Create a 2/2 black Zombie creature token with decayed for each corpse counter on Crowded Crypt. (A creature with decayed can't block. When it attacks, sacrifice it at end of combat.)

Sheoldred, Whispering One

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.
At the beginning of each opponent's upkeep, that player sacrifices a creature of their choice.

Karumonix, the Rat King

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
Other Rats you control have toxic 1.
When Karumonix enters, look at the top five cards of your library. You may reveal any number of Rat cards from among them and put the revealed cards into your hand. Put the rest on the bottom of your library in a random order.

Demonlord of Ashmouth

Flying
When Demonlord of Ashmouth enters, exile it unless you sacrifice another creature.
Undying (When this creature dies, if it had no +1/+1 counters on it, return it to the battlefield under its owner's control with a +1/+1 counter on it.)

Bloodchief's Thirst

Kicker {2}{B} (You may pay an additional {2}{B} as you cast this spell.)
Destroy target creature or planeswalker with mana value 2 or less. If this spell was kicked, instead destroy target creature or planeswalker.

Baleful Beholder

When Baleful Beholder enters, choose one —
• Antimagic Cone — Each opponent sacrifices an enchantment of their choice.
• Fear Ray — Creatures you control gain menace until end of turn. (A creature with menace can't be blocked except by two or more creatures.)

World-Weary

Enchant creature
Enchanted creature gets -4/-4.
Basic landcycling {1}{B} ({1}{B}, Discard this card: Search your library for a basic land card, reveal it, put it into your hand, then shuffle.)

Finale of Eternity

Destroy up to three target creatures with toughness X or less. If X is 10 or more, return all creature cards from your graveyard to the battlefield.

Mogis's Favor

Enchant creature
Enchanted creature gets +2/-1.
Escape—{2}{B}, Exile two other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)