Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, Serra Ascendant gets +5/+5 and has flying.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Ad Nauseam

Reveal the top card of your library and put that card into your hand. You lose life equal to its mana value. You may repeat this process any number of times.

Griffin Aerie

At the beginning of your end step, if you gained 3 or more life this turn, create a 2/2 white Griffin creature token with flying.

Nashi, Moon Sage's Scion

Ninjutsu {3}{B} ({3}{B}, Return an unblocked attacker you control to hand: Put this card onto the battlefield from your hand tapped and attacking.)
Whenever Nashi, Moon Sage's Scion deals combat damage to a player, exile the top card of each player's library. Until end of turn, you may play one of those cards. If you cast a spell this way, pay life equal to its mana value rather than paying its mana cost.

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Shadowgrange Archfiend

When Shadowgrange Archfiend enters, each opponent sacrifices a creature with the greatest power among creatures they control. You gain life equal to the greatest power among creatures sacrificed this way.
Madness—{2}{B}, Pay 8 life. (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Vona, Butcher of Magan

Vigilance, lifelink
{T}, Pay 7 life: Destroy target nonland permanent. Activate only during your turn.

Luminous Broodmoth

Flying
Whenever a creature you control without flying dies, return it to the battlefield under its owner's control with a flying counter on it.

Bloodthirsty Aerialist

Flying
Whenever you gain life, put a +1/+1 counter on Bloodthirsty Aerialist.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Guardian of Faith

Flash
Vigilance
When Guardian of Faith enters, any number of other target creatures you control phase out. (Treat them and anything attached to them as though they don't exist until their controller's next turn.)

Deadly Rollick

If you control a commander, you may cast this spell without paying its mana cost.
Exile target creature.

Thalia, Heretic Cathar

First strike
Creatures and nonbasic lands your opponents control enter tapped.

Radiant Fountain

When Radiant Fountain enters, you gain 2 life.
{T}: Add {C}.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Idyllic Tutor

Search your library for an enchantment card, reveal it, put it into your hand, then shuffle.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Commissar Severina Raine

Leading from the Front — Whenever Commissar Severina Raine attacks, each opponent loses X life, where X is the number of other attacking creatures.
Summary Execution — {2}, Sacrifice another creature: You gain 2 life and draw a card.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent or discards a card.

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature and you return up to one target creature card from your graveyard to your hand.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Righteous Valkyrie

Flying
Whenever another Angel or Cleric you control enters, you gain life equal to that creature's toughness.
As long as you have at least 7 life more than your starting life total, creatures you control get +2/+2.

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.

Callous Bloodmage

When Callous Bloodmage enters, choose one —
• Create a 1/1 black and green Pest creature token with "When this creature dies, you gain 1 life."
• You draw a card and you lose 1 life.
• Exile target player's graveyard.

Dire Tactics

Exile target creature. If you don't control a Human, you lose life equal to that creature's toughness.

Blood Tribute

Kicker—Tap an untapped Vampire you control. (You may tap a Vampire you control in addition to any other costs as you cast this spell.)
Target opponent loses half their life, rounded up. If this spell was kicked, you gain life equal to the life lost this way.

Command Tower

Heliod's Intervention

Choose one —
• Destroy X target artifacts and/or enchantments.
• Target player gains twice X life.

Indulging Patrician

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your end step, if you gained 3 or more life this turn, each opponent loses 3 life.

Elas il-Kor, Sadistic Pilgrim

Deathtouch
Whenever another creature you control enters, you gain 1 life.
Whenever another creature you control dies, each opponent loses 1 life.

Twinblade Paladin

Whenever you gain life, put a +1/+1 counter on Twinblade Paladin.
As long as you have 25 or more life, Twinblade Paladin has double strike. (It deals both first-strike and regular combat damage.)

Heliod, Sun-Crowned

Indestructible
As long as your devotion to white is less than five, Heliod isn't a creature.
Whenever you gain life, put a +1/+1 counter on target creature or enchantment you control.
{1}{W}: Another target creature gains lifelink until end of turn.

Seasoned Cathar

Ambitious Farmhand

When Ambitious Farmhand enters, you may search your library for a basic Plains card, reveal it, put it into your hand, then shuffle.
Coven — {1}{W}{W}: Transform Ambitious Farmhand. Activate only if you control three or more creatures with different powers.

Ambitious Farmhand // Seasoned Cathar

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Grimclimb Pathway

Brightclimb Pathway

Brightclimb Pathway // Grimclimb Pathway

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Ajani's Pridemate

Whenever you gain life, put a +1/+1 counter on Ajani's Pridemate.

Massacre Wurm

When Massacre Wurm enters, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Selfless Spirit

Flying
Sacrifice Selfless Spirit: Creatures you control gain indestructible until end of turn.

Blot Out the Sky

Create X tapped 2/1 white and black Inkling creature tokens with flying. If X is 6 or more, destroy all noncreature, nonland permanents.

Imp's Mischief

Change the target of target spell with a single target. You lose life equal to that spell's mana value.

Swamp

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Prismatic Lens

{T}: Add {C}.
{1}, {T}: Add one mana of any color.

Angel of the Ruins

Flying
When Angel of the Ruins enters, exile up to two target artifacts and/or enchantments.
Plainscycling {2} ({2}, Discard this card: Search your library for a Plains card, reveal it, put it into your hand, then shuffle.)

Elesh Norn, Grand Cenobite

Vigilance
Other creatures you control get +2/+2.
Creatures your opponents control get -2/-2.

Felidar Sovereign

Vigilance, lifelink
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Test of Endurance

At the beginning of your upkeep, if you have 50 or more life, you win the game.

Celestine, the Living Saint

Flying, lifelink
Healing Tears — At the beginning of your end step, return target creature card with mana value X or less from your graveyard to the battlefield, where X is the amount of life you gained this turn.

Dawn of Hope

Whenever you gain life, you may pay {2}. If you do, draw a card.
{3}{W}: Create a 1/1 white Soldier creature token with lifelink.

Cleric Class

(Gain the next level as a sorcery to add its ability.)
If you would gain life, you gain that much life plus 1 instead.
{3}{W}: Level 2
Whenever you gain life, put a +1/+1 counter on target creature you control.
{4}{W}: Level 3
When this Class becomes level 3, return target creature card from your graveyard to the battlefield. You gain life equal to that creature's toughness.

Exquisite Archangel

Flying
If you would lose the game, instead exile Exquisite Archangel and your life total becomes equal to your starting life total.

Plains

Vona's Hunger

Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
Each opponent sacrifices a creature. If you have the city's blessing, instead each opponent sacrifices half the creatures they control, rounded up.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Daxos, Blessed by the Sun

Daxos's toughness is equal to your devotion to white. (Each {W} in the mana costs of permanents you control counts toward your devotion to white.)
Whenever another creature you control enters or dies, you gain 1 life.

Sol Ring

Storm Herd

Create X 1/1 white Pegasus creature tokens with flying, where X is your life total.

Sister Hospitaller

Medicus Ministorum — When Sister Hospitaller enters, return target creature card from your graveyard to the battlefield. You gain life equal to its mana value.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Crypt Incursion

Exile all creature cards from target player's graveyard. You gain 3 life for each card exiled this way.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Speaker of the Heavens

Vigilance, lifelink
{T}: Create a 4/4 white Angel creature token with flying. Activate only if you have at least 7 life more than your starting life total and only as a sorcery.