Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Tinybones, Trinket Thief

At the beginning of each end step, if an opponent discarded a card this turn, you draw a card and you lose 1 life.
{4}{B}{B}: Each opponent with no cards in hand loses 10 life.

Necrogen Mists

At the beginning of each player's upkeep, that player discards a card.

Geth's Grimoire

Whenever an opponent discards a card, you may draw a card.

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Vedalken Orrery

You may cast spells as though they had flash.

Bottomless Pit

At the beginning of each player's upkeep, that player discards a card at random.

Cunning Lethemancer

At the beginning of your upkeep, each player discards a card.

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.