Trailblazer

Target creature can't be blocked this turn.

Sewers of Estark

Choose target creature. If it's attacking, it can't be blocked this turn. If it's blocking, prevent all combat damage that would be dealt this combat by it and each creature it's blocking.

Heroic Intervention

Permanents you control gain hexproof and indestructible until end of turn.

Key to the City

{T}, Discard a card: Up to one target creature can't be blocked this turn.
Whenever this artifact becomes untapped, you may pay {2}. If you do, draw a card.

Whispersilk Cloak

Equipped creature can't be blocked and has shroud. (It can't be the target of spells or abilities.)
Equip {2}

Vraska the Unseen

+1: Until your next turn, whenever a creature deals combat damage to Vraska, destroy that creature.
−3: Destroy target nonland permanent.
−7: Create three 1/1 black Assassin creature tokens with "Whenever this token deals combat damage to a player, that player loses the game."

Tawnos's Wand

{2}, {T}: Target creature with power 2 or less can't be blocked this turn.

Bellowing Tanglewurm

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
Other green creatures you control have intimidate.

Glaring Spotlight

Creatures your opponents control with hexproof can be the targets of spells and abilities you control as though they didn't have hexproof.
{3}, Sacrifice this artifact: Creatures you control gain hexproof until end of turn and can't be blocked this turn.

Rogue's Passage

{T}: Add {C}.
{4}, {T}: Target creature can't be blocked this turn.

Manifold Key

{1}, {T}: Untap another target artifact.
{3}, {T}: Target creature can't be blocked this turn.