Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Have

Blood Seeker

Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Bastion of Remembrance

When Bastion of Remembrance enters, create a 1/1 white Human Soldier creature token.
Whenever a creature you control dies, each opponent loses 1 life and you gain 1 life.

Zo-Zu the Punisher

Whenever a land enters, Zo-Zu the Punisher deals 2 damage to that land's controller.

Swamp

Graven Cairns

{T}: Add {C}.
{B/R}, {T}: Add {B}{B}, {B}{R}, or {R}{R}.

Geier Reach Sanitarium

{T}: Add {C}.
{2}, {T}: Each player draws a card, then discards a card.

Nowhere to Run

Flash
When Nowhere to Run enters, target creature an opponent controls gets -3/-3 until end of turn.
Creatures your opponents control can be the targets of spells and abilities as though they didn't have hexproof. Ward abilities of those creatures don't trigger.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Sulfurous Springs

{T}: Add {C}.
{T}: Add {B} or {R}. Sulfurous Springs deals 1 damage to you.

Mayhem Devil

Whenever a player sacrifices a permanent, Mayhem Devil deals 1 damage to any target.

Vial Smasher the Fierce

Whenever you cast your first spell each turn, choose an opponent at random. Vial Smasher the Fierce deals damage equal to that spell's mana value to that player or a planeswalker that player controls.
Partner (You can have two commanders if both have partner.)

Sleeper's Guile

Enchant creature
Enchanted creature has fear. (It can't be blocked except by artifact creatures and/or black creatures.)
When Sleeper's Guile is put into a graveyard from the battlefield, return Sleeper's Guile to its owner's hand.

Mask of Griselbrand

Equipped creature has flying and lifelink.
Whenever equipped creature dies, you may pay X life, where X is its power. If you do, draw X cards.
Equip {3}

Spinerock Knoll

Hideaway 4 (When this land enters, look at the top four cards of your library, exile one face down, then put the rest on the bottom in a random order.)
Spinerock Knoll enters tapped.
{T}: Add {R}.
{R}, {T}: You may play the exiled card without paying its mana cost if an opponent was dealt 7 or more damage this turn.

Ash Barrens

{T}: Add {C}.
Basic landcycling {1} ({1}, Discard this card: Search your library for a basic land card, reveal it, put it into your hand, then shuffle.)

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Blood Pact

Target player draws two cards and loses 2 life.

Tyrite Sanctum

{T}: Add {C}.
{2}, {T}: Target legendary creature becomes a God in addition to its other types. Put a +1/+1 counter on it.
{4}, {T}, Sacrifice Tyrite Sanctum: Put an indestructible counter on target God.

Nightshade Harvester

Whenever a land an opponent controls enters, that player loses 1 life. Put a +1/+1 counter on Nightshade Harvester.

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Canyon Slough

({T}: Add {B} or {R}.)
Canyon Slough enters tapped.
Cycling {2} ({2}, Discard this card: Draw a card.)

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Ring of Valkas

Equipped creature has haste. (It can attack and {T} no matter when it came under your control.)
At the beginning of your upkeep, put a +1/+1 counter on equipped creature if it's red.
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Smoldering Marsh

({T}: Add {B} or {R}.)
Smoldering Marsh enters tapped unless you control two or more basic lands.

Kederekt Parasite

Whenever an opponent draws a card, if you control a red permanent, you may have Kederekt Parasite deal 1 damage to that player.

Terramorphic Expanse

{T}, Sacrifice Terramorphic Expanse: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Sol Ring

Massacre Girl

Menace
When Massacre Girl enters, each other creature gets -1/-1 until end of turn. Whenever a creature dies this turn, each creature other than Massacre Girl gets -1/-1 until end of turn.

Theater of Horrors

At the beginning of your upkeep, exile the top card of your library.
During your turn, if an opponent lost life this turn, you may play lands and cast spells from among cards exiled with Theater of Horrors.
{3}{R}: Theater of Horrors deals 1 damage to target opponent or planeswalker.

Rakdos, Lord of Riots

You can't cast this spell unless an opponent lost life this turn.
Flying, trample
Creature spells you cast cost {1} less to cast for each 1 life your opponents have lost this turn.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Kardur, Doomscourge

When Kardur, Doomscourge enters, until your next turn, creatures your opponents control attack each combat if able and attack a player other than you if able.
Whenever an attacking creature dies, each opponent loses 1 life and you gain 1 life.

Decree of Pain

Destroy all creatures. They can't be regenerated. Draw a card for each creature destroyed this way.
Cycling {3}{B}{B} ({3}{B}{B}, Discard this card: Draw a card.)
When you cycle Decree of Pain, all creatures get -2/-2 until end of turn.

Combustible Gearhulk

First strike
When Combustible Gearhulk enters, target opponent may have you draw three cards. If the player doesn't, you mill three cards, then Combustible Gearhulk deals damage to that player equal to the total mana value of those cards.

Rakdos Charm

Choose one —
• Exile target player's graveyard.
• Destroy target artifact.
• Each creature deals 1 damage to its controller.

Damnation

Destroy all creatures. They can't be regenerated.

Aphotic Wisps

Target creature becomes black and gains fear until end of turn. (It can't be blocked except by artifact creatures and/or black creatures.)
Draw a card.

Spiteful Visions

At the beginning of each player's draw step, that player draws an additional card.
Whenever a player draws a card, Spiteful Visions deals 1 damage to that player.

Ankh of Mishra

Whenever a land enters, Ankh of Mishra deals 2 damage to that land's controller.

Infernal Grasp

Destroy target creature. You lose 2 life.

Cemetery Gatekeeper

First strike
When Cemetery Gatekeeper enters, exile a card from a graveyard.
Whenever a player plays a land or casts a spell, if it shares a card type with the exiled card, Cemetery Gatekeeper deals 2 damage to that player.

Syr Konrad, the Grim

Whenever another creature dies, or a creature card is put into a graveyard from anywhere other than the battlefield, or a creature card leaves your graveyard, Syr Konrad, the Grim deals 1 damage to each opponent.
{1}{B}: Each player mills a card. (They each put the top card of their library into their graveyard.)

Disrupt Decorum

Goad all creatures you don't control. (Until your next turn, those creatures attack each combat if able and attack a player other than you if able.)

Tainted Peak

{T}: Add {C}.
{T}: Add {B} or {R}. Activate only if you control a Swamp.

Morbid Opportunist

Whenever one or more other creatures die, draw a card. This ability triggers only once each turn.

Light Up the Stage

Spectacle {R} (You may cast this spell for its spectacle cost rather than its mana cost if an opponent lost life this turn.)
Exile the top two cards of your library. Until the end of your next turn, you may play those cards.

Solemn Simulacrum

When Solemn Simulacrum enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When Solemn Simulacrum dies, you may draw a card.

Pyrohemia

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pyrohemia.
{R}: Pyrohemia deals 1 damage to each creature and each player.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Braids, Arisen Nightmare

At the beginning of your end step, you may sacrifice an artifact, creature, enchantment, land, or planeswalker. If you do, each opponent may sacrifice a permanent that shares a card type with it. For each opponent who doesn't, that player loses 2 life and you draw a card.

Talisman of Indulgence

{T}: Add {C}.
{T}: Add {B} or {R}. Talisman of Indulgence deals 1 damage to you.

Enchanter's Bane

At the beginning of your end step, target enchantment deals damage equal to its mana value to its controller unless that player sacrifices it.

Ring of Xathrid

{2}: Regenerate equipped creature. (The next time that creature would be destroyed this turn, it isn't. Instead tap it, remove all damage from it, and remove it from combat.)
At the beginning of your upkeep, put a +1/+1 counter on equipped creature if it's black.
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Bloodfell Caves

Bloodfell Caves enters tapped.
When Bloodfell Caves enters, you gain 1 life.
{T}: Add {B} or {R}.

Demonic Counsel

Search your library for a Demon card, reveal it, put it into your hand, then shuffle.
Delirium — If there are four or more card types among cards in your graveyard, instead search your library for any card, put it into your hand, then shuffle.

Sanguine Morass

Sanguine Morass enters tapped.
{T}: Add {B} or {R}.

Bloodsoaked Insight

This spell costs {1} less to cast for each 1 life your opponents have lost this turn.
Target opponent exiles the top three cards of their library. Until the end of your next turn, you may play those cards. If you cast a spell this way, mana of any type can be spent to cast it.

Bloodsoaked Insight // Sanguine Morass

Witch's Clinic

{T}: Add {C}.
{2}, {T}: Target commander gains lifelink until end of turn.

Ashenmoor Liege

Other black creatures you control get +1/+1.
Other red creatures you control get +1/+1.
Whenever Ashenmoor Liege becomes the target of a spell or ability an opponent controls, that player loses 4 life.

Falkenrath Noble

Flying
Whenever Falkenrath Noble or another creature dies, target player loses 1 life and you gain 1 life.

Dark Ritual

Valgavoth's Lair

Hexproof
Valgavoth's Lair enters tapped. As it enters, choose a color.
{T}: Add one mana of the chosen color.

Sign in Blood

Oblivion's Hunger

Target creature you control gains indestructible until end of turn. Draw a card if that creature has a +1/+1 counter on it. (Damage and effects that say "destroy" don't destroy the creature.)

Auntie Blyte, Bad Influence

Flying
Whenever a source you control deals damage to you, put that many +1/+1 counters on Auntie Blyte, Bad Influence.
{1}{R}, {T}, Remove X +1/+1 counters from Auntie Blyte: It deals X damage to any target.

Shadowblood Ridge

Drannith Ruins

{T}: Add {C}.
{2}, {T}: Put two +1/+1 counters on target non-Human creature that entered this turn.

Neheb, the Eternal

Afflict 3 (Whenever this creature becomes blocked, defending player loses 3 life.)
At the beginning of your second main phase, add {R} for each 1 life your opponents have lost this turn.

Geothermal Bog

({T}: Add {B} or {R}.)
Geothermal Bog enters tapped.

Exotic Orchard

Sulfuric Vortex

At the beginning of each player's upkeep, Sulfuric Vortex deals 2 damage to that player.
If a player would gain life, that player gains no life instead.

Roiling Vortex

At the beginning of each player's upkeep, Roiling Vortex deals 1 damage to them.
Whenever a player casts a spell, if no mana was spent to cast that spell, Roiling Vortex deals 5 damage to that player.
{R}: Your opponents can't gain life this turn.

Foreboding Ruins

As Foreboding Ruins enters, you may reveal a Swamp or Mountain card from your hand. If you don't, Foreboding Ruins enters tapped.
{T}: Add {B} or {R}.

Shivan Gorge

{T}: Add {C}.
{2}{R}, {T}: Shivan Gorge deals 1 damage to each opponent.

Mogis, God of Slaughter

Indestructible
As long as your devotion to black and red is less than seven, Mogis isn't a creature.
At the beginning of each opponent's upkeep, Mogis deals 2 damage to that player unless they sacrifice a creature.

Temple of Malice

Temple of Malice enters tapped.
When Temple of Malice enters, scry 1.
{T}: Add {B} or {R}.

Gift of Doom

Enchant creature
Enchanted creature has deathtouch and indestructible.
Morph—Sacrifice another creature. (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)
As Gift of Doom is turned face up, you may attach it to a creature.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Dragonskull Summit

Dragonskull Summit enters tapped unless you control a Swamp or a Mountain.
{T}: Add {B} or {R}.

Deflecting Swat

If you control a commander, you may cast this spell without paying its mana cost.
You may choose new targets for target spell or ability.

Leechridden Swamp

({T}: Add {B}.)
Leechridden Swamp enters tapped.
{B}, {T}: Each opponent loses 1 life. Activate only if you control two or more black permanents.

Rampaging Ferocidon

Menace
Players can't gain life.
Whenever another creature enters, Rampaging Ferocidon deals 1 damage to that creature's controller.

Court of Ambition

When Court of Ambition enters, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Evolving Wilds

{T}, Sacrifice Evolving Wilds: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Blackcleave Cliffs

Blackcleave Cliffs enters tapped unless you control two or fewer other lands.
{T}: Add {B} or {R}.

Kaervek the Merciless

Whenever an opponent casts a spell, Kaervek the Merciless deals damage equal to that spell's mana value to any target.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Pestilence

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pestilence.
{B}: Pestilence deals 1 damage to each creature and each player.

Gix's Command

Choose two —
• Put two +1/+1 counters on up to one creature. It gains lifelink until end of turn.
• Destroy each creature with power 2 or less.
• Return up to two creature cards from your graveyard to your hand.
• Each opponent sacrifices a creature with the highest power among creatures they control.

Fear of Burning Alive

When Fear of Burning Alive enters, it deals 4 damage to each opponent.
Delirium — Whenever a source you control deals noncombat damage to an opponent, if there are four or more card types among cards in your graveyard, Fear of Burning Alive deals that amount of damage to target creature that player controls.

Unexpected Fangs

Put a +1/+1 counter and a lifelink counter on target creature.

Tectonic Giant

Whenever Tectonic Giant attacks or becomes the target of a spell an opponent controls, choose one —
• Tectonic Giant deals 3 damage to each opponent.
• Exile the top two cards of your library. Choose one of them. Until the end of your next turn, you may play that card.

Lightning Bolt

Lightning Bolt deals 3 damage to any target.

Havoc Festival

Players can't gain life.
At the beginning of each player's upkeep, that player loses half their life, rounded up.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Grab the Prize

As an additional cost to cast this spell, discard a card.
Draw two cards. If the discarded card wasn't a land card, Grab the Prize deals 2 damage to each opponent.

Rain of Gore

If a spell or ability would cause its controller to gain life, that player loses that much life instead.

Valgavoth, Harrower of Souls

Flying
Ward—Pay 2 life.
Whenever an opponent loses life for the first time during each of their turns, put a +1/+1 counter on Valgavoth, Harrower of Souls and draw a card.

Solphim, Mayhem Dominus

If a source you control would deal noncombat damage to an opponent or a permanent an opponent controls, it deals double that damage to that player or permanent instead.
{1}{R/P}{R/P}, Discard two cards: Put an indestructible counter on Solphim, Mayhem Dominus. ({R/P} can be paid with either {R} or 2 life.)

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Stormfist Crusader

Menace
At the beginning of your upkeep, each player draws a card and loses 1 life.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.